Kidney trouble on CEE (Creatine Ethyl Ester)

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  1. Quote Originally Posted by morpheus1914
    In my experience, kre-alkalyn forms of creatine are the only ones not to be metabolized by the body into creatinine. Otherwise, every other form of creatine is probably going to raise your creatinine to anywhere from 2.0 - 3.0. However, the kidney pain is not normal, and I would have that evaluated further. Do you happen to know your glomerular filtration rate??
    I dont know my glomerular filtration rate...how would I check this? Blood test?


  2. Yes. It's a caculation determined from simple serum chemistries. I would also check your BUN/Creatinine Ratio. The docs probably already figure this, but just to paint a bigger picture. Have you had a urinalysis done to check for protein or casts in your urine?
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  3. No, I have'nt.

    Got another blood test done today. Should have the results by friday. I will be interested to see if Pump Juice spikes my kidney function like CEE. I'll let you all know the results when I get them.

  4. Quote Originally Posted by doggzj
    How are you not pissing all day? I drink about a gallon a day and spend 10-15 trips in the bathroom to pee. I mean it would really hinder my life to drink more then I already do. Do you have like a superbladder?

    HaHa, WEll I do make alot of trips to potty, that is for sure, but I always make sure im near a bathroom were ever I go. I used to never drink water, so this is amazing for me that I can learn to appreciate it

  5. Quote Originally Posted by andhen2003
    hm, well this is all a bit scary. i had assumed that the safety track record of CEE was sort of equivalent to that of mono. i may rethink my use of CEE after reading this. it just gives a bit of an edge, so why take chances?

    ps if I had my kidney blow up to twice it's size, i wouldnt be hitting any type of creatine after that. you may have kidneys that are more susceptable to injury.



    That would be my decision as well.
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  6. Quote Originally Posted by andhen2003
    hm, well this is all a bit scary. i had assumed that the safety track record of CEE was sort of equivalent to that of mono. i may rethink my use of CEE after reading this. it just gives a bit of an edge, so why take chances?

    ps if I had my kidney blow up to twice it's size, i wouldnt be hitting any type of creatine after that. you may have kidneys that are more susceptable to injury.
    It was swollen...the way kidneys send to get when you start feeling that pain most think is lower back pain. Most people just dont get a sonogram done to see how much it swelled up. That said....you make a good point.

    I won't be using CEE anymore, but the jury is still out on the other forms of creatine. One thing is for sure though, my water intake will be increased by 1.5 gallons per day if I do decide to use other forms of creatine.

    I'll let you know what my blood test results are as soon as I get them...

  7. Well I received my results. My creatinine level was 1.4 on Pump Juice so I guess CEE is harder on ones kidneys.

  8. I too have been experiencing lower back pain and pain on my lower left hand side. I'm only taking CEE right now, so in comparing my experience with others it seems like I'm having some kidney irritation as well. Yes I have been drinking water like a fish too. I thought it might have been a liver problem. I'll discontinue and give it a few days before I call my doc.

    Also, as I was googling this earlier, it seems that your average CEE product already contains a good portion of creatinine in the tub. This is according to the kre alkalyn website and the third party analysis posted on bodybuilding. com. Could ingesting so much creatinine straight off the bat be the culprit of these kidney problems?

  9. Quote Originally Posted by ocyeoman
    I too have been experiencing lower back pain and pain on my lower left hand side. I'm only taking CEE right now, so in comparing my experience with others it seems like I'm having some kidney irritation as well. Yes I have been drinking water like a fish too. I thought it might have been a liver problem. I'll discontinue and give it a few days before I call my doc.

    Also, as I was googling this earlier, it seems that your average CEE product already contains a good portion of creatinine in the tub. This is according to the kre alkalyn website and the third party analysis posted on bodybuilding. com. Could ingesting so much creatinine straight off the bat be the culprit of these kidney problems?
    interesting post

  10. This is a real eye-opener. I've been on CEE for over 1 year now, although I typically keep it to within 1-3 grams per day. In checking my recent bloodwork, my creatinine is 1.1-1.2 mg/dl.

  11. Quote Originally Posted by SubliminalX
    This is a real eye-opener. I've been on CEE for over 1 year now, although I typically keep it to within 1-3 grams per day. In checking my recent bloodwork, my creatinine is 1.1-1.2 mg/dl.
    hmmm thats very interesting

    it would be nice to see more blood work from other people

  12. I found this study while snooping around the FDA website: http://www.fda.gov/ohrms/dockets/doc...-06-vol181.pdf

    It details a study in which five subjects were administered 5g of CEE a day. Of the five one developed higher than acceptable serum creatinine levels of 1.7 mg/dl. Not extraordinarily high, but it does give one pause. If an adverse effect occurred in such a small sample size what does that say of the population at large? What would happen with a much larger sample size? I think we are seeing the effects.

    There seems to be a lot on the FDA website about CEE. Have a look see if interested. A few papers present data that cast aspersion on the stuff. I won't go there because it is off topic and sure to spark a flame, but much of the data suggests that creatine ethyl ester is at best just crappy monohydrate or at worst mostly ineffective. A total bummer for me. I just bought a kilo in bulk. I guess I'll be tossing it.
  13. Thumbs up


    It's great to see a board like this that is so helpful and allows others to learn and benifit from mistakes and successes we have all experinced. Thanks for all the great responses! I will be sticking to Creatines like "Pump Juice" from here on out as I like my kidneys.

  14. Quote Originally Posted by workin2005
    It's great to see a board like this that is so helpful and allows others to learn and benifit from mistakes and successes we have all experinced. Thanks for all the great responses! I will be sticking to Creatines like "Pump Juice" from here on out as I like my kidneys.
    Yeah, dude. I'm thankful too. I plan on switching to a kre-alkalyn product like Pump Juice too. I have some confidence in that stuff since it doesn't convert to creatinine. At least you just excrete excess creatine. I believe Pump Juice is pretty similar to Get Diesel Nos Ether and I hear great things about that. I may give it a shot.

  15. I think if you are going to use CEE, then you are better off using it for short periods of time(1 month) then take some time off. There is not any evidence to support year round usage of CEE without health effects.
    Renal issues should always be taken seriously.

  16. Of course what someone decides to put in their own body is their own perogative, but why use CEE at all if the substance has been proven neither safe nor effective? After researching it a bit I feel kind of like a dope for just aimlessly following the crowd. I thought I was already careful, but I think I'll be even more judicious in my supplement use in the future.

  17. Pardon my ignorance but what form of creatine is Pump Juice?

  18. Quote Originally Posted by ocyeoman
    Of course what someone decides to put in their own body is their own perogative, but why use CEE at all if the substance has been proven neither safe nor effective?
    I'd say that CEE has been effective for me in the lower doses. At full doses of BSN Cellmass or Muscletech CEE though, I tend to get headaches during workouts. Otherwise, I think CEE is a good muscle volumizer that is good for hypertrophy IMO. And looking at the various forums, CEE is one of those supps that most everyone feels positively about. This thread is one of the rarer reports I've seen discussing problems with CEE.

  19. Earlier this week I ordered a bottle of the All American EFX liquid kre-alkalyn creatine, lemon flavored. I will let you know how it works.

    Im also starting doggcrapp training. Im very excited!

  20. Quote Originally Posted by SubliminalX
    I'd say that CEE has been effective for me in the lower doses. At full doses of BSN Cellmass or Muscletech CEE though, I tend to get headaches during workouts. Otherwise, I think CEE is a good muscle volumizer that is good for hypertrophy IMO. And looking at the various forums, CEE is one of those supps that most everyone feels positively about. This thread is one of the rarer reports I've seen discussing problems with CEE.
    You are right. I misspoke somewhat. What I meant to say was that it hasn't been as proven effective as regular old monohydrate which is generally accepted to be safe. I had pretty good results with CEE myself besides the pain and discomfort that has recently arisen. I hadn't taken creatine since high school and forgot how beneficial it could be.

    However, I know there is a lot of difference on opinion on this, but I've interpreted the various analyses of CEE by various groups mean that CEE is just impure (i.e., filled with creatinine) creatine monohydrate. Obviously this could still give you results. Aside from the kre-alkalyn website which although poses a compelling argument obviously has a commercial interest in bashing CEE, the "Clayton South Health Facts" section of bodybuilding .com has some damning analyses of CEE as well. It's somewhat ironic because the article tries to sell CEE by strongly asserting its legitamacy and amazingness and then offers links to COAs to prove the point. However, the COAs actually say that the CEE product is simply monohydrate plus creatinine. Here is the most damning report: http://www.bodybuilding.com/store/ceereport_part2b.jpg
    Here are all the third party reports: Bodybuilding.com - Is CEE fake?

    Like I said earlier, there is other stuff on the FDA website and google scholar that gives me further pause on CEE. I respect the fact that people like it. I liked it too. I just choose now to believe that it isn't what it's cracked up to be.

  21. there's some real informative stuff here on this thread, very positive

  22. I am thinking about ditching my CEE as well. Good post. Only bought 200 grams so no big deal.

  23. Or, people could take smaller doses of the stuff (90% monohydrate, 10% CEE).

  24. Quote Originally Posted by yeahright
    Or, people could take smaller doses of the stuff (90% monohydrate, 10% CEE).
    That's a possibility. BSN has an OK rep, and I would think that their stuff contains near 100% of the reported amount of CEE. But it's possible that Cellmass is impure, and my concentration of CEE has been much lower than I thought. This is one reasonable explaination for my normal serum creatinine levels.

    I'm switching over to DS Exceed, which has a CofA that confirms 100% of the reported CEE content. I'm gonna go light on the stuff, like 1g ED or EOD. But at the same time, because of the purity, there may be very little to no creatinine in it.
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