Fish Oil Dosage
- 03-04-2007, 05:10 PM
- 03-04-2007, 09:15 PM
-
- 03-04-2007, 09:34 PM
That's a bit excessive.
Keep in mind that DHA levels should always be kept at lower levels than EPA.
While DHA displays neuroprotective properties.... when administered in excess, can actually display neurodegenerative properties.
AA and DHA are the most vulnerable targets for free radical-catalyzed lipid peroxidation. Docosanoids/neuroprostanes, are oxidation products of DHA. The compounds 4-hydroxy-2-hexenal/neuroketals, remain esterified to phospholipids, significantly inhibit proteasome, and are highly cytotoxic. This oxidative damage can lead to docosanoid-induced neurodegeneration, and is associated with neurodegenerative disease.
Fatty Acid Oxidation in the Pathogenesis of Alzheimer's Disease -- Montine and Morrow 166 (5): 1283 -- American Journal of Pathology
Formation of Highly Reactive gamma -Ketoaldehydes (Neuroketals) as Products of the Neuroprostane Pathway -- Bernoud-Hubac et al. 276 (33): 30964 -- Journal of Biological Chemistry
Fatty Acid Oxidation in the Pathogenesis of Alzheimer's Disease -- Montine and Morrow 166 (5): 1283 -- American Journal of Pathology - 03-04-2007, 09:57 PM
- 03-04-2007, 10:15 PM
"Keep in mind that DHA levels should always be kept at lower levels than EPA" **** - i thought it was the other way 'round! maybe ive reading too much at t-nation.
-
- 03-06-2007, 06:42 AM
- 03-06-2007, 07:23 AM
Similar Forum Threads
-
The End-All Fish Oil Dosage Thread
By purebred in forum SupplementsReplies: 125Last Post: 06-19-2012, 06:27 PM -
Fish Oil Dosage
By justiceTX in forum SupplementsReplies: 1Last Post: 10-29-2009, 11:50 PM -
flax/fish oil dosage question
By dlew308 in forum Nutrition / HealthReplies: 3Last Post: 01-26-2007, 10:24 PM -
Fish Oil dosage No2
By Deccadick in forum SupplementsReplies: 0Last Post: 11-08-2006, 06:19 PM -
Fish oil dosage
By Deccadick in forum SupplementsReplies: 3Last Post: 11-08-2006, 01:50 AM