So ive been looking at this product a lot and i really like what i hear. I really like that product promises a increase in ability to recover from training, but how? The description talks about how it utilizes cAMP synergism. Cyclic amp is a secondary messenger used in transduction of receptor chemicals such as Epinephrine to induce a cellular response such as breaking down glycogen using glycogen phosphoralase. cAMP is only a secondary messenger used with transmembrane G-proteins to start a phosphoralation cascade and a cellular response. How does this product actually work? By what means does it accomplish what it says it does? Does anyone have information or results from taking it?
The agent you may want to research in DRIVE for its performance enhancing effects is the Icariian. Here's a starter for ya:
The testosterone mimetic properties of icariin.
Zhang ZB, Yang QT.
Department of Urology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.
[email protected]
AIM: To evaluate the testosterone mimetic properties of icariin. METHODS: Forty-eight healthy male Sprague-Dawley rats at the age of 15 months were randomly divided into four groups with 12 rats each: the control group (C), the model group (M), the icariin group (ICA) and the testosterone group (T). The reproductive system was damaged by cyclophosphamide (intraperitoneal injection, 20 mg/kg x day) for 5 consecutive days for groups M, ICA and T, at the sixth day, ICA (gastric gavage, 200 mg/kg x day) for the ICA group and sterandryl (subcutaneous injection, 5 mg/rat . day) for the T group for 7 consecutive days, respectively. The levels of serum testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH), serum bone Gla-protein (BGP) and tartrate-resistant acid phosphatase activity in serum (StrACP) were determined. The histological changes of the testis and the penis were observed by microscope with hematoxylin-eosin (HE) staining and terminal deoxynucleotidyl transferase biotin-dUTP-X nick end labeling (TUNEL), respectively. RESULTS: (1) Icariin improved the condition of reproductive organs and
increased the circulating levels of testosterone. (2)
Icariin treatment also improved the steady-state serum BGP and might have promoted bone formation. At the same time, it decreased the serum levels of StrACP and might have reduced the bone resorption. (3) Icarrin suppressed the extent of apoptosis of penile cavernosal smooth muscle cells. CONCLUSION:
Icariin has testosterone mimetic properties and has therapeutic potential in the management of hypoandrogenism.
PMID: 16751992 [PubMed - indexed for MEDLINE]