IronBusta
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29, M - athlete ~20 years, generally good health, 8-10%BF... Prior to TRT symptoms mainly were stagnant recovery, depression, and anxiety.
After about 2-3 years of attempting to bring my test levels back to norm with no success - (SERMS, herbs, diet, fats/cholesterol, stress reduction, cold showers, sex, you name it)... my highest lab came in about 380 TT, 5 FT, 17 E2 . After 2 years of testing low and feeling like **** I made the decision to jump on the bandwagon. Multiple labs and temporary SERM responses indicated secondary hypogonadism, as my LH/FSH was consistently on the low end ~1 without any outside help.
Anyways, skipping forward - I have connected with a doc and compounding pharmacy that has prescribed me the Cyp/HCG/Arimidex. Lab results below were @ 25mg Cyp EOD, 100iu HCG ED, and .25mg Arimidex EOD. I got labs primarily because I felt I tanked E2 - joints hurt, mood took a nose dive... seems that was the case. So in terms of AI, I'm planning on moving the Arimidex to E3-4D gauging libido/joints as indicator of dosing frequency.
My question to you guys are the other flags noted below in bold (BUN, Creatinine, A/G ratio, and Hemocrit... as well as Cortisol/DHEA)
Can low estrogen cause a significant enough state of dehydration to contribute to the BUN/Creatinine/A/G/Hemocrit? I realize hemocrit levels are going to rise some on injectable, as I'm headed to give blood this week. But I was really hoping I could avoid this - now I'm considering bringing Cyp down to 20mg EOD, or even 10mg ED SC along with HCG. Also, pre-treatment Hemocrit levels stayed between 46-48. Any thoughts?
In terms of the Cortisol/DHEA - This was an AM - fasted bloodwork, so cortisol is not too much of a concern - as I realize it fluctuates and multiple testing should be considered. The DHEA however, seems on the low end from what I've been learning. I've also read some studies mentioning DHEA may lower cortisol levels over a period of time. I was thinking about starting low (say 15mg 2xday), and then gauging how I feel. Any one care to share their experiences with DHEA?
Everything else seems to look pretty good for initial lab results, correct me if you think otherwise. Any input would be greatly appreciated. Thanks
BUN 25 High mg/dL 6-20 BN
Creatinine, Serum 1.35 High mg/dL 0.76-1.27 BN
Albumin, Serum 4.6 g/dL 3.5-5.5 BN
Globulin, Total 1.7 g/dL 1.5-4.5 BN
A/G Ratio 2.7 High 1.1-2.5 BN
Cholesterol, Total 128 mg/dL 100-199 BN
Triglycerides 55 mg/dL 0-149 BN
HDL Cholesterol 47 mg/dL >39 BN
VLDL Cholesterol Cal 11 mg/dL 5-40 BN
LDL Cholesterol Calc 70 mg/dL 0-99 BN
T. Chol/HDL Ratio 2.7 ratio units 0.0-5.0 BN
WBC 6.8 x10E3/uL 3.4-10.8 BN
RBC 5.41 x10E6/uL 4.14-5.80 BN
Hemoglobin 17.2 g/dL 12.6-17.7 BN
Hematocrit 50.1 % 37.5-51.0 BN
Testosterone, Serum 1110 ng/dL 348-1197 BN
Free Testosterone(Direct) 44.0 High pg/mL 9.3-26.5 BN
Pregnenolone, MS 139 ng/dL ES
Dihydrotestosterone 77 ng/dL ES
T4,Free(Direct) 1.22 ng/dL 0.82-1.77 BN
DHEA-Sulfate 151.3 ug/dL 138.5-475.2 BN
Cortisol 20.6 High ug/dL 2.3-19.4 BN
TSH 1.530 uIU/mL 0.450-4.500 BN
Estradiol 13.3 pg/mL 7.6-42.6 BN
Prostate Specific Ag, Serum 0.6 ng/mL 0.0-4.0 BN
Triiodothyronine,Free,Serum 2.8 pg/mL 2.0-4.4 BN
Sex Horm Binding Glob, Serum 21.3 nmol/L 16.5-55.9 BN
After about 2-3 years of attempting to bring my test levels back to norm with no success - (SERMS, herbs, diet, fats/cholesterol, stress reduction, cold showers, sex, you name it)... my highest lab came in about 380 TT, 5 FT, 17 E2 . After 2 years of testing low and feeling like **** I made the decision to jump on the bandwagon. Multiple labs and temporary SERM responses indicated secondary hypogonadism, as my LH/FSH was consistently on the low end ~1 without any outside help.
Anyways, skipping forward - I have connected with a doc and compounding pharmacy that has prescribed me the Cyp/HCG/Arimidex. Lab results below were @ 25mg Cyp EOD, 100iu HCG ED, and .25mg Arimidex EOD. I got labs primarily because I felt I tanked E2 - joints hurt, mood took a nose dive... seems that was the case. So in terms of AI, I'm planning on moving the Arimidex to E3-4D gauging libido/joints as indicator of dosing frequency.
My question to you guys are the other flags noted below in bold (BUN, Creatinine, A/G ratio, and Hemocrit... as well as Cortisol/DHEA)
Can low estrogen cause a significant enough state of dehydration to contribute to the BUN/Creatinine/A/G/Hemocrit? I realize hemocrit levels are going to rise some on injectable, as I'm headed to give blood this week. But I was really hoping I could avoid this - now I'm considering bringing Cyp down to 20mg EOD, or even 10mg ED SC along with HCG. Also, pre-treatment Hemocrit levels stayed between 46-48. Any thoughts?
In terms of the Cortisol/DHEA - This was an AM - fasted bloodwork, so cortisol is not too much of a concern - as I realize it fluctuates and multiple testing should be considered. The DHEA however, seems on the low end from what I've been learning. I've also read some studies mentioning DHEA may lower cortisol levels over a period of time. I was thinking about starting low (say 15mg 2xday), and then gauging how I feel. Any one care to share their experiences with DHEA?
Everything else seems to look pretty good for initial lab results, correct me if you think otherwise. Any input would be greatly appreciated. Thanks
BUN 25 High mg/dL 6-20 BN
Creatinine, Serum 1.35 High mg/dL 0.76-1.27 BN
Albumin, Serum 4.6 g/dL 3.5-5.5 BN
Globulin, Total 1.7 g/dL 1.5-4.5 BN
A/G Ratio 2.7 High 1.1-2.5 BN
Cholesterol, Total 128 mg/dL 100-199 BN
Triglycerides 55 mg/dL 0-149 BN
HDL Cholesterol 47 mg/dL >39 BN
VLDL Cholesterol Cal 11 mg/dL 5-40 BN
LDL Cholesterol Calc 70 mg/dL 0-99 BN
T. Chol/HDL Ratio 2.7 ratio units 0.0-5.0 BN
WBC 6.8 x10E3/uL 3.4-10.8 BN
RBC 5.41 x10E6/uL 4.14-5.80 BN
Hemoglobin 17.2 g/dL 12.6-17.7 BN
Hematocrit 50.1 % 37.5-51.0 BN
Testosterone, Serum 1110 ng/dL 348-1197 BN
Free Testosterone(Direct) 44.0 High pg/mL 9.3-26.5 BN
Pregnenolone, MS 139 ng/dL ES
Dihydrotestosterone 77 ng/dL ES
T4,Free(Direct) 1.22 ng/dL 0.82-1.77 BN
DHEA-Sulfate 151.3 ug/dL 138.5-475.2 BN
Cortisol 20.6 High ug/dL 2.3-19.4 BN
TSH 1.530 uIU/mL 0.450-4.500 BN
Estradiol 13.3 pg/mL 7.6-42.6 BN
Prostate Specific Ag, Serum 0.6 ng/mL 0.0-4.0 BN
Triiodothyronine,Free,Serum 2.8 pg/mL 2.0-4.4 BN
Sex Horm Binding Glob, Serum 21.3 nmol/L 16.5-55.9 BN