- 03-01-2008, 06:10 PM
- 03-01-2008, 06:27 PM
- 03-01-2008, 08:48 PM
03-02-2008, 03:54 AM
formestane will definitely work with penetrate... if I'm not mistaken, i believe that about 12 grams will fit in the 8oz bottle...
03-12-2008, 08:02 PM
03-12-2008, 09:06 PM
It will work with dmso but with probably less absorption and more irritation and dryness which will decrease absorption even more over time.
Most good carriers contain emolients, solvents and chemical penetration enhancers (CPE). They work on multiple levels to enhance penetration and absorption.
Give a man a fish, feed him for a day. Teach a man to fish, feed him for life. Lao Tse 6th century BC
03-12-2008, 10:56 PM
03-12-2008, 10:58 PM
Less absorption with DMSO?
Granted, I've never worked with it, but I've been under the impression for decades that DMSO was the *gold standard* for transdermal agents.
The fact that it's a solvent and a penetratOR would seem to argue in its favor over blends apparently don't penetrate the skin themselves; but then, I'm trying to figure this stuff out. Since DMSO seems to be almost unused as a transdermal carrier in these parts, I figure it's either not all that, or there are compelling reasons (which I guess I can't see) why it's not used for what it seems best at. Can you straighten me out on this?
03-12-2008, 11:08 PM
03-14-2008, 02:07 AM
I recently asked a question similar to this.
I got penetrate AND DMSO and mixed them together. Yes, DMSO will work as a TD by itself, but not that well, and not for long.
It will start to irritate and dry out your skin causing less to be absorbed. The penetrate will hellp prevent that to some extent
The penetrate and the DMSO work via different "pathways" so by combining both you have better absorption overall
Look at Johnny's log he knows all about it, you'll learn a lot just by reading that
03-15-2008, 02:23 AM
03-15-2008, 07:55 PM