ATRIPLEX dimorphostegia
is a plant native to areas of Northern Africa, Xinjiang and western Pakistan.
This plant is chock full of interesting compounds including several Phytoecdysteroids and several known and prospective anabolic actives. This is likely the most interesing new anabolic plant Ive seen in decades. The issue is that many of the actives have really low oral bioavailability but topically they really shine.
A recent study compared a specific extract of this plant to Testosterone and Dianabol with interesting results.
In this study the Atriplex extract was referred to as "TEAD"
Weight gain and muscle mass.
Testosterone and Dianabol both increased the rate of muscle growth by 80%
20-HE by 76% and
TEAD by 112%!
(This shows that TEAD had a 32% Greater increase in the rate of muscle growth than both test and Dianabol.)
View attachment 245891
Muscle Mass Percentage
The muscle mass percentage was calculated using the mean mass of the muscle bundle of both right and left hindlimbs against the mean final body weight of rats in each group at the end of the study . The group receiving TEAD showed the highest percentage among all groups, two-fold compared to the negative control.
(This meaning TEAD was even better than dianabol or testosterone for muscle mass gain.)
View attachment 245892
Conclusions
The Atriplex dimorphostegia extract proved anabolic potency. This was represented by the increase in net muscle mass of gastrocnemius and soleus muscle, as well as an increase in the cross-sectional area of muscle fibers. Moreover, both 20-HE and TEAD exhibited a low androgenic effect on sex organs without increasing the weights of prostate and seminal vesicles of rats after administration for ten consecutive days. These findings indicate that A. dimorphostegia is a promising candidate for use as an anabolic agent.
The study showed that Atriplex (TEAD) was safe and showed no toxicity. They ran molecular modeling tests and confirmes that 20HE (20 hydroxyecdysterone) binds to the estrogen and not the androgen receptor. So the anabolic effects of 20HE at least are not related to androgen receptor binding.
20-HE has really low oral bioavailability but topically its amazing. We utilized the same method used to extract atractylodes for Exotherm to extract this for Formeron.
Without disclosing methods we are pulling all of the active compounds from the dry material and holding them in solution. This allows for a not only the 20HE and other phytoecdysteroids but MANY other compounds- Some of these include=
REF: SOURCE-
https://www.mdpi.com/2223-7747/12/1/206
Caffeoyl hexose-deoxyhexoside
Chlorogenic acid derivative
Isoorientin
Apigenin dihexoside
Liquiritin Ferulic acid
Kaempferol deoxyhexoside
Dihydroxy benzoic acid Caffeic acid
Caffeoyl hexose-deoxyhexoside isomer
Quercetin pentosyl hexoside
Rosmarinic acid hexoside
Retusin methyl ether
Tetrahydroxyflavan
Kaempferol
Isorhamnetin
Myricetin
Quercetin
Dihydroxybenzoyl hexose
Coumaroyl hydroxy-palmitic acid
Quercetin-galloyl-pentoside
Coumaroyl-hexose
Kaempferol–dideoxyhexoside
(Kaempferitrin)
Dicaffeoyl-spermidine
Syringetin
rutinoside
Acetylated kaempferol deoxyhexosyl hexoside
Kaempferol deoxyhexosyl hexoside
Isorhamnetin hexoside
Quercetin deoxyhexoside
Apigenin-C-hexoside
Daucosterol
(Sitogluside)
Isorhamnetin deoxhexosyl hexoside
Kaempferol glucuronide
Sinapic acid hexoside
Tamerexetin deoxyhexosyl hexoside
Apigenin-C-hexoside
Caffeoyl-coumaroyl spermidine
β-Sitosterol
Caffeoyl pinoresinol
Tetrahydroxyflavan
Portulasoid
butoxyseptanoside Isorhamnetin
Myricetin
Tetrahydroxyflavan
Ursolic acid
β/α-amyrin
20-hydroxyecdysone
Lupeol
Stigmasterol
Oleonolic acid
Septanoecdysone