This question was asked in a separate thread around a product that was recently released. Thought this was an appropriate forum to attempt to answer that question and possibly provide space for some discussion on the topic.
So, does "pump" contribute to muscle growth or performance?
More complex answer: Increased intracellular hydration causing the muscle fibers to swell, also known as"the pump", may possibly contribute towards hypertrophy via cell swelling -> regulation of cell function -> increased protein synthesis & decreased protein breakdown = protein accretion. Or in other words, cell swelling (pump) may promote hypertrophy by impacting net protein balance (synthesis & degradation) in muscle fibers (especially fast twitch due to more AQP4).
There are some other theories to such as hyperhydration having an effect on amino acid transport systems, increased pressure on the cell membrane via swelling initiates an intracellular signaling response via volume osmosensors within muscle fibers which initiate activation of anabolic protein-kinase transduction pathways, or that cellular swelling enhances hypertrophic adaptations via increased satellite cell activity.
Overall, the exact underlying mechanisms as to "how" achieving a pump in the gym benefits us has yet to be fully understand, anecdotally along with some scientific reasoning (hypotheses) it is a safe bet to assume it does contribute to gains.
So, does "pump" contribute to muscle growth or performance?
More complex answer: Increased intracellular hydration causing the muscle fibers to swell, also known as"the pump", may possibly contribute towards hypertrophy via cell swelling -> regulation of cell function -> increased protein synthesis & decreased protein breakdown = protein accretion. Or in other words, cell swelling (pump) may promote hypertrophy by impacting net protein balance (synthesis & degradation) in muscle fibers (especially fast twitch due to more AQP4).
There are some other theories to such as hyperhydration having an effect on amino acid transport systems, increased pressure on the cell membrane via swelling initiates an intracellular signaling response via volume osmosensors within muscle fibers which initiate activation of anabolic protein-kinase transduction pathways, or that cellular swelling enhances hypertrophic adaptations via increased satellite cell activity.
Overall, the exact underlying mechanisms as to "how" achieving a pump in the gym benefits us has yet to be fully understand, anecdotally along with some scientific reasoning (hypotheses) it is a safe bet to assume it does contribute to gains.