Why do the ultrasensitive test when many ,or this poster's Doctor, may not be familiar with the numbers from the test and how to react to those? Look what happened to hardasnails when he had that test and his Doctor saw the low number and took him off of Arimidex and then hardasnails went through a few weeks of estrogen poisoning and had levels over 70pg/ml. Hardasnails' brain was frying in estrogen. His typical detailed posts became incompressible and he could not type very well that means that is motor system was also affected.
So we have an example of that test leading to patient harm.
Why is the ultrasensitive E2 test the correct test and why is the basic E2 test incorrect? I think that most TRT where E2 is getting tested is the basic E2 test and that most of the experience in dealing with E2 is via experience gained with the basic E2 test. If E2 is at a certain level via a basic E2 test and then one uses AI to lower E2 and a basic test shows a lower level of E2 in response to the AI; what is the problem with that?
I could probably do some hand waving but that would not convince anyone.
Lets check what good Dr John have to say about it:
Invalid Link Removed
Quote:
Estradiol (specify the Extraction Method, or “sensitive” assay for males)
=========================
As for handwaving.
Invalid Link Removed
page 64
men (10-50)
women (150-750) (there are other smaller ranges)
Men have less Estrodial, require more accurate method to find out the actual level.
There are probably other reasons.
===========================
In one of my previous post I convinced myself about uselesness of using BioAvailable Testosterone calculator.
It is due to
totally incosistent error pattern.
It would help if people could tested Estrodial twice.
Once the right way and the other, the less accurate way.
We would have more evidence.
I happen to have such a test from one blood draw.
Estradiol 45 pg/mL (<52) 1-45/52= 0.13 (from top)
Estradiol, Ultra-sensitive 27 pg/mL (10-50) 1-27/(50-10)= 0.33(from top)
If estrodial results are somewhat similar to BAT behaviour there will be no way to estimate ultrasensitive range knowing less accurate range.
----------------------------------------------------------------------------------------------------
I always think that it is because english is my second language so I never dared to make this type of a coment.
I hope Hardasnails' will take it the way it is ment, us being concern about fellow brother in suffering.
I also have noted Hardasnails' problem.
Some posts are clear as a bell, very educational, some are far from it.
Hard to say if it is due to estrogen overload or something else,
wish someone with more knowledge say few words about it.
More importantly, one being in state like that, have a poor chance at convicting a doctor of the paramount importance of proper estrodial or other test.
=============================================
