Answered Question about protein consumption and muscle synthesis?

[Cheeky Monkey]

I understand that muscle protein synthesis will start in the presence of protein. But does the speed of synthesis get affected by the presence of fat and carbohydrates along with the protein? For example, would I elicit a better protein synthesis environment if I consume just a protein isolate shake vs a blend of protein, carbs, and fat?

Thanks.

 

[ValiantThor08]

I understand that muscle protein synthesis will start in the presence of protein. But does the speed of synthesis get affected by the presence of fat and carbohydrates along with the protein? For example, would I elicit a better protein synthesis environment if I consume just a protein isolate shake vs a blend of protein, carbs, and fat?

Thanks.

No, the addition of other macronutrients will not negatively impair protein synthesis. Some carbs with protein would be beneficial for protein synthesis. You do have to make sure you consume a complete protein source, and at a high enough amount to trigger mTOR and protein synthesis. About 3g of leucine being present. Why I always get at least 50g of protein per meal.

 

[Resolve10]

No it shouldn’t effect it should be fine either way.

Carbohydrate coingestion delays dietary protein digestion and absorption but does not modulate postprandial muscle protein accretion - PubMed

Carbohydrate coingestion with protein delays dietary protein digestion and absorption but does not modulate postprandial muscle protein accretion in healthy young or older men.

www.ncbi.nlm.nih.gov

 

[Cheeky Monkey]

No, the addition of other macronutrients will not negatively impair protein synthesis. Some carbs with protein would be beneficial for protein synthesis. You do have to make sure you consume a complete protein source, and at a high enough amount to trigger mTOR and protein synthesis. About 3g of leucine being present. Why I always get at least 50g of protein per meal.

Thanks for the reply. So does that mean I can just consume at least 3g of leucine per meal to keep protein synthesis signal on? I'm asking in reference to cutting where I can reduce overall calories but supplement with a heavy dose of leucine to still keep protein synthesis up and running.

 

[ValiantThor08]

Thanks for the reply. So does that mean I can just consume at least 3g of leucine per meal to keep protein synthesis signal on? I'm asking in reference to cutting where I can reduce overall calories but supplement with a heavy dose of leucine to still keep protein synthesis up and running.

I saw this leucine seminar where the phd was claiming about 1.5 to 2 hours after your meal, take 3g of leucine, alone, or with 20g high glycemic carb (some table sugar), to maintain protein synthesis longer.

 

[ValiantThor08]

 

[ValiantThor08]

The seminar is split up into multiple videos, so start there, use that as a reference to find the other ones.

 

[The Solution]

I saw this leucine seminar where the phd was claiming about 1.5 to 2 hours after your meal, take 3g of leucine, alone, or with 20g high glycemic carb (some table sugar), to maintain protein synthesis longer.

Optimal Protein Intake And Meal Frequency To Support Maximal Protein Synthesis and Muscle Mass

Optimal Protein Intake And Meal Frequency To Support Maximal Protein Synthesis and Muscle Mass - Download as a PDF or view online for free

www.slideshare.net

Excel PT PPT- Endurance and Strength Nutrition

Excel PT PPT- Endurance and Strength Nutrition - Download as a PDF or view online for free

www.slideshare.net

Protein Requirements: Amount, Timing, and Type

It's all in the detail. Evan Shy shares breaks down everything you want to know about your protein intake for anabolism.

www.biolayne.com

 

[Cheeky Monkey]

Thanks guys for the resources. I'll check them out.