Pyridoxal 5 Phosphate

  1. Pyridoxal 5 Phosphate


    Anyone happen to know any sites/stores/products from which this form of B6 can be bought?


  2. Quote Originally Posted by MrBrightside View Post
    Anyone happen to know any sites/stores/products from which this form of B6 can be bought?
    Vitamin Shoppe has it.

  3. Would you follow the dosing recommendations, or up them? It says only 1 tablet/ day (50mg).
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  4. Quote Originally Posted by MrBrightside View Post
    Would you follow the dosing recommendations, or up them? It says only 1 tablet/ day (50mg).
    For what use? Most use it along with hormones which can increase prolactin since P5P reduces prolactin.

  5. Metabolism of fat, and aiding with protein intake.

  6. I have a bottle of 50mg pills that says to take 2-3 daily so I suppose it depends on the manufacture. However it's not toxic like straight B6 can be in high doses so I'd think you can take as much as you need for results.

  7. 100-200 mg is the dosage I am typically seeing.
  8. Never enough
    EasyEJL's Avatar

    yeah, on cycle i'd say a min of 200 a day, off cycle I think 100 a day is probably enopugh, well spread thru the day is best.
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  9. Thanks everyone, think I'm going to start at 100-150 mg/day =]

  10. i bought mine at Nutraplanet....NOW brand.

  11. Quote Originally Posted by pistonpump View Post
    i bought mine at Nutraplanet....NOW brand.
    Same here.

  12. L- Dopa is also known to have prolactin halting effects. However I believe that the many other effects of L-dopa may not be worth using it for lowering prolactin. Especially after finding the following extract:

    Prolactin inhibition test with L-dopa: decrease and restoration of plasma prolactin levels in the rat by a peripheral process
    AA van der Gugten, PC Sahuleka, GH van Galen, and HG Kwa


    L-DOPA, within 30 min after administration, induced a highly significant decrease of plasma prolactin levels (phase 1) in a number of groups of rats, differing in age and/or endocrine status, apparently by direct inhibition of prolactin release from the pituitary. Three hours after administration of L-DOPA these low plasma prolactin concentrations in treated animals had increased (phase 2) and did not differ significantly from levels in control animals, indicating that the effect of L-DOPA on plasma prolactin levels is only of short duration. During this process some interesting phenomena were observed, especially in the animals treated with oestrone. The elimination rate of prolactin from plasma was very high (t 1/2 = 2.8 min), as indicated by decreasing concentrations of the hormone during phase 1. Pituitary prolactin content did not change during phase 1, suggesting that prolactin synthesis was also stopped. Notwithstanding the high elimination rate, plasma prolactin regained initial concentrations in phase 2, suggesting release of a substantial part of the pituitary prolactin content. The latter,however, remained constant during the whole experiment (i.e. before L-DOPA administration and during phase 1 as well as phase 2). The results suggested another working mechanism of L-DOPA in decreasing plasma prolactin levels, namely by stimulating the uptake of this hormone in the periphery. After the effect of L-DOPA had ceased, most of the prolactin from the periphery returned into the bloodstream, causing a rapid restoration of plasma prolactin levels without substantial release from the pituitary. The nature of the processes responsible for the peripheral uptake of prolactin is discussed.
  

  
 

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