Injectable yohimbine hcl and clen aka "Helios" who's done it?

  1. Injectable yohimbine hcl and clen aka "Helios" who's done it?


    Title states it all, looking for personal experiences with this injectable combo pushed by the late great dan duchaine.

    I originally posted in the aas section but thought it'd be better here.

    A side note, eviscerate an clen rubbed on aren't the same thing, especially since they took the aminophylene out, which makes it mediocre imo.

    Go Clemson.


  2. Doing it now second cycle with it
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  3. I'm doing oral clen/yohimbine now, great results, don't see how injecting would increase localised fat loss but I'm in too see if anyone thinks it does and why!

  4. Definitely spot is great. My love handles are showing changes

  5. Quote Originally Posted by Juicedeez utz View Post
    I'm doing oral clen/yohimbine now, great results, don't see how injecting would increase localised fat loss but I'm in too see if anyone thinks it does and why!
    I read this article on it:
    Quote Originally Posted by Random site

    Helios was originally developed by an idea from the legendary body-building guru Dan Duchaine. Generic Supplements is selling this extremely potent solution on the bodybuilding market. The ingredients (Clenbuterol and Yohimbine HCL) are forbidden in almost every country, as well as administration via injection. This is only allowed by a doctor or medical trained nurse. But this form of administration is also the best way for spot reduction.

    The art of spot reduction.

    When you begin a diet, you may notice that you lose fat very unevenly on your body. The areas you don't wish to concentrate your fat loss seem to be most responsive to the restriction of calories. On the other hand, the areas you desire to shed fat seem to be unaffected by the diet. In women, the breasts may be shrinking, while the lower body remains as fat as it was. In men, even if the waist is getting smaller, the abs are not getting any more visible. Why put your body through a tough and often unhealthy diet if unwanted inches of fat remain? What we want is a specifically targeted fat loss, but we are told that spot reduction is impossible! Is this true?

    Rather than an overall and even fat reduction, the weight loss will be more "spot specific". Popular belief is that we can not spot reduce fat. This is however a myth, because the human body does, but unfortunately it doesn't necessarily do it in the places we wish it to. What we have to do, is to redirect the fat destruction in areas we want to shrink rather than everywhere else. Please realise that your abs are not covered by that much fat. Imagine if one could concentrate the fat loss exclusively in that particular area. It is the same thing for the women who could easily lose their lower body fat by strictly concentrating the fat reduction there.

    Best sites for application as mentioned above are the triceps, "love handles", thighs, gluteus and the "saddle bags" or waist (basically any area that has fat accumulation). These areas will vary from person to person, though the above listed are the most common. The fat that fails to disappear even through a strict diet is called "stubborn fat". Typically, so called stubborn fat is estrogenic by nature, however some people just have high numbers of A2 receptors. The A2 receptor is highly influenced by oestrogen if you are a women, and if you have estrogenic fat patterns you most likely have large numbers of A2 receptors.

    Yohimbine HCL

    The reason why 'Yohimbine hcl' is included in Helios is that it binds to the A2 receptor and blocks Norepinephrine(and other A2 agonist including oestrogen) from binding to, and antagonizing it (which inhibits the release of fatty acids). It thus allows for fatty acids to be "burned", hence the stubborn fat will be lost. These two ingredients, Yohimbine and clenbuterol , ‘speed up’ the metabolism of the injected area and provoke a chemical reaction that change fat cells into fatty acids, which will slip through cell membranes and into the bloodstream to be burned. If you don’t burn the freed fatty acids through a firm aerobic workout, your body will store them again in fatty deposits.


    Side effects which may occur are loss of appetite, tremors, dizziness, nervousness, restlessness, irregular heart beat, nausea, excessive sweating, diarrhoea and it is also possible to experience other complications due to the weight, or body fat percentage loss that results from its use.

    Why do we spot reduce upside down naturally?

    There are two main mediators of fat mobilization. One consists of the circulating hormones such as norepinephrine. They stumble upon fat stores by chance, and will do little to spot reduce. By using oral clenbuterol, we increase the circulation of those lipolytic factors, but we do not truly redirect spot reduction the way we wish to. The chances are, we accentuate the spot reduction in the wrong places. The second pathway is far more interesting. All our adipose stores are innervated by the nervous system a bit like our muscles are. In other words, our brain is directly related to each of our adipose depots. Through the nervous system, the brain can then send neurotransmitters in whatever depot it wishes. Those neurotransmitters (epinephrine and norepinephrine) happen to be the main direct lipolytic hormones. It means that potentially our brain possesses the ability to allow us to spot reduce at will, by sending fat loss mediators in very specific depots. The problem is we do not know how to redirect our brain efforts to help us spot reduce. This is why we spot reduce in the wrong areas: i.e. the places the brain local efforts are the most intense versus the places were it is the laziest.

    So, if the brain does not wish to send enough fat loss hormones to the specific areas we want to get rid of, we can do it ourselves by locally injecting those hormones. This way, we can redirect lipolysis where we wish to. It is now possible to spot reduce at will! Whenever I say this, people will get over excited, believing that a single subcutaneous injection will immediately destroy all the fat present. This is not the case as other anti-lipolytic forces are also at play to prevent that. But after a month of local injections plus a proper diet, you will clearly see that those formerly resistant areas are not as hard to get rid of as before. Fat loss will be more evenly distributed, which will indirectly spare muscle mass. In effect, with a classical diet, when you have lost most of your fat except that around the waist, what do you do? Diet harder which translates into an intense muscle cannibalization and a minimal eradication of the waist's fat. By using local injections, this classical suicidal period can be avoided.

    How to proceed?

    Idealistically, you have a training buddy or friend that wants to loose fat the same way. The first time you use Helios is comparable with the first time you used coffee. The active ingredient in coffee (caffeine) gives the same effects as clenbuterol, it makes you sweat, nervous and your heartbeat increases. This off course is dose dependant, and each individual will be different. Your body will quickly adapt to the use of Helios, and allow you to raise the used doses. Start with two to four shots with a very low dose (we suggest 40 iu - 0,4 ml) on the same place on the left- and right side of your body. If you handle it well, increase the dosages possibly through several shots spread locally over the fat area. This will allow you to cover a larger fat area with a single injection. The fat loss drugs are more evenly spread on the "to be destroyed" area. Try to hit different parts of the deposit each time so that every fat cell gets abbreviated with some adipose destructor. Ideally, this should be done first thing in the morning on an empty stomach before aerobic training. Once you are used to it, you can drink one or two cups of coffee between the injections and the aerobic workout. This will amplify the effect of the Helios. Understand that the injections will only force the local fat to leave its adipose reserve and to pass in the blood. Fat molecules have not been destroyed yet. The aerobic training has to take care of that (along with the help of the night time fast). Some also use appetite suppressants like Meridia or thyroid hormones.

    Go Clemson.
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  6. Sounds good

  7. Hmm actually sounds like it makes sense but studies would be better haha I'd still be willing to give it a go though! I can get something similar called elixir burn but it's got 25mg T3, 10mg albuterol and 10mg Y, which seems like a lot even for my high stim tolerance!! Gonna try find some Helios in the U.K. Now haha

  8. it seems Helios is 40mcg clen, 5mg yohimbine hcl

    Go Clemson.

  9. Didn't see this thread on my initial search.
    HELIOS...anyone try, opinions?

    Go Clemson.

  10. Quote Originally Posted by brofessorx View Post
    it seems Helios is 40mcg clen, 5mg yohimbine hcl
    Yeah I just found a bottle but for 34 for 10ml, I'm ok thanks

  11. Lol might be cheaper to buy vet grade injectable forms. Then you can control the dosing of clen.

    Go Clemson.

  12. Here's another article written by Mike arnold better explaining the science of injectable vs oral.

    Understanding Helios

    by Mike Arnold

    After receiving a question about Helios in one of my Q & A’s this last week, I started asking myself why more people don’t use this product. Despite being one of the most effective Clen preparations on the market, it gets relatively little fanfare, coming up in conversation only occasionally and typically in the form of an inquiry. This is a real shame, as Helios is not only a great overall fat loss aide, but has also earned its stripes as a legitimate spot reducer. Whether its failing popularity is due to a lack of availability, general ignorance about the drug, or other reasons, it is overdue for its fair share of time in the limelight.

    A combination of two routinely used fat loss agents; Helios is a mixture of 40 mcg Clenbuterol to 5 mg Yohimbine HCL, per ml. At first glance, there doesn’t seem to be anything special about this basic formulation, making it easy to question its overall appeal in comparison to traditional versions of these drugs. After all, one can more easily purchase them solo, allowing for individual dosing and bypassing the entire injection process. With these potential downsides (although sub-q injections are rarely a deal breaker for serious BB’rs), what is it that makes Helios worthwhile to the consumer?

    Due to the delivery method employed, the pharmacokinetics of the compounds within Helios is altered from that of its oral form. When consumed orally, Yohimbine-HCL is rapidly absorbed (11 min half life) and usually achieves maximum plasma concentration in less than one hour. However, the mean bioavailability is low (22–33%, depending on the studies referenced), with a high degree of variance from person to person, ranging from an absorption rat as little as a 4% to as high as 87%. Although dietary fat reduces the absorption rate, variability among individuals is still high regardless of nutritional status.

    In contrast, oral Clenbuterol has a half-life of about 35 hours, while achieving maximum plasma concentration within roughly 2.5 hours and lasting 6 hours. In terms of absorption rate, oral delivery has little impact on Clenbuterol relative to Yohimbine HCL. However, when assessing these 2 drugs as a whole, we see little consistency in absorption rates among individuals. This is particularly true with Yohimbine HCL, which is absorbed at less than 5% in some instances. Clearly, Yohimbine is at a significant disadvantage when consumed orally compared to intravenous or subcutaneous delivery, which boasts a near 100% absorption rate for both drugs.

    Those who have used Helios will attest to the increased potency of this combination when administered in injectable form, especially Yohimbine HCL. Among many, Yohimbine HCL is viewed more as an ancillary drug rather than an integral component of one’s fat loss protocol. Take it or leave it is frequently the general consensus. No doubt, this opinion is most often due to sub-optimal dosing practices. If the ideal dosing range is 10-12 mg’s daily, but the individual is only absorbing 25% of the drug, their true usable dose is only 2.5-3.0 mg’s daily; hardly enough to provide maximum results. What about those who end up at the bottom of the pack, absorbing only 4-5%? Well, they might as well not be using it at all. The bottom line is that Helios has superior bioavailability, making it the more potent product on a mg per mg basis.
    Generally speaking, I recommend that first time Helios users begin at about 50% of their normal starting dose, using Clenbuterol as a guide. So, if you would normally start out at 40 mcg per day, I suggest dropping down to only 20 mcg and gauging your response before going up. This may not seem like much to an experienced Clen user, but keep in mind that a disturbingly large percentage of the Clenbuterol sold on the UGL market today is moderately to severely under-dosed. With the addition of high-dose Yohimbine HCL at a near 100% absorption rate, the stimulant effect is further amplified. Finally, Helios hits much quicker than oral forms, so be prepared to feel maximum effects within minutes. Because of these differing pharmacokinetics, use caution when attempting to determine your ideal dose.

    Perhaps the most unique aspect of this product is its ability to spot reduce. Similar to growth hormone, Helios is well known for being able to breakdown bodyfat at the injection site. However, it would be a mistake to target the exact same injection site repeatedly, unless you prefer uneven fat loss in the form of divots and bumps. When injecting into larger fat deposits, such as the love handles, most choose to break up their daily dose into 6-8 micro-injects, with 3-4 injections per side. This will allow the compounds to reach a larger percentage of fat cells within the region, allowing for a more even distribution of fat loss. Many have reported bruising at the injection site, so take this into consideration if you have a significant other who is not aware of your drug habits, as it may be somewhat difficult to explain away the existence of scattered, chronic bruising. Of course, if spot rejection is not a concern, then a single injection at a location of your choosing will suffice, although I do recommend that your total daily dose be broken up into at least 2 daily injections —preferably 3, in order to maintain blood levels of the Yohimbine HCL throughout the day.

    On another note, this stuff should be injected directly into your bodyfat when used for spot reduction, not I.M. or even sub-q. It can be injected sub-q if one isn’t trying to spot reduce, but according to those who have personal experience with the drug, it tends to burn a bit when administered in this fashion. Whether this is due to the way in which some particular products are manufactured, or a direct result of the drugs themselves, I do not know, but it is worth mentioning.

    If there is one downside to Helios, it is the inability to control the ratio of Clen to Yohimbine. Most people will be able to handle 10-12 mg of Yohimbine HCL daily right up front when administered in 3 equally divided doses, but much fewer people can handle 80-100 mcg Clen under the same circumstances, especially when the product is properly dosed. Therefore, one would have to build a considerable tolerance to Clenbuterol before reaching an optimal dose or Yohimbine HCL. For those people who are using around 80 mcg daily, the ratio is just about perfect, supplying 10 mg Yohimbine for every 80 mcg of Clen.

    Regardless of whether your goal is whole-body fat loss and/or spot reduction, results will manifest quickly. However, it is important to remember that as a Clen product, receptor down-regulation will occur rapidly—in about 2 weeks, requiring the user to do one of three things: 1) Follow a 2 week ON/ 2 week OFF protocol 2) Continue to increase the dose in order to overcome the growing desensitization 3) Use ketotifin in combination with Helios. This will prevent receptor down-regulation, thereby allowing the user to continue using the drug uninterrupted and without the need for excessive dosages. Although Ketotifin may allow for extended use, I generally don’t recommend Helios or any Clen product be run for longer than about 4 weeks continuously, due to the increased potential for cardiac damage.

    In recent years there seems have developed a lax attitude among many in the drug using community, in which all drugs are viewed as inherently safe, even when used at higher dosages and/or for lengthy periods of time. These individuals often try to justify their irresponsible use by citing deceiving statistics, thereby minimizing the potential for harm associated with these drugs. Although Clen is generally well tolerated when used at appropriate doses and for reasonable lengths of time, it is unwise to push the limits with this drug, especially one as potent and hard hitting as Helios. As always, stay safe and continue to enjoy the benefits of today’s BB’ing pharmacology.

    Go Clemson.

  13. Sounds very interesting and I want to try it now haha what do you reckon the solution is? Could I just make my own? And who can't handle 80mcg of clen?!?! Haha

  14. Quote Originally Posted by Juicedeez utz View Post
    Sounds very interesting and I want to try it now haha what do you reckon the solution is? Could I just make my own? And who can't handle 80mcg of clen?!?! Haha
    That's what I was thinking, I can find injectable clen for cheap, but injectable yohimbine hcl seems to be hard to find, I'm going to have to actually spend time searching.
    Until then I'll be using this old bottle of SNS yohimbine I got.
    I can feel 2.5mg orally pretty good, so it really has me curious how getting 100% feels

    Go Clemson.

  15. Quote Originally Posted by brofessorx View Post
    That's what I was thinking, I can find injectable clen for cheap, but injectable yohimbine hcl seems to be hard to find, I'm going to have to actually spend time searching.
    Until then I'll be using this old bottle of SNS yohimbine I got.
    I can feel 2.5mg orally pretty good, so it really has me curious how getting 100% feels
    Same, I feel I'm getting better results mixing them orally to be fair! I'll get on the look for some inj clen but I can't seem to get much vet grade stuff! I need a horse friend haha

  16. Quote Originally Posted by brofessorx View Post
    Title states it all, looking for personal experiences with this injectable combo pushed by the late great dan duchaine.

    I originally posted in the aas section but thought it'd be better here.

    A side note, eviscerate an clen rubbed on aren't the same thing, especially since they took the aminophylene out, which makes it mediocre imo.
    Eviscerate supernova has aminophylline in it.
    OLYMPUS LABS
    My posts outside of OL threads are my opinion, don't take them as offensive!
    [email protected]

  17. I have used this and absolutely love it. Fat melts off with this stuff and you dont get the typical clen sides.

  18. I actually have researched this a 2ml daily (80mcg clen +10.8 mg yohimbine)+ pharm clen (100mcg) and I was sweating non stop. I am very clen tolerant and dont really get bad sides but I literally had none from the IM clen. The yohimbine was actually worse as I am sensitive to it.
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