powerfull vs Bulk 1-carboxy-2-amino-3-pyrobenzo

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    Quote Originally Posted by USPLabs View Post
    Maybe because doctors need to study disease or surgery. I'm sure they have time to read the recent issue of MD or FLEX. Such a whack arguement.

    You should order steamed vegetables and walk before buying a weight loss supplement...makes perfect unsarcastic sense.

    But You think PA knows his chemicals because you do not know any better nor should you. I'm would not expect an accountant to understand organic bio chemistry. In the eyes of the consumer, PA is the "Sh*t" becuase he designed a few steroids and made Costas live.

    When I talk Doctorates degree in India, I'm speaking in Chemistry.

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    Let's try to walk on the lighter side in this thread. It is currently overflowing with a lot of animosity and aggression. Not a very conducive environment for gaining great insights.
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    Quote Originally Posted by strategicmove View Post
    Let's try to walk on the lighter side in this thread. It is currently overflowing with a lot of animosity and aggression. Not a very conducive environment for gaining great insights.


    You bring order to a lot of chaos on this forum, my friend. Appreciated. Have no fear..... this won't escalate at all as far as I am concerned. Others.... I can't speak for.
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    Quote Originally Posted by Lanbane;


    You bring order to a lot of chaos on this forum, my friend. Appreciated. Have no fear..... this won't escalate at all as far as I am concerned. Others.... I can't speak for.
    Thanks, Lanbane. I trust you would stay cool!
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    Quote Originally Posted by Lanbane View Post


    You bring order to a lot of chaos on this forum, my friend. Appreciated. Have no fear..... this won't escalate at all as far as I am concerned. Others.... I can't speak for.
    I made an oath not to tell anymore goat jokes, so I think we're safe
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    Quote Originally Posted by USPLabs View Post
    Maybe because doctors need to study disease or surgery. I'm sure they have time to read the recent issue of MD or FLEX. Such a whack arguement.

    You should order steamed vegetables and walk before buying a weight loss supplement...makes perfect unsarcastic sense.

    But You think PA knows his chemicals because you do not know any better nor should you. I'm would not expect an accountant to understand organic bio chemistry. In the eyes of the consumer, PA is the "Sh*t" becuase he designed a few steroids and made Costas live.

    When I talk Doctorates degree in India, I'm speaking in Chemistry.

    nothing i have ever seen you write, or written on behalf of your company, has demonstrated any technical competence in chemistry
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    Quote Originally Posted by Patrick Arnold View Post
    nothing i have ever seen you write, or written on behalf of your company, has demonstrated any technical competence in chemistry
    You also have to recognize that his consumers don't have any technical competence in chemistry either. What's the point in talking something up in terms which the person buying it wouldn't understand?
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    Quote Originally Posted by thesinner View Post
    You also have to recognize that his consumers don't have any technical competence in chemistry either. What's the point in talking something up in terms which the person buying it wouldn't understand?
    i wasn't just talking about the advertisements but even if you are talking about the advertisements how do you defend him saying that L-dopa does not cross the blood brain barrier? Its as though he did not understand how the stuff functions in the first place yet he is claiming to sell some technologically advanced form of it
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    I just meant it in a general sense. I forgot about that argument.
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    I still have never gotten "Throbbing, Rock-Hard Erections That Last" either btw
    This space for rent

    Phenadrol Log http://anabolicminds.com/forum/suppl...-hell-did.html - AMAZING fat loss results so far
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    Quote Originally Posted by EasyEJL View Post
    I still have never gotten "Throbbing, Rock-Hard Erections That Last" either btw
    is that in their ads? That would be kinda creep me out rather than interest me, but then again I'm not the average consumer.
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    Actually thats what it reads here

    http://store.anabolicminds.com/produ...powerfull.html

    New and Improved PowerFULL caps available at NutraPlanet!
    “Discover Best-Selling Supplement That’s Taking The Bodybuilding Underground By Storm…”

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    Throbbing, Rock-Hard Erections That Last **
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    What More Can You Ask For?
    This space for rent

    Phenadrol Log http://anabolicminds.com/forum/suppl...-hell-did.html - AMAZING fat loss results so far
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    Ewww, I hope they don't last if you look at Rosie O'Donnel
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    Quote Originally Posted by EasyEJL View Post
    I still have never gotten "Throbbing, Rock-Hard Erections That Last" either btw
    I did get that effect from the old powerfull.
    And that at only 2 caps twice a day.
    And it did give me better rest becasue I work graveyard and on that old pfull I could sleep a straight eight hours in the daytime.
    Have not tried the new formula yet.
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    Quote Originally Posted by Patrick Arnold View Post
    i wasn't just talking about the advertisements but even if you are talking about the advertisements how do you defend him saying that L-dopa does not cross the blood brain barrier? Its as though he did not understand how the stuff functions in the first place yet he is claiming to sell some technologically advanced form of it
    THe PHD's from India told him that....
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    Quote Originally Posted by JPM View Post
    THe PHD's from India told him that....
    indians are an incredible pain in the ass to do business with. i don't mean that as a racist comment. its a cultural comment

    not that this has anything to do with this thread
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    Quote Originally Posted by Patrick Arnold View Post
    nothing i have ever seen you write, or written on behalf of your company, has demonstrated any technical competence in chemistry
    Well they sent over the study that showed quercertin did not increase resveratrols bio-availability, but you claim it dose. You seem to avoid the direct questions and attack others.

    I'll ask once MORE time. Can I post our test on your Cissus product?

    Science based articles may sale to 1% of the consumer base.
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    Quote Originally Posted by Patrick Arnold View Post
    indians are an incredible pain in the ass to do business with. i don't mean that as a racist comment. its a cultural comment

    not that this has anything to do with this thread
    Maybe it's you not the indians. You display a bitter personality. Complaing about others will not increase your sales.
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    Quote Originally Posted by USPLabs View Post
    Well they sent over the study that showed quercertin did not increase resveratrols bio-availability, but you claim it dose. You seem to avoid the direct questions and attack others.

    I'll ask once MORE time. Can I post our test on your Cissus product?

    Science based articles may sale to 1% of the consumer base.
    Are you referring to Giant's Cissus?
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    Quote Originally Posted by Patrick Arnold View Post
    indians are an incredible pain in the ass to do business with. i don't mean that as a racist comment. its a cultural comment

    not that this has anything to do with this thread
    my mother was an indian, watch what you say or you'll have a lawsuit on your hands

    i think it's you who's the pain in the rectum
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    Quote Originally Posted by Patrick Arnold View Post
    indians are an incredible pain in the ass to do business with. i don't mean that as a racist comment. its a cultural comment

    not that this has anything to do with this thread
    You should said that **** on costas. Can I quote you in my next write up..serious question.
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    Quote Originally Posted by Patrick Arnold View Post
    i wasn't just talking about the advertisements but even if you are talking about the advertisements how do you defend him saying that L-dopa does not cross the blood brain barrier? Its as though he did not understand how the stuff functions in the first place yet he is claiming to sell some technologically advanced form of it
    The problem is that other tissus like muscle absorb l-dopa (I'm not sure why or what its used for in other tissues) before sufficient amounts can reach the brain.
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    Quote Originally Posted by USPLabs View Post
    Well they sent over the study that showed quercertin did not increase resveratrols bio-availability, but you claim it dose. You seem to avoid the direct questions and attack others.
    there's been a few studies which have shown quercetin to inhibit the estrone sulfase enzyme. There's also been many studies showing that resveratrol is readily suflonated by this enzyme. I would imagine this is what PA is going off of.

    There's also been thought that the resveratrol metabolites might still be active to some degree.

    Another key word to note is "showed". You can "show" but that doesn't necessarily "prove".

    I'm not trying to take sides. USPLabs and ErgoPharm are both great companies and I enjoy their products. This thread is starting to turn into a
    "Your product sucks."
    "Oh yeah, well your product sucks worse." type of thread.

    I mean, I don't really understand what (if anything) you guys are trying to prove at this point, but it just makes both your companies look bad.
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    Quote Originally Posted by USPLabs View Post
    Well they sent over the study that showed quercertin did not increase resveratrols bio-availability, but you claim it dose. You seem to avoid the direct questions and attack others.

    I'll ask once MORE time. Can I post our test on your Cissus product?

    Science based articles may sale to 1% of the consumer base.
    what study are you talking about with quercetin

    you may not post any test on cissus. i answered this pages ago. you may forward the results to us privately for us to review, that is if you have anything at all
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    Quote Originally Posted by USPLabs View Post
    Maybe it's you not the indians. You display a bitter personality. Complaing about others will not increase your sales.
    i don't care about my sales

    i care about the truth
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    Quote Originally Posted by USPLabs View Post
    You should said that **** on costas. Can I quote you in my next write up..serious question.
    no.

    serious answer
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    Quote Originally Posted by USPLabs View Post
    The problem is that other tissus like muscle absorb l-dopa (I'm not sure why or what its used for in other tissues) before sufficient amounts can reach the brain.
    muscles "absorb" L-dopa

    are you for real?

    you idiot, its called peripheral decarboxylation
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    Quote Originally Posted by Patrick Arnold View Post
    what study are you talking about with quercetin

    you may not post any test on cissus. i answered this pages ago. you may forward the results to us privately for us to review, that is if you have anything at all
    Can someone (hopefully you PA), explain what is going on here with cissus.




    please, PM me if need be anyways.
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    Quote Originally Posted by thesinner View Post
    there's been a few studies which have shown quercetin to inhibit the estrone sulfase enzyme. There's also been many studies showing that resveratrol is readily suflonated by this enzyme. I would imagine this is what PA is going off of.
    going more of this and other studies.

    oh, and stop being so sensitive. let us fight


    Xenobiotica. 2000 Sep;30(9):857-66.Links
    Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids.De Santi C, Pietrabissa A, Spisni R, Mosca F, Pacifici GM.
    Department of Neurosciences, Medical School, Pisa, Italy.

    1. Resveratrol, a polyphenolic compound present in grape and wine, has beneficial effects against cancer and protective effects on the cardiovascular system. Resveratrol is sulphated, and the hepatic and duodenal sulphation might limit the bioavailability of this compound. The aim of this study was to see whether natural flavonoids present in wine, fruits and vegetables inhibit the sulphation of resveratrol in the human liver and duodenum. 2. In the liver, IC50 for the inhibition of resveratrol sulphation was 12+/-2 pM (quercetin), 1.0+/-0.04 microM (fisetin), 1.4+/-0.1 microM (myricetin), 2.2+/-0.1 microM (kaempferol) and 2.8+/-0.2 microM (apigenin). Similarly, in the duodenum, IC50 was 15+/-2 pM (quercetin), 1.3+/-0.1 microM (apigenin), 1.3+/-0.5 microM (fisetin), 2.3+/-0.1 microM (kaempferol) and 2.5+/-0.3 microM (myricetin). 3. The type of inhibition of quercetin on resveratrol sulphation was studied in three liver samples and was determined to be non-competitive and mixed in nature. Km (mean+/-SD; microM) was 0.23+/-0.07 (control), 0.40+/-0.08 (5 pM quercetin) and 0.56+/-0.09 (10 pM quercetin). Vmax (mean+/-SD; pmol min(-1) x mg(-1)) was 99+/-11 (control), 73+/-15 (5 pM quercetin) and 57 +/- 10 (10 pM quercetin). Kj and Kies estimates (mean+/-SD) were 3.7+/-1.8 pM and 12.1+/-1.7 pM respectively (p = 0.010). 4. Chrysin was a substrate for the sulphotransferase(s) and an assay was developed for measuring the chrysin sulphation rate in human liver. The enzyme followed Michaelis-Menten kinetics and Km and Vmax (mean+/-SD) measured in four livers were 0.29+/-0.07 microM and 43.1+/-1.9 pmol x min(-1) x mg(-1) respectively. 5. Catechin was neither an inhibitor of resveratrol sulphation nor a substrate of sulphotransferase. 6. These results are consistent with the view that many, but not all, flavonoids inhibit the hepatic and duodenal sulphation of resveratrol, and such inhibition might improve the bioavailability of this compound.

    PMID: 11055264 [PubMed - indexed for MEDLINE]
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    Quote Originally Posted by johnyq View Post
    Can someone (hopefully you PA), explain what is going on here with cissus.




    please, PM me if need be anyways.

    i have no clue what he is talking about. i told him that if he has anything then he should reveal the information to me privately and he has not.
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    Quote Originally Posted by Patrick Arnold View Post
    oh, and stop being so sensitive. let us fight
    lol, I'll try.
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    Quote Originally Posted by Patrick Arnold View Post
    muscles "absorb" L-dopa

    are you for real?

    you idiot, its called peripheral decarboxylation
    ****ing idiots.. need to get their heads out of their ass! :-p
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    Quote Originally Posted by itsrawb View Post
    ****ing idiots.. need to get their heads out of their ass! :-p
    dude, it's all your fault, u started this thread
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    Quote Originally Posted by b unit View Post
    dude, it's all your fault, u started this thread
    no ****. ****ing me!


    hah.. BURGER wTF:burg:
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    Quote Originally Posted by Patrick Arnold View Post
    i don't care about my sales

    i care about the truth
    dude you can't handle the truth, you're not tom cruise and this is not A Few Good Men
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    Quote Originally Posted by b unit View Post
    dude you can't handle the truth, you're not tom cruise and this is not A Few Good Men
    YOURE NOT ****ING TOM CRUISE... YOURE ****ING PATRICK ARNOLD ! HAVE A BURGER :burg:
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    Funny thing that all USP has done is evade questions, change his answers daily and attack PA. his statements on L-Dopa were moronic at best.

    PS I use bulk powerfull and love it, although it does make me get up at nights several times.
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    Quote Originally Posted by thesinner View Post
    I made an oath not to tell anymore goat jokes, so I think we're safe
    now the joke is about not telling the G word jokes hahaha yup thats the new thing here. the anti g word punches.
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    Quote Originally Posted by johnyq View Post
    Can someone (hopefully you PA), explain what is going on here with cissus.




    please, PM me if need be anyways.
    its probably not really 50% extract...
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    I'm wondering...

    If L-Dopa stimulates dopamine (sometimes dubbed as PIH, or prolactin inhibiting hormone), if it is taken before bed in conjunction with GHB, which is shown to inhibit dopamine pathways and increases prolactin secretion... Will L-Dopa stimulate enough dopamine to stop the prolactin from negating the HGH benefits from GHB?
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