2. Depends on your carrier. Using something like Penetrate, no just add powder to bottle in hot water bath, shake and your done. To something like phlojel it may benefit you to triturate powder with a solvent or penetration enhancer such as DMSO or D-limonene
3. Mixing= mortar & pestle. Bottling= whatever the carrier comes in. For Phlojel, I use 60ml syringes. It is a gel so the syringe is perfect.