Anabolic Phytonutrient & Muscle Builder
Novel Muscle Building Supplement
Novel Muscle Building Supplement
200 Mg. Apigenin (as ApiPure™)
25 Mg. AstraGin®
5 mg. Bioperine®
18,000 Mg. (18 Grams) Apigenin Per Bottle
Api-Plex Highlights/Supports:
- Lean Muscle & Strength Gains
- Increases in Stamina & Endurance
- Novel Muscle Building Supplement
- Anabolic & Anti-Catabolic Properties
- Non-Hormonal – Suitable for Men & Women
- Bodybuilding, Athletic, General Health, Longevity, & Anti-Aging Benefits
- Ultra-Potent 200 mg. Per Capsule
- Do you want to build lean muscle and strength?
- Do you want to improve body-composition and workout performance?
- Do you like the idea of supplementing with an ingredient that has so many potential benefits that a series of articles could be written about it?
The quest for muscle and performance gains has led researchers for years to look for natural compounds that can enhance muscle protein synthesis, boost muscle growth, enhance recovery, and improve performance. Over the years, scientists have come across a number of exciting natural anabolic compounds, but rarely one that has such a broad range of potential benefits as Apigenin.
Apigenin Potential Muscle Building & Performance Enhancing Highlights/Supports:
- Lean Muscle & Strength
- Improved Workout Performance
- Increases in Stamina & Endurance
- Increased Protein Synthesis
- Improved Insulin Resistance
- Supports Cortisol Modulation
- Enhanced IGF-1 and IGF-2 Levels
- Anabolic & Anti-Catabolic Properties
- Potential Anti-Aromatase/Anti-Estrogenic Properties
- & More
- Positive Mood
- Prostate Health
- Blood Pressure Support
- Cardiovascular Health
- Anti-inflammatory Support
- Improved Insulin Resistance
- Positive Effects on Autophagy
- Improved Sense of Well-Being
- Neuroprotective & Cardioprotective Properties
- Numerous Potential Anti-Aging & Longevity Benefits
- & More
Api-Plex
For Those That Want to….
Maximize Every Possible Bit of Their Natural Muscle Growth Potential
For Those That Want to….
Maximize Every Possible Bit of Their Natural Muscle Growth Potential
What is Apigenin?
Apigenin is a natural flavonoid found in parsley, celery, chamomile, and citrus fruits that is similar to Quercetin, Hesperidin, Luteolin, and Kaempferol. However, even though its structure is very similar to these compounds, Apigenin has some very different effects in the body than those related substances.
Apigenin has a natural anabolic effect, as first discovered by researchers at the Korea Food Research Institute.
In the initial study that led to Apigenin’s popularity for building muscle, scientists began experimenting with his flavone with mice and the mice receiving the Apigenin had significant muscle mass gains over the mice not receiving it. The greater the dosage of Apigenin the mice took, the larger the quad increase!
Apigenin, even before the research showing its natural anabolic benefits, was already regarded as a very exciting compound due to its wide variety of overall benefits including its anti-inflammatory benefits as well as its potential prostate, neuroprotective, and cardioprotective properties. However, of particular interest to many researchers is Apigenin’s potential anti-cancer benefits, which have made Apigenin the subject of many studies around the world.
Another very exciting aspect of Apigenin is its ability to enhance autophagy. Autophagy is a natural cellular mechanism by which by which the cells in our body degrade unnecessary or damaged components within the cell. The process of autophagy helps maintain normal functioning (homeostasis) in the cell. (If you’re familiar with what defragging a computer means, think of that as a good comedic analogy to this process by the cells).
Apigenin has also been studied for a wide variety of other potential benefits including its anti-inflammatory, antioxidant, anti-aromatase, cardiovascular, and antibacterial properties, and more.
Muscle Building, Longevity, Anti-Aging Properties, & More
What are flavones/flavonoids?Flavonoids/flavones are bioactive compounds in plants that exert a wide range of biological effects. They fulfill many different functions in plants and the ones in Apigenin have been shown to offer a wide range of potential beneficial effects, including beneficial effects on improved athletic performance and helping to build and preserve muscle tissue.
Apigenin Study Relating to Muscle Growth and Performance Enhancement:
Scientists at the Korea Food Research Institute began experimenting with Apigenin in mice and found that the mice receiving Apigenin had significant muscle mass gains of the mice not receiving it.
This study was split into a control group, a lower dose Apigenin group, and a higher dose Apigenin group. Researchers observed that the greater the dose of Apigenin that the mice took, the larger the quadriceps increase.
The estimated human equivalent to the dosages used in these studies were 20 mg. for the lower dosage group and 40 mg. for the higher dosage group.
There were a number of mechanisms of action noted in the studies, including:
- Apigenin increased the production of contractile muscle protein (MHC).
- Increases in the anabolic hormones IGF-1 and IGF-2.
- Increases in PGC-1-alpha, a signal molecule that stimulates cells to manufacture more mitochondria.
- Triggering of anabolic pathways by activating the enzyme protein arginine methyltransferase-7 (Prmt7) – shown after in vitro research with C2C12 muscle cells.
- “We found that apigenin increases quadriceps muscle weight in mice and increases their running distance on an accelerating treadmill.”
- “These events are attributable to upregulation of the Prmt7-PGC-1-alpha-GPR56 signaling pathway.”
- “We also found that apigenin induces myogenic differentiation by regulating Prmt7-p38-myoD and the Akt-S6K1 pathway in C2C12 cells.”
- “These results suggest that apigenin could be used as a functional food to prevent muscle loss and enhance muscle function.”
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