I'm not sure how you are applying this, or looking to apply this, and I've seen no studies that I can point to, but I wouldn't doubt some are out there.
In my experience I will say that I have many obese people in my family, and they got to a certain point and they just stop gaining weight. It seems as though there is a "set" point at which they stay if they are not trying to change anything. If this is entirely physiological I don't know - it could be argued that they eat a certain amount of food and that amount of food allows for a certain weight, etc. I'm sure it works both ways.
For myself, as I've been losing weight over the past year I've noticed that if I give myself longer to lose weight it appears as if my body tries to establish set points along the way (I am willing to take 2-3 years to actually get in the shape I want, which requires losing 100 pounds and putting on over 30 pounds of muscle). What seems to happen is that I lose about 5 pounds, then it stops for a while and then I suddenly lose about 5 pounds more, then it stops. The 5 pounds comes over the course of a day or 2 each time, and once it is gone, I seem to be able to gain back the 5 pounds if I increase my eating, but it stops again and then the 5 pounds is easier to lose. So, what I've been doing is letting myself lose the 5 pounds, stay there for a while, then refeed and gain 2-5 pounds (which takes longer than you think) and then go back to eating less and I lose 5 pounds fast and then suddenly another 5 pounds will come off. It is kind of weird, but it may be more psychological than physical. I am sure that if I continued to eat above maintenance for an extended period of time I would gain most of the weight back - but when I was at my heaviest I didn't watch anything I ate and was at the same point for years and years.
I don't know if I'm conveying my thoughts well - but in a nutshell I think our body (and our brains) tries to establish set points but calories in/calories out will always create changes.