hey, more good info there.......still at my age, i shouldnt tax the kidneys at all for that matter....the organs dont regenerate like liver or outhers, and the issue is mentioned on many sites selling it but dont elaborate on the risk.....ill keep looking online....the outher issue of reducing joint pain seems real for me also, and relatively quick, as stated by outhers....i must find the web sites that can explain the biological effects, good & bad.....