Disruption of male sex hormones with regard to pesticides: pathophysiological and regulatory aspects.
Straube E, Straube W, Kruger E, Bradatsch M, Jacob-Meisel M, Rose HJ.
Institute of Occupational Medicine, University of Greifswald, Germany.
[email protected]
Several pesticides used as herbicides, insecticides and fungicides are known to be endocrine disrupting chemicals (EDCs). In three pair-matched studies we found changes in sex hormone concentrations and T-lymphocytes in relation to acute and chronic pesticide exposure.
After acute exposure, 1 day later the concentrations of testosterone and especially estradiol decreased. T4- and T8-lymphocytes slightly increased. Effects of chronic occupational pesticide exposure were expressed by a higher level of testosterone and a larger ratio of T4-/T8-lymphocytes in comparison to control persons. Concentrations of LH in exposed men were higher after exposure than before. We assume an inhibition of the aromatase system by testosterone metabolites. The studies show two effects with regard to the duration of exposure: a hormonal and immune suppression after acute exposure and an activation of both systems following chronic exposure.
That is just the abstract. If you work with pesticides im sure you inhale minute amounts of it. Think of it as anti-gonadatopin releasing hormone. not the best for test levels to say the least.
some men do not grow a significant amount of chest or facial hair, that is pretty much genetic. Some people get their 5 o clock shade 4 hours after they shave, some take 2 days...
i am not an endocrinologist by any means, you need to go to one and be diagnosed with secondary or primary hypogonadism. we can help you from there
