Herbs that increase DHT

[Hyde12]

Im sick of everything that decreases DHT. Are there any herbal supplements on the market that will increase DHT?

 

[yeahright]

Just curious, why?

and

Have you tried searching pubmed?

 

[TripDog]

why do you want to increase DHT???I mean yea dht is totally responsable for the great feeling hormones/gear will give you.IMO it just seems dht can cause alot of problems too....kinda a catch 22 i guess.Although many studies contribute bph to estrogen..not dht...hmmm,as far as the hairloss issue...dude i love my hair,and even tho i am disposed to loosing it...i take finisteride,topical dutasteride,topical spiro,......to increase dht...hmmm,just take any AI,something like rebound xt will def increase dht....or anabolic extreme pct is a good go too! good luck bro,hope i helped in some way

 

[poison]

Hey, BRO! Far out, man, I'm on the same page, i mean, we like, totally connect on some deeper level. Check it out, man:

I'm sick of everything that increases muscle mass. I want herbals, man, hey, bro, no, not those herbals hehheh, regular herbals, like, but ones that will like make me small. I'm sick of being huge, man.

 

[naturalone76]

Poison you are so ignorant. DHT is the hormone that makes a MAN a MAN. Its responsible for healthy penis size, deeper voice, and sex drive. When you lower dht, you shrink your **** up, your voice sounds like a woman, and you have no desire to ****.
yeah poison, you're so right. dht is such a bad thing to have. NOT.

 

[funick972]

Sorry for my english but im french.DHT is the main androgenic hormone in the human body, necessery for estrogen/t ration, libido, semen production and prostate health.Lowering dht levels by inibiting alpha 5 reducatse enzyme activity leads to serious sexuals disorders and hormonal imbalance such as estrogen dominance , high prolactin levels and secondary hypogonadism.The best way to recover from these sides effects is to bring back estrogens levels in safe range (25-30 pg) while also reducing prolactin levels and increasing dht levels to normal range.

Calcium d glucarate in low doses is the best choice for reducing estrogens levels.Too much cdg=to low estrogens (same negative effects as high estrogens)

b6 vitamin is the safest way to reduce prolactin while cabergoline (dostinex) is more effective.Dostinex can have negative effects on serotonin levels and b6 in large dose is neurotoxic so be careful.

the best dht ehancer is creatine monohydrate ( im not kidding) , you can google it.Proviron also helps but its a synthetic dht.High fat diet also increase alpha 5 reductase

so take creatine monohydrate to increase dht levels

 

[MAxximal]

DHT - Is It All Bad?
by Patrick Arnold
Pat is responsible for launching several major product and innovation in the prohormone industry through LPJ Research and Ergopharm, including the first to release androstenedione, 1-AD, 6-OXO, 4-androstenediol, and 19-norandrostenediol. In addition, he is responsible for bringing innovative delivery systems to the prohormone market including HPB cyclodextrin, bioadhesive technology for sustained release, and sustained release sprays.



A considerable chunk of my work day is always spent answering people’s questions about prohormones and steroids. Of course, one of the biggest concerns people have is about estrogen and estrogen related side effects. Right behind that however are questions about DHT. It seems that people have the misconception that DHT is some evil androgen by product that serves no purpose in the body but to make our prostates blow up and our hair fall out.

The real situation is of course much more complex. DHT is one of those good guy / bad guy hormones that is sorely misunderstood. For many people, it is NOT something that you want to reduce or eliminate in the body. For some others though, keeping DHT levels under control is probably a prudent course of action. Knowing the facts about DHT will help you decide just which group you belong to.

Testosterone is a prohormone?

The main androgen secreted by the testes is of course testosterone. However, in most of the body, the androgenic signal is not carried through by testosterone. In these tissues, which include the brain (CNS), skin, genitals – practically everything but muscle – the active androgen is actually DHT. Testosterone in this case simply acts as a prohormone that is converted to the active androgen DHT by the action of the enzyme 5alpha reductase (5-AR).

5-AR is concentrated heavily in practically every androgen dependent area of the body except for skeletal muscle. This results in very little testosterone actually getting through to these parts of the body to bind to androgen receptors. Instead, it is quickly transformed into DHT, which then interacts with receptors.

This transformation serves a very important biological function in these tissues. You see, DHT is a much stronger androgen than testosterone – it binds about 3-5 times more strongly to the androgen receptor. If you took away 5-AR from these tissues and blocked the formation of DHT, then you would see some dramatic changes in physiology.

A good case in point is demonstrated in male pseudohermaphroditism due to congenital 5-AR deficiency. This is a relatively rare disorder, however it is actually quite common in the Dominican Republic. In this disorder, males are born with little or no 5-AR enzyme. They have ambiguous genitalia and are often raised as girls. When puberty occurs, their testosterone levels elevate normally although their DHT levels remain very low. Their musculature develops normally like that of other adults, however, they end up with little or no pubic / body hair and underdeveloped prostate and penis. Their libido and sexual function is often disrupted also.

Testosterone is the active androgen in muscle

Skeletal muscle is unique from other androgen dependent tissues in the body. It actually contains little or no 5-AR, so little or no DHT is actually formed in the muscle. In addition to this, any DHT that is formed, or that is already present in the blood and travels to the muscle, is quickly deactivated by an enzyme called 3alpha-hydroxysteroid reductase (3a-HSD).

So at least as far as muscle is concerned, testosterone is the primary active androgen. This is not to say that administering exogenous DHT is not without any anabolic effect. It actually does have some anabolic activity in the muscle, albeit significantly weaker than that of an equal amount of testosterone. This is due to its quick breakdown by 3a-HSD into the weak metabolite 5alpha-androstan-3a,17b-diol. If this enzyme were somehow blocked, it is likely that DHT would exhibit very potent anabolic effects on muscle.

It is important to understand that even though testosterone is the active androgen in muscle, and DHT exhibits relatively little direct anabolic effects on muscle in men, DHT is still very important for the full performance enhancement effects from testosterone. What I specifically mean here are the effects of DHT on the central nervous system, which lead to increased neurological efficiency (strength), and increased resistance to psychological and physical stress - not to mention optimal sexual function and libido.

I have heard several anecdotal reports of individuals who have stacked testosterone with proscar (a 5-AR inhibitor) and have noticed significantly reduced performance enhancement effects. What’s going on here? We know it couldn’t be due to the inhibition of the direct anabolic activity of testosterone on muscle anabolism. Most likely it is due to the reduction of androgenic effects in other parts of the body that contribute to the ergogenic effects, specifically the CNS, which is stimulated by androgens to increase neural output leading to greater strength and greater recoverability. Another possibility is a reduction in the production of androgen dependent liver growth factors (such as IGF-1), since DHT is an important androgen in the liver.

Anti – Estrogen effects of DHT

One important function of DHT in the body that does not get much discussion is its antagonism of estrogen. Some men that take Proscar learn this the hard way – by developing a case of gynecomastia. By reducing DHT’s protection against estrogen in the body, these men have fallen victim to its most dreaded ramification – bitch tits!

How does DHT protect against estrogen? There are at least three ways that this likely occurs. First of all, DHT directly inhibits estrogens activity on tissues. It either does this by acting as a competitive antagonist to the estrogen receptor or by decreasing estrogen-induced RNA transcription at a point subsequent to estrogen receptor binding.

Second of all, DHT and its metabolites have been shown to directly block the production of estrogens from androgens by inhibiting the activity of the aromatase enzyme. The studies done in breast tissue showed that DHT, androsterone, and 5alpha-androstandione are potent inhibitors of the formation of estrone from androstenedione. 5alpha-androstandione was shown to be the most potent, while androsterone was the least.

Lastly, DHT acts on the hypothalamus / pituitary to decrease the secretion of gonadotropins. By decreasing the secretion of gonadotropins you decrease the production of the raw materials for estrogen production – testosterone and androstenedione (DHT itself cannot aromatize into estrogens). This property of DHT comes into particular utility when it is administered exogenously, and this is to be discussed in further detail in the next section.

DHT, estrogen, and the prostate

When it comes to sex hormones, few things are as misunderstood by the general consumer as the relationship of the prostate to DHT. The inaccurate and overly simplistic attitude that DHT is responsible for prostate hypertrophy, and even prostate cancer predominates amongst most people.

The real situation is, of course, much more complex. One must understand that there are marked differences between healthy prostate growth (developmental growth), prostate growth due to BPH, and cancerous prostate growth.

The first period of prostate growth, deemed developmental growth, is connected to puberty and the testicular secretion of androgens. This takes the prostate from its prepubertal dormancy to the normal sized, healthy, and functional prostate gland of an adult. During the early and mid adult years the prostate stays at this stage, despite the constant high levels of androgens in the body. However, if androgens are blocked in the body then the adult prostate will shrink in size. This can occur by castration, or even by blockade of 5-AR (recall that DHT is the active androgen in the prostate).

Later in life, there is often a second stage of growth. This growth is deemed benign prostate hypertrophy (BPH) and this growth occurs in a wholly different hormonal environment than that of developmental growth. Evidence is mounting that the existence of a high estrogen / androgen ratio – a condition common in older men – is highly correlated to the development of BPH.

Experimental studies have shown the inability of androgens with saturated A rings (DHT related) to induce an initial condition of prostate hypertrophy. These compounds are non-aromatizable. Aromatizable androgens on the other hand, such as testosterone or androstenedione can induce hyperplasic modifications of the prostate of monkeys, but these effects are reversed by the addition of an aromatase inhibitor.

So apparently, estrogen is a causative factor in BPH or, probably more accurately, estrogen in the presence of a minimum, permissive amount of androgen.

None of this may come as news to many of you, but I bet that very few of you know that DHT can actually be used to treat BPH!! How can it do that? It basically does this by replacing the testosterone in the body, which then has the effect of reducing the amount of estrogen in the body. As I started to explain before, DHT is a strong androgen that will signal the pituitary to decrease the production of gonadotropins. The decrease in gonadotropins will then cause less testosterone to be produced which will in turn cause the estrogen levels to drop. The resulting change in the hormonal milieu (high DHT, low estrogen) then apparently results in a regression of BPH.

The clinical application of this theory is discussed in US patent 5,648,350 "Dihydrotestosterone for use in androgenotherapy". The following illustrates the results:

"In 27 subjects in which the plasma DHT level was controlled, so as to modulate the administered doses, said levels have been increased to 2.5 to 6 ng/ml. There resulted a decrease in gonadotrophy as well as in the plasma levels of testosterone which exceeded at least 1.5 ng/ml (from 0.5 to 1.4 according to the case); as to the estradiol plasma levels, these decreased by 50%.

Among this group of subjects, the volume of the prostate diminished significantly, as was evaluated by ultrasound and by PSA (Prostate Specific Antigen). The mean volume of the prostates was from 31.09.+-.16.31 grams before treatment and from 26.34.+-.12.72 grams after treatment, for a mean reduction of 15.4%, the treatment having a mean duration of 1.8 years with DHT (P=0.01)."

This kind of flies in the face of the traditional thinking concerning BPH now doesn’t it?

Conclusion

People have a natural tendency to classify things as either good or bad, with no gray areas. DHT (like estrogen) has recently been on everyone’s bad list, and is often considered to be a hormone that serves no function in the body except to cause harm. As you can see, this view is far from the truth. In my opinion, the widespread use of 5-AR inhibitors such as Proscar as a prophylactic agent for people that really don’t need it should be reconsidered. So give DHT a break.

 

[MAxximal]

Poison you are so ignorant. DHT is the hormone that makes a MAN a MAN. Its responsible for healthy penis size, deeper voice, and sex drive. When you lower dht, you shrink your **** up, your voice sounds like a woman, and you have no desire to ****.
yeah poison, you're so right. dht is such a bad thing to have. NOT.

This

 

[funick972]

wow maximal........great post

 

[ninjah9]

Great post by Maxximal.

 

[thebigt]

DHT - Is It All Bad?
by Patrick Arnold
Pat is responsible for launching several major product and innovation in the prohormone industry through LPJ Research and Ergopharm, including the first to release androstenedione, 1-AD, 6-OXO, 4-androstenediol, and 19-norandrostenediol. In addition, he is responsible for bringing innovative delivery systems to the prohormone market including HPB cyclodextrin, bioadhesive technology for sustained release, and sustained release sprays.



A considerable chunk of my work day is always spent answering people’s questions about prohormones and steroids. Of course, one of the biggest concerns people have is about estrogen and estrogen related side effects. Right behind that however are questions about DHT. It seems that people have the misconception that DHT is some evil androgen by product that serves no purpose in the body but to make our prostates blow up and our hair fall out.

The real situation is of course much more complex. DHT is one of those good guy / bad guy hormones that is sorely misunderstood. For many people, it is NOT something that you want to reduce or eliminate in the body. For some others though, keeping DHT levels under control is probably a prudent course of action. Knowing the facts about DHT will help you decide just which group you belong to.

Testosterone is a prohormone?

The main androgen secreted by the testes is of course testosterone. However, in most of the body, the androgenic signal is not carried through by testosterone. In these tissues, which include the brain (CNS), skin, genitals – practically everything but muscle – the active androgen is actually DHT. Testosterone in this case simply acts as a prohormone that is converted to the active androgen DHT by the action of the enzyme 5alpha reductase (5-AR).

5-AR is concentrated heavily in practically every androgen dependent area of the body except for skeletal muscle. This results in very little testosterone actually getting through to these parts of the body to bind to androgen receptors. Instead, it is quickly transformed into DHT, which then interacts with receptors.

This transformation serves a very important biological function in these tissues. You see, DHT is a much stronger androgen than testosterone – it binds about 3-5 times more strongly to the androgen receptor. If you took away 5-AR from these tissues and blocked the formation of DHT, then you would see some dramatic changes in physiology.

A good case in point is demonstrated in male pseudohermaphroditism due to congenital 5-AR deficiency. This is a relatively rare disorder, however it is actually quite common in the Dominican Republic. In this disorder, males are born with little or no 5-AR enzyme. They have ambiguous genitalia and are often raised as girls. When puberty occurs, their testosterone levels elevate normally although their DHT levels remain very low. Their musculature develops normally like that of other adults, however, they end up with little or no pubic / body hair and underdeveloped prostate and penis. Their libido and sexual function is often disrupted also.

Testosterone is the active androgen in muscle

Skeletal muscle is unique from other androgen dependent tissues in the body. It actually contains little or no 5-AR, so little or no DHT is actually formed in the muscle. In addition to this, any DHT that is formed, or that is already present in the blood and travels to the muscle, is quickly deactivated by an enzyme called 3alpha-hydroxysteroid reductase (3a-HSD).

So at least as far as muscle is concerned, testosterone is the primary active androgen. This is not to say that administering exogenous DHT is not without any anabolic effect. It actually does have some anabolic activity in the muscle, albeit significantly weaker than that of an equal amount of testosterone. This is due to its quick breakdown by 3a-HSD into the weak metabolite 5alpha-androstan-3a,17b-diol. If this enzyme were somehow blocked, it is likely that DHT would exhibit very potent anabolic effects on muscle.

It is important to understand that even though testosterone is the active androgen in muscle, and DHT exhibits relatively little direct anabolic effects on muscle in men, DHT is still very important for the full performance enhancement effects from testosterone. What I specifically mean here are the effects of DHT on the central nervous system, which lead to increased neurological efficiency (strength), and increased resistance to psychological and physical stress - not to mention optimal sexual function and libido.

I have heard several anecdotal reports of individuals who have stacked testosterone with proscar (a 5-AR inhibitor) and have noticed significantly reduced performance enhancement effects. What’s going on here? We know it couldn’t be due to the inhibition of the direct anabolic activity of testosterone on muscle anabolism. Most likely it is due to the reduction of androgenic effects in other parts of the body that contribute to the ergogenic effects, specifically the CNS, which is stimulated by androgens to increase neural output leading to greater strength and greater recoverability. Another possibility is a reduction in the production of androgen dependent liver growth factors (such as IGF-1), since DHT is an important androgen in the liver.

Anti – Estrogen effects of DHT

One important function of DHT in the body that does not get much discussion is its antagonism of estrogen. Some men that take Proscar learn this the hard way – by developing a case of gynecomastia. By reducing DHT’s protection against estrogen in the body, these men have fallen victim to its most dreaded ramification – bitch tits!

How does DHT protect against estrogen? There are at least three ways that this likely occurs. First of all, DHT directly inhibits estrogens activity on tissues. It either does this by acting as a competitive antagonist to the estrogen receptor or by decreasing estrogen-induced RNA transcription at a point subsequent to estrogen receptor binding.

Second of all, DHT and its metabolites have been shown to directly block the production of estrogens from androgens by inhibiting the activity of the aromatase enzyme. The studies done in breast tissue showed that DHT, androsterone, and 5alpha-androstandione are potent inhibitors of the formation of estrone from androstenedione. 5alpha-androstandione was shown to be the most potent, while androsterone was the least.

Lastly, DHT acts on the hypothalamus / pituitary to decrease the secretion of gonadotropins. By decreasing the secretion of gonadotropins you decrease the production of the raw materials for estrogen production – testosterone and androstenedione (DHT itself cannot aromatize into estrogens). This property of DHT comes into particular utility when it is administered exogenously, and this is to be discussed in further detail in the next section.

DHT, estrogen, and the prostate

When it comes to sex hormones, few things are as misunderstood by the general consumer as the relationship of the prostate to DHT. The inaccurate and overly simplistic attitude that DHT is responsible for prostate hypertrophy, and even prostate cancer predominates amongst most people.

The real situation is, of course, much more complex. One must understand that there are marked differences between healthy prostate growth (developmental growth), prostate growth due to BPH, and cancerous prostate growth.

The first period of prostate growth, deemed developmental growth, is connected to puberty and the testicular secretion of androgens. This takes the prostate from its prepubertal dormancy to the normal sized, healthy, and functional prostate gland of an adult. During the early and mid adult years the prostate stays at this stage, despite the constant high levels of androgens in the body. However, if androgens are blocked in the body then the adult prostate will shrink in size. This can occur by castration, or even by blockade of 5-AR (recall that DHT is the active androgen in the prostate).

Later in life, there is often a second stage of growth. This growth is deemed benign prostate hypertrophy (BPH) and this growth occurs in a wholly different hormonal environment than that of developmental growth. Evidence is mounting that the existence of a high estrogen / androgen ratio – a condition common in older men – is highly correlated to the development of BPH.

Experimental studies have shown the inability of androgens with saturated A rings (DHT related) to induce an initial condition of prostate hypertrophy. These compounds are non-aromatizable. Aromatizable androgens on the other hand, such as testosterone or androstenedione can induce hyperplasic modifications of the prostate of monkeys, but these effects are reversed by the addition of an aromatase inhibitor.

So apparently, estrogen is a causative factor in BPH or, probably more accurately, estrogen in the presence of a minimum, permissive amount of androgen.

None of this may come as news to many of you, but I bet that very few of you know that DHT can actually be used to treat BPH!! How can it do that? It basically does this by replacing the testosterone in the body, which then has the effect of reducing the amount of estrogen in the body. As I started to explain before, DHT is a strong androgen that will signal the pituitary to decrease the production of gonadotropins. The decrease in gonadotropins will then cause less testosterone to be produced which will in turn cause the estrogen levels to drop. The resulting change in the hormonal milieu (high DHT, low estrogen) then apparently results in a regression of BPH.

The clinical application of this theory is discussed in US patent 5,648,350 "Dihydrotestosterone for use in androgenotherapy". The following illustrates the results:

"In 27 subjects in which the plasma DHT level was controlled, so as to modulate the administered doses, said levels have been increased to 2.5 to 6 ng/ml. There resulted a decrease in gonadotrophy as well as in the plasma levels of testosterone which exceeded at least 1.5 ng/ml (from 0.5 to 1.4 according to the case); as to the estradiol plasma levels, these decreased by 50%.

Among this group of subjects, the volume of the prostate diminished significantly, as was evaluated by ultrasound and by PSA (Prostate Specific Antigen). The mean volume of the prostates was from 31.09.+-.16.31 grams before treatment and from 26.34.+-.12.72 grams after treatment, for a mean reduction of 15.4%, the treatment having a mean duration of 1.8 years with DHT (P=0.01)."

This kind of flies in the face of the traditional thinking concerning BPH now doesn’t it?

Conclusion

People have a natural tendency to classify things as either good or bad, with no gray areas. DHT (like estrogen) has recently been on everyone’s bad list, and is often considered to be a hormone that serves no function in the body except to cause harm. As you can see, this view is far from the truth. In my opinion, the widespread use of 5-AR inhibitors such as Proscar as a prophylactic agent for people that really don’t need it should be reconsidered. So give DHT a break.

this is exactly the reason i stopped use of erase while running androhard-the dht from androhard should cover any estrogen issues from my test cyp. i had been using erase for 3 months prior to the androhard, and will go back on it after the cycle is over.

 

[ninjah9]

Word to grey areas!

 

[BigBlackGuy]

this is exactly the reason i stopped use of erase while running androhard-the dht from androhard should cover any estrogen issues from my test cyp. i had been using erase for 3 months prior to the androhard, and will go back on it after the cycle is over.

Hell yah!

Erase is great, but would much rather be able to use it off cycle. Androhard is great for keeping estrogen at bay... DHT gets a bad rap a lot of the time, and it really shouldn't.

 

[francesco]

this is exactly the reason i stopped use of erase while running androhard-the dht from androhard should cover any estrogen issues from my test cyp. i had been using erase for 3 months prior to the androhard, and will go back on it after the cycle is over.

did androhard keep estrogen at bay with test cyp cycle? any other suggestions to enhance dht?

 

[MAxximal]

did androhard keep estrogen at bay with test cyp cycle? any other suggestions to enhance dht?

he`s use test cyp for TRT purposes

 

[andrew732]

Like I will always tell my listeners, DHT is just as important as Testosterone, the only difference is that with DHT you have to monitor your prostate and hair (if you are a pretty boy), but with testosterone you have to monitor your E2 levels. I love the idea of having optimal levels of both hormones, testosterone is for vitality and anabolism, DHT is for masculinity along vitality. People always think I am in my upper 20's because of my high DHT levels and all I know is I have a GREAT since of well being. Studies show that training at a high pace for an enduring period increases DHT, just watch your cortisol levels.

 

[francesco]

Sorry for my english but im french.DHT is the main androgenic hormone in the human body, necessery for estrogen/t ration, libido, semen production and prostate health.Lowering dht levels by inibiting alpha 5 reducatse enzyme activity leads to serious sexuals disorders and hormonal imbalance such as estrogen dominance , high prolactin levels and secondary hypogonadism.The best way to recover from these sides effects is to bring back estrogens levels in safe range (25-30 pg) while also reducing prolactin levels and increasing dht levels to normal range.

Calcium d glucarate in low doses is the best choice for reducing estrogens levels.Too much cdg=to low estrogens (same negative effects as high estrogens)

b6 vitamin is the safest way to reduce prolactin while cabergoline (dostinex) is more effective.Dostinex can have negative effects on serotonin levels and b6 in large dose is neurotoxic so be careful.

the best dht ehancer is creatine monohydrate ( im not kidding) , you can google it.Proviron also helps but its a synthetic dht.High fat diet also increase alpha 5 reductase

so take creatine monohydrate to increase dht levels[/QUOTE


my dht levels more then doubled, from 342ng(which is pretty low) to 842ng.. only supp I was on is creatine mono 5grams day and some alcar.. the BW are one year apart. Don't know if dht normally fluctuates much, but hope this helps!

 

[mr.cooper69]

Sorry for my english but im french.DHT is the main androgenic hormone in the human body, necessery for estrogen/t ration, libido, semen production and prostate health.Lowering dht levels by inibiting alpha 5 reducatse enzyme activity leads to serious sexuals disorders and hormonal imbalance such as estrogen dominance , high prolactin levels and secondary hypogonadism.The best way to recover from these sides effects is to bring back estrogens levels in safe range (25-30 pg) while also reducing prolactin levels and increasing dht levels to normal range.

Calcium d glucarate in low doses is the best choice for reducing estrogens levels.Too much cdg=to low estrogens (same negative effects as high estrogens)

b6 vitamin is the safest way to reduce prolactin while cabergoline (dostinex) is more effective.Dostinex can have negative effects on serotonin levels and b6 in large dose is neurotoxic so be careful.

the best dht ehancer is creatine monohydrate ( im not kidding) , you can google it.Proviron also helps but its a synthetic dht.High fat diet also increase alpha 5 reductase

so take creatine monohydrate to increase dht levels[/QUOTE


my dht levels more then doubled, from 342ng(which is pretty low) to 842ng.. only supp I was on is creatine mono 5grams day and some alcar.. the BW are one year apart. Don't know if dht normally fluctuates much, but hope this helps!

I actually came in here to say this lol! Mono elevates DHT BIG-TIME, BUT it was primarily during a loading phase, not maintenance.

 

[MattPorter]

Can I get some references on this? I believe I knew about this a few yrs back.,,,,but kinda brushed it off. Glycine + Methionine+ arginine = creatine = higher DHT levels. So crea mono might help reduce testosterone into DHT. I think the number something like 42% increase after loading.

Just another validation of why I recommend creatine POST CYCLE and not on cycle. I wonder if this increase is enough to claim creatine is anti estrogenic...

-Matt