So I've been dealing with puffy nipples(gyno) since I was a teen. They used to be so bad that they would get real dry and itchy. Luckily that has not happened in about 10 years. The odd thing is, within the past 5 years my nipples will sometimes get smaller, but always go back to being puffy and no it does not have to be cold for them to get smaller, it's just random. I am overweight and I've mentioned that in another post, but as I've stated my nipples have always been puffy. Just when I was leaner let's say 20% BF, it wasn't as bad. If I had to guy my BF now, I'd say it's anywhere from 30-35%. So in short, I'm looking for something to get rid of this issue. I just bought vitamin b6 as P5P and I've taken 100mg today and it helped for a few hours then stopped. I can't really find a concussive answer on how high I can does P5P without it being toxic. Also, I'm on Wellbutrin, so I don't know if that would mess with the P5P. Thanks in advanced for any advice.