Arimidex

AAA

New member
My dr. wants me to take Arimidex. My estradiol is high. Has anyone out there experienced any side effects while on this? Any imput at all? Thanks..........
 
AAA said:
My dr. wants me to take Arimidex. My estradiol is high. Has anyone out there experienced any side effects while on this? Any imput at all? Thanks..........
Click to expand...

I have used it in the past (1 pill twice a week) and experienced no side effects.
 
Dr. John said:
In that ALL drugs do are side effects, any GOOD side effects?
Click to expand...

Little blue pills keep you acting like the energizer bunny and "keep you going and going", but you might blow a valve. if some guy is going to keel over might as go out with smile on ones face right
 
Dr. John said:
They may not be quite sure what killed him, but it'd take a week to get the smile off his face!
Click to expand...
Recend incidence, 90+ died while dancing.
Second best way to die.
Invalid Link Removed
--------------------------
I have a class tonight with the one in white dress, 9-11:30PM EST.
 
If i am going to die last thing I would want to be would be falling a sleep in a chair. If I die I want it to be something I enjoy doing and and goto my grave with a big ronald mcdonald smirk on my face! Be sitting there in my coffin with a big azz grin making people wonder "He must have been really enjoying himself those final moments" I be looking down from above saying "you had no freaken clue"
 
hardasnails1973 said:
If i am going to die last thing I would want to be would be falling a sleep in a chair. If I die I want it to be something I enjoy doing and and goto my grave with a big ronald mcdonald smirk on my face! Be sitting there in my coffin with a big azz grin making people wonder "He must have been really enjoying himself those final moments" I be looking down from above saying "you had no freaken clue"
Click to expand...
OTOH, had I know as much as I know now about thyroid and adrenals I would have held my Mother couple more years.
She had temperature 95.3F for long time and nobody did anything. She died 95 yo. I have loked at the thermometer, had all I need in front of me.
---------------------------------------------------------
I really appreciate what I have learned here (and meso bd) in relatively short time.

Lets get the discussion rolling, hopefully doctors will chime in with cutting edge information.
 
uote:
Originally Posted by JanSz
Starlight Dance Center | Welcome
--------------------------
I have a class tonight with the one in white dress, 9-11:30PM EST.


Dr. John said:
Please tell her THAT would get me out there on the floor!
Click to expand...

No problemo, anytime you are in the area, she owns the place.
About $95/hr
but she may have a different price after her hormones are adjusted.
You may want to take a look at her resume:
under Katharina Marks
Invalid Link Removed
=============================================
back to the earth, wake up:
ps. how to go about women hormones?
is there a board similar to this one.
Some of us have wifes or SO of opposite sex.
 
Dr. John said:
I'll be happy to take her $95 for an hour of dancing with me.
Click to expand...
I would not rule that out.
Women do all kind of things after they are properly adjusted.
 
hardasnails1973 said:
Little blue pills keep you acting like the energizer bunny and "keep you going and going", but you might blow a valve. if some guy is going to keel over might as go out with smile on ones face right
Click to expand...

I took Viagra once. It got stuck in my throat and I had a stiff neck for weeks.
 
AAA said:
My dr. wants me to take Arimidex. My estradiol is high. Has anyone out there experienced any side effects while on this? Any imput at all? Thanks..........
Click to expand...
Yes you can bring your Estradiol down to low and kill your libido and get some bad ED. Start with 1/4 of a one mg. pill and take it every 3 days if you lose you libido or can get it up you are going to low stop taking it until things come back then go back on it but go to every 5 days.
Phil
 
pmgamer18 said:
Yes you can bring your Estradiol down to low and kill your libido and get some bad ED. Start with 1/4 of a one mg. pill and take it every 3 days if you lose you libido or can get it up you are going to low stop taking it until things come back then go back on it but go to every 5 days.
Phil
Click to expand...


Also i finding out that if you have high estrodiol you can also suspect that adrenal imbalnaces are also involved in there as well as liver detoxification problems to some degree.

Dr john notiifed in one thread that half life is 5 days of armidex I found that interesting :) Here is a question
Hypothetically if you took armidex then what day would be optima to test for estrogen levels. For example if you took it before blood test along with testosterone creme would this some how skew the test.

Phil when did you feel differnce from isocort to the HC was it almost instantaneous from 20 mgs of iscort to 20 mgs of HC
Thanks
 
pmgamer18 said:
Yes you can bring your Estradiol down to low and kill your libido and get some bad ED. Start with 1/4 of a one mg. pill and take it every 3 days if you lose you libido or can get it up you are going to low stop taking it until things come back then go back on it but go to every 5 days.
Phil
Click to expand...


Also i finding out that if you have high estrodiol you can also suspect that adrenal imbalnaces are also involved in there as well as liver detoxification problems to some degree.

Dr john notiifed in one thread that half life is 5 days of armidex I found that interesting :) Here is a question
Hypothetically if you took armidex then what day would be optima to test for estrogen levels. For example if you took it before blood test along with testosterone creme would this some how skew the test.

Phil when did you feel differnce from isocort to the HC was it almost instantaneous from 20 mgs of iscort to 20 mgs of HC
Thanks
 
hardasnails1973 said:
Also i finding out that if you have high estrodiol you can also suspect that adrenal imbalnaces are also involved in there as well as liver detoxification problems to some degree.

Dr john notiifed in one thread that half life is 5 days of armidex I found that interesting :) Here is a question
Hypothetically if you took armidex then what day would be optima to test for estrogen levels. For example if you took it before blood test along with testosterone creme would this some how skew the test.

Phil when did you feel differnce from isocort to the HC was it almost instantaneous from 20 mgs of iscort to 20 mgs of HC
Thanks
Click to expand...

I am not Phil, but my take is:

Dr John said:
"But to answer your question about AI timing, you cannot take an AI at some particular time, and get a synchronized result. It takes time to build up (2.5 half-lives) stable serum levels of a drug. The estrogen production you inhibit with this dose is the estrogen you will produce tomorrow. NOT from the concurrently taken DHEA.

Arimidex has a half-life of about 5 days."
================
When testing you want to be stabilized, otherwise waste of blood and money.
That happens after
2.5 half lives x 5days=12.5 days
 
A lot of his Adrenal and Thyriod stuff is new to me yet I have been into learing a lot in the last yr. I feel Isocort one pill may will = 2.5 mgs of Cortisol but 2 pill of Isocort =ing 5mgs of Cortisol do not = 5 mgs. of Cortef Cortef is stronger I seen this in my charting of my temps. I went from up and down to leveled now my temps are 98.5 to 98.7 doing them 3 times a day and taking the avg. Also we have no Idea what other hormones are in Isocort. As for taking Arimidex I can't say never looked at like this. When I was very high about 90 I tried to get it down doing .5 mgs every other day after 4 weeks tests showed it did not move. So we did .5 mgs everyday and it came down to 24 on my next 4 week test. At this time we went back down to .5mgs EOD and in 4 weeks I was to low but we did a test that only went down to 20 and the test came back <20. My Dr. cut the does to .5 mgs every 5 days in 4 weeks same thing <20 and I felt like crap. So we stopped for 6 weeks and my levels came back up to 46 then we did .25 mgs every 5 days this still made me to low.

Now at the time I was on Testim 10 grams with levels of less then 600 and I was house bound with a lot of joint and muscle pain. I heard about Indolplex/DIM and went on this wow in less then a week I felt great I got my moring wood back after 35yrs. on not having them. I started at one tablet at dinner time and ended up at one half a tablet to stay in the Zone. Still I was sore and had a hard time just waking.

I found Invalid Link Removed and read TRT: A Recipe for Success and the HCG Update. Got my Dr. to drop the gels and went on shots ended up at 150mgs a week and my pain was going I was out walking and even started back at the GYM 3 days a week. Now we added HCG and my levels doubled man I never felt this good now my Total and Free T levels were up into the upper 1/3 of my labs range. Hell I felt like I did when I was 20. But the DIM was not keeping up with the E2 and I had to go back on Arimidex to keep it down.

So for me I feel better and have no pain doing more T with HCG. And I feel it is a small price to pay to have to have take arimidex to keep my E2 in check.

Phil
hardasnails1973 said:
Also i finding out that if you have high estrodiol you can also suspect that adrenal imbalnaces are also involved in there as well as liver detoxification problems to some degree.

Dr john notiifed in one thread that half life is 5 days of armidex I found that interesting :) Here is a question
Hypothetically if you took armidex then what day would be optima to test for estrogen levels. For example if you took it before blood test along with testosterone creme would this some how skew the test.

Phil when did you feel differnce from isocort to the HC was it almost instantaneous from 20 mgs of iscort to 20 mgs of HC
Thanks
Click to expand...
 
pmgamer18 said:
A lot of his Adrenal and Thyriod stuff is new to me yet I have been into learing a lot in the last yr. I feel Isocort one pill may will = 2.5 mgs of Cortisol but 2 pill of Isocort =ing 5mgs of Cortisol do not = 5 mgs. of Cortef Cortef is stronger I seen this in my charting of my temps. I went from up and down to leveled now my temps are 98.5 to 98.7 doing them 3 times a day and taking the avg. Also we have no Idea what other hormones are in Isocort. As for taking Arimidex I can't say never looked at like this. When I was very high about 90 I tried to get it down doing .5 mgs every other day after 4 weeks tests showed it did not move. So we did .5 mgs everyday and it came down to 24 on my next 4 week test. At this time we went back down to .5mgs EOD and in 4 weeks I was to low but we did a test that only went down to 20 and the test came back <20. My Dr. cut the does to .5 mgs every 5 days in 4 weeks same thing <20 and I felt like crap. So we stopped for 6 weeks and my levels came back up to 46 then we did .25 mgs every 5 days this still made me to low.

Now at the time I was on Testim 10 grams with levels of less then 600 and I was house bound with a lot of joint and muscle pain. I heard about Indolplex/DIM and went on this wow in less then a week I felt great I got my moring wood back after 35yrs. on not having them. I started at one tablet at dinner time and ended up at one half a tablet to stay in the Zone. Still I was sore and had a hard time just waking.

I found Invalid Link Removed and read TRT: A Recipe for Success and the HCG Update. Got my Dr. to drop the gels and went on shots ended up at 150mgs a week and my pain was going I was out walking and even started back at the GYM 3 days a week. Now we added HCG and my levels doubled man I never felt this good now my Total and Free T levels were up into the upper 1/3 of my labs range. Hell I felt like I did when I was 20. But the DIM was not keeping up with the E2 and I had to go back on Arimidex to keep it down.

So for me I feel better and have no pain doing more T with HCG. And I feel it is a small price to pay to have to have take arimidex to keep my E2 in check.



Phil
Click to expand...
Phil may be you feel so much better maybe cause it may have not been the estrodial that the problem, but rather the excess of bad estrogen building up and that was bogging down your liver pathways. Also to if you are low on good bacteria it will also increase the Bad estrogen (not referring estrodial) because the bacteria is one of the main resource of estrogen metabolism via congugation. This may explain why you responded to DIM so good because your oh-16 (bad estrogen ) was out of balance with the good estrogen, Have you ever had that checked via urine to find out. I am sure it be interesting to see the ratio between the two. People forget have intestinal bacteria is so important for the human body and is over looked as a main source of estrogen congugation. So it might not be a bad idea to get a comprehensive stool sample done to see how low your bifidiobacteria are because this may be a major player in resolution to your problem that has gone over looked. Again you may be only treated the symptoms of the problem rathr then the root cause which is dybiosis of the bowel. I can pretty much guaraantee you there are flora imbalances in your gut that by solving them could reduce stres of body to deal with estrogen.
 
ECTOmorph said:
what is a normal dose protocal of arimidex

.25 - .50? And is that every day, every other day, or every three days?
Click to expand...

Too many factors play into this and needs to be under trained medical advice and not self administered because it can alters others hormones. For now might want to look into DIM and increasing fiber intake to help elminate extra estrogen
 
ECTOmorph said:
what is a normal dose protocal of arimidex

.25 - .50? And is that every day, every other day, or every three days?
Click to expand...
If after a test your very high then try .5mgs every otherday then when you lower go to .25mgs every 3 days to keep it down but not to low.
Phil
 
pmgamer18 said:
If after a test your very high then try .5mgs every otherday then when you lower go to .25mgs every 3 days to keep it down but not to low.
Phil
Click to expand...

Phil how soon does your levels actually drop and be tested after starting armidex 2-3 weeks
 
I remember doing a stool test 2 yrs. ago my Dr. has done every test under the sun but I will ask if this was checked. My Total E's are normal not high in mid range but this is a blood test.
Phil
hardasnails1973 said:
Phil may be you feel so much better maybe cause it may have not been the estrodial that the problem, but rather the excess of bad estrogen building up and that was bogging down your liver pathways. Also to if you are low on good bacteria it will also increase the Bad estrogen (not referring estrodial) because the bacteria is one of the main resource of estrogen metabolism via congugation. This may explain why you responded to DIM so good because your oh-16 (bad estrogen ) was out of balance with the good estrogen, Have you ever had that checked via urine to find out. I am sure it be interesting to see the ratio between the two. People forget have intestinal bacteria is so important for the human body and is over looked as a main source of estrogen congugation. So it might not be a bad idea to get a comprehensive stool sample done to see how low your bifidiobacteria are because this may be a major player in resolution to your problem that has gone over looked. Again you may be only treated the symptoms of the problem rathr then the root cause which is dybiosis of the bowel. I can pretty much guaraantee you there are flora imbalances in your gut that by solving them could reduce stres of body to deal with estrogen.
Click to expand...
 
Run organic acids with amino urinalyisis and may be a copper serum and ceruoplasm be good too. Estrogen causes copper to build up in liver and serum copper will be low normal. it happened to me. This is indication of severe adrenal fatigue
 
pmgamer18 said:
A lot of his Adrenal and Thyriod stuff is new to me yet I have been into learing a lot in the last yr. I feel Isocort one pill may will = 2.5 mgs of Cortisol but 2 pill of Isocort =ing 5mgs of Cortisol do not = 5 mgs. of Cortef Cortef is stronger I seen this in my charting of my temps. I went from up and down to leveled now my temps are 98.5 to 98.7 doing them 3 times a day and taking the avg. Also we have no Idea what other hormones are in Isocort. As for taking Arimidex I can't say never looked at like this. When I was very high about 90 I tried to get it down doing .5 mgs every other day after 4 weeks tests showed it did not move. So we did .5 mgs everyday and it came down to 24 on my next 4 week test. At this time we went back down to .5mgs EOD and in 4 weeks I was to low but we did a test that only went down to 20 and the test came back <20. My Dr. cut the does to .5 mgs every 5 days in 4 weeks same thing <20 and I felt like crap. So we stopped for 6 weeks and my levels came back up to 46 then we did .25 mgs every 5 days this still made me to low.

Now at the time I was on Testim 10 grams with levels of less then 600 and I was house bound with a lot of joint and muscle pain. I heard about Indolplex/DIM and went on this wow in less then a week I felt great I got my moring wood back after 35yrs. on not having them. I started at one tablet at dinner time and ended up at one half a tablet to stay in the Zone. Still I was sore and had a hard time just waking.

I found Invalid Link Removed and read TRT: A Recipe for Success and the HCG Update. Got my Dr. to drop the gels and went on shots ended up at 150mgs a week and my pain was going I was out walking and even started back at the GYM 3 days a week. Now we added HCG and my levels doubled man I never felt this good now my Total and Free T levels were up into the upper 1/3 of my labs range. Hell I felt like I did when I was 20. But the DIM was not keeping up with the E2 and I had to go back on Arimidex to keep it down.

So for me I feel better and have no pain doing more T with HCG. And I feel it is a small price to pay to have to have take arimidex to keep my E2 in check.

Phil
Click to expand...
Somewhere recently I think I have seen Dr John saying that when TRT is properly done it causes minimal E2 and DHT problems.
He never discussed details of that idea.
After going thru my recent research on mathematcs of
TT, Albumin and SHBG and how that afects FreeT and BAT,
I am comming to conclusion that much more effort should be placed on lovering of SHBG.
With you boys supported by HCG you may end up with allmost all T that you need to have decent FreeT and BAT.
.
.
 
Dr. John is right I know a lot of guys that don't need higher levels of T and don't have a e2 problem. What math are you talking about do you know something I don't fill me in I am a retired Engineer and math is my game.
Phil
 
pmgamer18 said:
Dr. John is right I know a lot of guys that don't need higher levels of T and don't have a e2 problem. What math are you talking about do you know something I don't fill me in I am a retired Engineer and math is my game.
Phil
Click to expand...
For example one is here.
http://anabolicminds.com/forum/male-anti-aging/57655-free-testosterone-albumin.html
01-14-2007, 01:24 PM
and latter posts

also here
Invalid Link Removed
==============================
The idea is, (supported by references within those links):
most laboratories do FreeT and BAT blood assays using all kind of methods, they are all wrong.
The right way to do it is by calculation, using this reference from Free Testosterone calculator
“J Clin Endocrinol Metab 84:3666-3672, 1999 – A critical evaluation of simple methods for the estimation of free testosterone in serum”
QuestDiagnostic uses that method.
So one does not have to look at individual reference ranges for
TT, albumin and SHBG because that muddy the picture.
Go straight to FreeT and BAT and see where you are.
Usually, before you want to shoot T and screw up your estrogens and DHT the better way may be to put emphasis on the other parts of the equations.
Lower SHBG,
control estrogens
get DHEA in high range
Adrenals, thyroid
get HCG to get more of natural T
and as a last resort add T but only the neccesary minimum.
Go slow. Wait between changes so the body have a time to stabilize.
Probably month or month and half.
Remember from previous Arimidex discussion
it takes 2.5 half life for stabilization to happen,
often that is very long time.
============================================
Actually there is 2006 paper with calculations for FreeT and BAT that is even more up to date,
since you are good with numbers you may want to look at it and translate it to a friendly calculator that we could all use.
On a second page of free testosterone calculator they show how it is done per the 1999 paper.
.
.
 
Ok it's not new for me but will help the others.
Phil
JanSz said:
For example one is here.
http://anabolicminds.com/forum/male-anti-aging/57655-free-testosterone-albumin.html
01-14-2007, 01:24 PM
and latter posts

also here
Invalid Link Removed
==============================
The idea is, (supported by references within those links):
most laboratories do FreeT and BAT blood assays using all kind of methods, they are all wrong.
The right way to do it is by calculation, using this reference from Free Testosterone calculator
“J Clin Endocrinol Metab 84:3666-3672, 1999 – A critical evaluation of simple methods for the estimation of free testosterone in serum”
QuestDiagnostic uses that method.
So one does not have to look at individual reference ranges for
TT, albumin and SHBG because that muddy the picture.
Go straight to FreeT and BAT and see where you are.
Usually, before you want to shoot T and screw up your estrogens and DHT the better way may be to put emphasis on the other parts of the equations.
Lower SHBG,
control estrogens
get DHEA in high range
Adrenals, thyroid
get HCG to get more of natural T
and as a last resort add T but only the neccesary minimum.
Go slow. Wait between changes so the body have a time to stabilize.
Probably month or month and half.
Remember from previous Arimidex discussion
it takes 2.5 half life for stabilization to happen,
often that is very long time.
============================================
Actually there is 2006 paper with calculations for FreeT and BAT that is even more up to date,
since you are good with numbers you may want to look at it and translate it to a friendly calculator that we could all use.
On a second page of free testosterone calculator they show how it is done per the 1999 paper.
.
.
Click to expand...
 
pmgamer18 said:
Ok it's not new for me but will help the others.
Phil
Click to expand...
I am really glad to hear that.
At this stage of the game I am mostly interested in this 2006 paper
-------http://www.atypon-link.com/WDG/doi/pdf/10.1515/JLM.2006.050]
and how to use it to do actual number crunching the way I would do it with this:
Invalid Link Removed

If you could help me with it, that would be great.
 
JanSz said:
I am really glad to hear that.
At this stage of the game I am mostly interested in this 2006 paper
-------http://www.atypon-link.com/WDG/doi/pdf/10.1515/JLM.2006.050]
and how to use it to do actual number crunching the way I would do it with this:
Invalid Link Removed

If you could help me with it, that would be great.
Click to expand...
But you see I input numbers into this link and I have see it before I have my lab numbers and they are not the same as the calculator. Also what does bioablilable do for you when you on TRT.
To many times men get hung up on labs and feel something is wrong because of them yet they feel fine.
Phil
Phil
 
pmgamer18 said:
But you see I input numbers into this link and I have see it before I have my lab numbers and they are not the same as the calculator. Also what does bioablilable do for you when you on TRT.
To many times men get hung up on labs and feel something is wrong because of them yet they feel fine.
Phil
Phil
Click to expand...
That is the whole point, your lab numbers for FreeT and BAT are most likely wrong, unles done by Quest Diagnostic or probably few other labs.
Read this, he explains why it is wrong:
Invalid Link Removed

The LabCorp who is doing my blood tests is on the wrong side also, that is why I am switching to Quest Diagnostics when I will do my next tests.
===================================
FreeT and BAT are the only T that works for us.
The T bounded by SHBG does nothing.
So knowing TotalT do not gives us much of usefull information.
.
 
JanSz said:
That is the whole point, your lab numbers for FreeT and BAT are most likely wrong, unles done by Quest Diagnostic or probably few other labs.
Read this, he explains why it is wrong:
Invalid Link Removed

The LabCorp who is doing my blood tests is on the wrong side also, that is why I am switching to Quest Diagnostics when I will do my next tests.
===================================
FreeT and BAT are the only T that works for us.
The T bounded by SHBG does nothing.
So knowing TotalT do not gives us much of usefull information.
.
Click to expand...
The labs were Quest still what does it matter if your on TRT.
Best to dose is Total T. Even Free T tells you very little on TRT.
You quote LEF a lot are you a rep for them and pushing it on us.
Phil
Phil
 
hardasnails1973 said:
Phil may be you feel so much better maybe cause it may have not been the estrodial that the problem, but rather the excess of bad estrogen building up and that was bogging down your liver pathways. Also to if you are low on good bacteria it will also increase the Bad estrogen (not referring estrodial) because the bacteria is one of the main resource of estrogen metabolism via congugation. This may explain why you responded to DIM so good because your oh-16 (bad estrogen ) was out of balance with the good estrogen, Have you ever had that checked via urine to find out. I am sure it be interesting to see the ratio between the two. People forget have intestinal bacteria is so important for the human body and is over looked as a main source of estrogen congugation. So it might not be a bad idea to get a comprehensive stool sample done to see how low your bifidiobacteria are because this may be a major player in resolution to your problem that has gone over looked. Again you may be only treated the symptoms of the problem rathr then the root cause which is dybiosis of the bowel. I can pretty much guaraantee you there are flora imbalances in your gut that by solving them could reduce stres of body to deal with estrogen.
Click to expand...

I just thought i would agree with you on the importance of gut health. Ever since i started taking probiotics and eating yogurt everyday i never get heartburn or indigestion anymore and my bowel function is slightly improved. Gut bacteria and health is way overlooked IMO.
 
pmgamer18 said:
The labs were Quest still what does it matter if your on TRT.
Best to dose is Total T. Even Free T tells you very little on TRT.
You quote LEF a lot are you a rep for them and pushing it on us.Phil
Phil
Click to expand...
Please do not feel pushed, I am not a rep, just satisfied user.
I got my first comprehensive education from their protocols.
Some of them are in stickies and frequently quotet by others.
I also wish that they got more dedicated advisors.
 
Dr. John said:
It's hard to believe I was once an Honors Calculus student (while rest of my Pre-Med mates were lolly-gagging through "Practical Calc"). Since they put those two letters in front of my name, I can hardly add and subtract!

He went through some projections with respect to varying levels of hormones via SHBG delta. Nice effort, as I explained, but it doesn't really work that way.
Click to expand...
Your dam good at what you do and most Dr.'s can't read labs or ranges. I have been giving guys this link to show there Dr.'s that tell them there in the normal range when one is low normal.
Invalid Link Removed
Phil
 
pmgamer18 said:
Your dam good at what you do and most Dr.'s can't read labs or ranges. I have been giving guys this link to show there Dr.'s that tell them there in the normal range when one is low normal.
Invalid Link Removed
Phil
Click to expand...

How about this one programmer in 1991 the scale for ft4 was .9 on the lower end 10 years later they decreased it to .8. I still think these lab ranges are a conspiracy for not treating people when they need to be. Its like they are just waiting for you to fall off the cliff before they even considered treatment. Wth a serum testosterone of 40 my dr told me I was just a little low. I left the office and was :wtf: I have to show people the blood work to proof that it came out that way. That readin was 2 months after being infected by food poisining probably due to elevated cortisol from dealing with strress of the infection
 
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