Amino acids, despite their name, are actually a very weak base. Due to their weak basicity, they do not dissolve well in a neutral solvent (water). By lowering the pH of the solvent, we can enhance the dissolution of a weak base. This can be as easy as adding vitamin C to your BCAAs.
Would such changes in pH degrade the BCAA's?
thanks,
:smite: thesinner
Amino acids reside as zwitterions in both crystalline and aqueous forms. Zwitterions have the NH3+ and COO- groups (dipolar), and surprisingly have a net NEUTRAL charge (This is definitely something to call home about). Of the 20 alpha-amino acids comprising us, people, humans, mammals, there are a handful that are nonpolar (including BCAAs such as Leucine, IsoL, Valine). Ok, by "nonpolar" I'm talking about the R-group (the functional group). Now, if we toss an AA into regular tap water (pH=7.0), that zwitterion is still there, acting as BOTH an acid and a base. It's flopping back and forth, trying to find an equilibrium. Such a confused molecule it is....it must have a woman in its life (ok, that wasn't called for. Yes it was.).
No let's take a strong acid dump some into the water which has the Amino acid floating around. Now we're basically adding protons (H+), increasing the acididititidity (acidity if you're smart) of the water. Remember that COO- in the zwitterion? Well it's still there and it likes H+, so ya, they're going to hook up and stuff.
(If you're still reading, you're a glutton for punishment)
So, what we have left is that cationic NH3+ in the zwitterion (well, it's no longer a zwitterion anymore, but who really cares). MMMMMM exciting.
Ok, what the hell were we talking about again? Oh ya.
So, with the amino acid in THIS state, to be quite honest with you, it actually might help with it's solubility (again, I said if you used a STRONG ACID, and I'm doubtful Ascorbic acid is strong). I believe that the addition of this acid would be helpful to the BCAA's solubility because the R-groups of of Isoleucine, Leucine, and Valine (3 popular BCAAs) are Non-polar, so if you want to get the amino acid to dissolve, it has to be polar, just like water. And if you add that acid to the mixture, remember it's going to leave you with a polar group on that amino acid. And as my heavy Chem. professor used to tell us, "LIKE DISSOLVES LIKE". So, polar substances dissolve polar substances.
You better call home for this too.
That's my $.10. Good luck. Oh, and I too have BCAA powder, and I don't mind that it doesn't dissolve. I just toss a good scoop into my mouth, swish with water, mash up the fluffy balls of AA that form, and choke it down 2x/day. Life is good.
:bruce2: ------
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