I can't get drunk??

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  1. I can't get drunk??


    Well, actually, I can get drunk.....fairly easily...

    but one of my friends, they cannot get drunk to save thier lives...

    they, no ****, had like 8 shots, 2 beers, 1 wine cooler, and a mixed drink all in the span of about 40 minutes or so... and was only slightly beginning to get a buzz, and the thing is...they're not really a consistent drinker (meaning, only drinking every once in a while)

    if I had that much, I would probly pass out, and need to have my stomach pumped.

     

    So....the question I have is:

    How can this person have such a high tolerance for alcohol, while at the same time being a "novice" drinker?

    does it have something to do with how their liver processes the alcohol??

     

    YJ, I would especially like your input on this since the human liver is one of your specialties.

     

    Thanks ahead of time,

    LG.  
    Read This Book!!: Anabolic Steroids and the Athlete by William N. Taylor M.D.


  2. theres a process where the liver sorta gelss so it takes more alcohol too get drunk(least thats the explanation i heard from a drunk biochem student..lol)
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  3. Is the guy fat? I think that can make a difference. And some people can just handle more alcohol then others.

  4. Originally posted by Inzah Dude
    Is the guy fat? I think that can make a difference. And some people can just handle more alcohol then others.
    She is not fat ... I am just was curious as to how (in a technical way )she can drink so much more than I can and not get wasted

    Read: I wanna get her drunk so I can do her j/k

     

    LG.
    Read This Book!!: Anabolic Steroids and the Athlete by William N. Taylor M.D.

  5. you know what it is LG...its the one wine cooler that counterbalanced the rest of the real drinks (ha). seriously though, i dont think the liver has to do too much concerning how much one must drink to get crunk, only the idea of being able to handle an X amount of alcohol able to withstand. body mass will help take in more, so would how long the dude been drinking. you can definetely build up tolerance. SHoot, i dont know the real scientific answer....just shooting the breeze. Sage

  6. Were you with her afterwards or just for the time she was drinking? Cuz if she drank it all quick in 40 minutes then just started to feel buzzed, it liekly all started to sink in later on so as time went on she would get pissed as all the alcohol soaked in. See what I'm saying?

  7. Question Posted By: Roxane C-M on Tuesday, November 09, 1999



    Although I am a PhD psychologist, I also finished nursing school and went three years in med school(yeah, hind sight is always 20/20, you should hear my farther). I tend to look at things from a bio-medical perspective(and a little knowledge is a dangerous thing!) I evaluate/ diagnosis and recommend alternative sentencing in our court. Although I head a department, most of the people that work for me have a very staid line surrounding the dymanics of this disease. I was always tatught that a blood alcohol level above a certain level is a primary indicator of clinical tolerance for alcohol. ex. A BAl of .17 and showing no clear, articulated effects of the drug. OR.....having a BAL of .59(I have witnessed two folks), being conscious, somewhat lucid while keeping some control of muscles and no empting of the bladder. I was even more convinced of this BAL indicator after reading and digesting Dr. Schukitt's work. At times these level occur in young people without an articulated history(significant other)of "practiced drinking". Will you help me?

    Answer Posted By: SA, M.D. - HVMA on Sunday, November 14, 1999

    High BALs with little intoxication typically indicate tolerance which has been gained by regular heavy drinking. Nonetheless, Schuckitt's work does indicate some significant individual variation in folks who are not alcohol dependent. In some young people, self-report information is not all that reliable. Those are my thoughts in a nutshell.

  8. Metabolic tolerance
    A tolerance that results from a more rapid elimination of alcohol from the body is called metabolic tolerance. This type of tolerance is due to a specific group of liver enzymes that are activated after prolonged drinking. These enzymes increase the speed at which alcohol is broken down. As a result, this reduces the time during which alcohol is active in the body. Therefore, the time during which alcohol’s intoxicating effects are felt is shortened. A danger associated with this type of tolerance is an increased metabolism of some prescription medications, such as those used to prevent blood clotting and to treat diabetes. This increased
    metabolism of the medications reduces the duration of their effectiveness, and this can cause harmful physical effects for
    the drinker.

  9. Tolerance and the Predisposition to Alcoholism

    Studies have shown that tolerance can be influenced greatly by genetics. Research indicates that individuals who have
    alcoholic parents were less impaired by alcohol, as compared with individuals who have nonalcoholic parents. Therefore, tolerance and the predisposition to alcoholism have been shown to be genetically linked.

  10. She may not have a tollerance to high blood alcohol at all. Maybe the alcohol isn't reaching the blood. Perhaps the pyloric valve closes very quickly and no alcohol gets through fast enough to make her drunk. It possibly lets small amounts through at a time not allowing her to get drunk.

    Does her stomache seem to get full when she drinks alot, like everything stays in there for a while?
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  11. Originally posted by windwords7
    Metabolic tolerance
    A tolerance that results from a more rapid elimination of alcohol from the body is called metabolic tolerance. This type of tolerance is due to a specific group of liver enzymes that are activated after prolonged drinking. These enzymes increase the speed at which alcohol is broken down. As a result, this reduces the time during which alcohol is active in the body. Therefore, the time during which alcohol’s intoxicating effects are felt is shortened. A danger associated with this type of tolerance is an increased metabolism of some prescription medications, such as those used to prevent blood clotting and to treat diabetes. This increased
    metabolism of the medications reduces the duration of their effectiveness, and this can cause harmful physical effects for
    the drinker.
    This is exactly what I was thinking WW, and this makes sense, since she made like 6-7 trips to the bathroom to go urinate in the space of about 1.5 hours.

    Thanks WW.

     

    LG.
    Read This Book!!: Anabolic Steroids and the Athlete by William N. Taylor M.D.

  12. Originally posted by ex_banana-eater
    She may not have a tollerance to high blood alcohol at all. Maybe the alcohol isn't reaching the blood. Perhaps the pyloric valve closes very quickly and no alcohol gets through fast enough to make her drunk. It possibly lets small amounts through at a time not allowing her to get drunk.

    Does her stomache seem to get full when she drinks alot, like everything stays in there for a while?
    If your stomach does get real full when you drink lots, what does this mean?

  13. Pyloric valve shuts not allowing anything to leave your stomache since the alcohol takes a long time to digest.

  14. Originally posted by windwords7
    Tolerance and the Predisposition to Alcoholism

    Studies have shown that tolerance can be influenced greatly by genetics. Research indicates that individuals who have
    alcoholic parents were less impaired by alcohol, as compared with individuals who have nonalcoholic parents. Therefore, tolerance and the predisposition to alcoholism have been shown to be genetically linked.
    Bump this. That's what I think it is, unless she's a heavy drinker. I don't know the science behind it but according to my Dad (an alcoholic) alcoholics have a much higher tolerance to getting drunk especially when they start drinking. Does alcoholism run in your friend's family?

    I doubt it is not reaching the bloodstream. Alcohol has a very high propensity for getting into the bloodstream, even through the mucous membranes in the mouth when you first swallow it (esp. hard alcohol).

    Another possibility is a medication your friend is taking that blocks the neurological effects of alcohol... you should ask her what medications she is taking. This is relatively unlikely but possible IMO.

    David

  15. Well, as someone who can down an entire bottle of Jack Daniels and not really feel it, I would agree, it is genetics or the stomach. When I drink, I do hit the mens room 7-8 times, so perhaps I am one of the lucky ones. I dated a girl like that who could match me shot for shot, and niether of us would get really drunk..so it has to ne someting either genetic or metabolic. Now I can do this with most hard alcohol. Wine, on the other hand, will hit me hard after 4-5 glasses, so go figure.

    As far as getting her drunk to get laid..how pitiful can you be? If you need a girl to be ****ed up to have sex with you, then what does that say about you? Personally, I have a rule I live by, and that is that the first time I am with a girl, she must be sober. After that, I really don't care. That rule started because I had a roommate who hooked up with a drunk girl...she claimed rape the next day. Charges were eventually dropped, yet his life was a living hell for about 6 months. Just isn't worth it to me.

  16. Originally posted by wardog

    As far as getting her drunk to get laid..how pitiful can you be? If you need a girl to be ****ed up to have sex with you, then what does that say about you?
    Hey man I was just joking around when I said that, I could never do that to a girl.  I was raised with WAY higher moral values than that.

    I repeat: I was just joking

     

    LG.
    Read This Book!!: Anabolic Steroids and the Athlete by William N. Taylor M.D.

  17. Originally posted by shpongled


    ...unless she's a heavy drinker. ....Does alcoholism run in your friend's family?
    you should ask her what medications she is taking.
    She is not a heavy drinker: she drinks maybe 1-2x a month, alcoholism does not run in her family, and, no she is not taking any medications (except for topical benzyl peroxide for her occasional break-outs)

    LG.
    Read This Book!!: Anabolic Steroids and the Athlete by William N. Taylor M.D.

  18. Originally posted by Lifeguard
     
    no she is not taking any medications (except for topical benzyl peroxide for her occasional break-outs)

    LG.
    You have it baaddd for this girl. LOL! Only the guy playing the rold of the sensitive, caring, intouch with your feminine side, role would know this about a girl that he wasn't even dating!!! Let me guess you talk for hours on the phone?
    Last edited by windwords7; 02-13-2003 at 12:02 AM.

  19. Originally posted by windwords7


    You have it baaddd for this girl. LOL! Only the guy playing the rold of the sensitive, caring, intouch with your feminine side, role would no this about a girl that he wasn't even dating!!! Let me guess you talk for hours on the phone?
    LOL!!!

    Actually, we were together for a while.  That is how I know all these little "intimate" details about her .... we're still really good friends.

     

    LG.
    Read This Book!!: Anabolic Steroids and the Athlete by William N. Taylor M.D.

  20. Originally posted by Lifeguard


    Hey man I was just joking around when I said that, I could never do that to a girl.  I was raised with WAY higher moral values than that.

    I repeat: I was just joking

     

    LG.
    Good deal bro..just making sure..I know TOO many guys who DO think that way, and it really pisses me off. I apologize if I misunderstood you.
  21. I can't get drunk either!


    I'm in my mid 50's and have never been drunk, not even a bit tipsy or slightly inebriated...totally sober my whole life. I'm not really a drinker, but I've always wondered what being tipsy or drunk feels like. The other day I drank the most I've ever drank ever! I had six screwdrivers (doubles) within maybe a couple of hrs. or less. The last couple I drank just like orange juice, pretty quickly. However, I felt nothing at all. It's like I never drank anything! What the heck is going on? I could probably drink ten doubles and not feel anything! I think I'm immune to alcohol...darn it!

  22. Windwords is pretty much dead on. I know some people underproduce the Class 1 Alcohol dehydrogenase enzyme. And pretty much one beer can screw them up the whole night... but there is always a paradigm to consider, so you can be sure that some people OVERproduce the Class 1 Alcohol dehydrogenase enyzme and metabolize alcohol at a extremely rapid pace.

    Looks like everclear for her.

    Adams
    The Historic PES Legend

  23. Careful -- She could in fact be VERY drunk, life-threateningly drunk, without showing it. Alcohol doesn't affect everyone in the same manner.

    This can also be a problem for alcoholics or those with a history of alcoholism in the family. Part of the nueroadaptation of dependence is the brain's compensating for things you'd normally identify as the outward signs of intoxication.

  24. Seriously, I'd kill to not have such high tolerance... I can easly drink about 18 beers in less than 2 hours and not be feeling bad at all, still have control over everything, etc.

    Is it sweet to be able to hold your lichor? Yeah, kinda. The problem is, if I want to feel a little buzzed I have to spend a sh!t load of money.

    I'd go back to being buzzed on the 6th beer anyday.
  25. Unbreakable
    David Dunn's Avatar

    This has got to be the oldest bumped thread I have even seen. Congratulations meee!

    DAdams91982 is correct.

    In alcoholics or alcoholism it is a later stage of progressive tolerance. Unfortunately very often as you get further into the later stages of alcoholism the liver begins to under produce. IOW the same amount or less alcohol will produce increased intoxication. It's a very good sign that the end of your drinking days may be coming to a close...if you are lucky.
    Life is a terminal condition.

  26. I wouldn't be so quick to congratulate me, B5150. I just want to get tipsy at least once in my life, just to know what it feels like. I have a very high curiosity, so this is killing me. I also can't seem to be hypnotized either, so I'm not a happy camper!
  27. Unbreakable
    David Dunn's Avatar

    Some of us draw the short straw I guess.

    Seriously, have you ever had a need for any liver testing. It would be interesting to see a liver profile of someone with your tolerance to alcohol.
    Life is a terminal condition.

  28. I have an abnormal tolerance to alcohol in general. I had to have a physical for a new insurance company and had a basic blood test. Apparently they found something and went further with a liver enzyme test. They ended up doing the test three different times. They thought I had hepatitis (I was not jaundiced), a bacterial infection, or something else. Long story short they found nothing wrong in general but really high enzymes. Maybe that's linked to the drinking, I dunno. But I'm also not one of the rapid pissers, that takes me a while as well.

  29. A few weeks ago, I decided to try drinking 10 shots of tequila (Jose Cuervo). This stuff is 40% alcohol and it's the worst tasting stuff ever, but nevertheless, I drank 10 shots in about an hr. and a half. I took a shot about every 10 minutes or so. I was somewhat unsteady on my feet, but didn't fall over. That's about it. Everything else was pretty normal. Talked normal, could think normal, I even surfed the net and posted messages with no problem at all. Didn't throw up or even felt like it. No hangover next morning, just a wee bit of a sensitive stomach so I ate breakfast real slow, but I never felt like throwing up. No headache, nadda.

    So I think I've officially quit trying to get drunk. I'm done.

  30. Quote Originally Posted by Lifeguard View Post
    Well, actually, I can get drunk.....fairly easily...

    but one of my friends, they cannot get drunk to save thier lives...

    they, no ****, had like 8 shots, 2 beers, 1 wine cooler, and a mixed drink all in the span of about 40 minutes or so... and was only slightly beginning to get a buzz, and the thing is...they're not really a consistent drinker (meaning, only drinking every once in a while)

    if I had that much, I would probly pass out, and need to have my stomach pumped.

     

    So....the question I have is:

    How can this person have such a high tolerance for alcohol, while at the same time being a "novice" drinker?

    does it have something to do with how their liver processes the alcohol??

     

    YJ, I would especially like your input on this since the human liver is one of your specialties.

     

    Thanks ahead of time,

    LG.  

    Dude i used to drink all the time and then lost 46 pounds of what im pretty sure was the beer weight and now i cant hold a 6 pack...
  

  
 

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