Honestly, It will probably be OK. Oxycodone like all opiates work on various opiate receptors in the brain and thereby reduce your pain.... Things to avoid while on Oxy:
1. Muscle relaxers like Soma and Flexiril. This can lead to
respiratory depress which can lead to DEATH

2. Fatty meals can also increase the absorption of oxycodone
significantly.
Your typical supplement will not cause any serious potentiation of oxycodone.
Common drugs that should not be mixed with Oxy:
Cimetidine
Prozac or any other SSRI's
Lasix
HCTZ
Hope this helps