anyone here ever use targex1 ?

  1. anyone here ever use targex1 ?

    I did a search but did not find much info on it? I think Carlito is the one who makes it, just curious if anyone has any feedback to share?

  2. I would like some to hear info or feedback on this one as well.

  3. no one here has anything to say?

  4. I'll give it a shot for my thighs in about 10 weeks, if you're patient I'll let you know how good it is

  5. well I got some on order, so I will be trying by end of week

  6. Giant Nutrition makes a product with the active in Target X in it... sold commercially.

    The Historic PES Legend

  7. whats the name of it

  8. Its something like liposolve or something like that... its on the site.

    The Historic PES Legend

  9. Sorry bro, but all I can think about is the chick in your avatar.

  10. Nope still thinking about her.

  11. Okay now Im ready.

    Targex1: (Glycyrrhetinic acid in a topical oil based gel.)

    Here's a study on Glycyrrhetinic acid from pub med:

    Steroids. 2005 Jul;70(8):538-42. Epub 2005 Apr 12.

    Glycyrrhetinic acid, the active principle of licorice, can reduce the thickness of subcutaneous thigh fat through topical application.

    Armanini D, Nacamulli D, Francini-Pesenti F, Battagin G, Ragazzi E, Fiore C.
    Department of Medical and Surgical Sciences-Endocrinology, University of Padua, Via Ospedale 105, 35100 Padua, Italy.

    Cortisol is involved in the distribution and deposition of fat, and its action is regulated by the activity of 11beta-hydroxysteroid dehydrogenase. Glycyrrhetinic acid, the active principle of licorice root, blocks 11beta-hydroxysteroid dehydrogenase type 1, thus reducing the availability of cortisol at the level of adipocytes. We evaluated the effect of topical application of a cream containing glycyrrhetinic acid in the thickness of fat at the level of the thigh. Eighteen healthy women (age range 20-33 years) with normal BMI were randomly allocated to treatment, at the level of the dominant thigh, with a cream containing 2.5% glycyrrhetinic acid (n=9) or with a placebo cream containing the excipients alone (n=9). Before and after 1 month of treatment both the circumference and the thickness of the superficial fat layer of the thighs (by ultrasound analysis) were measured. The circumference and the thickness of the superficial fat layer were significantly reduced in comparison to the controlateral untreated thigh and to control subjects treated with the placebo cream. No changes were observed in blood pressure, plasma renin activity, plasma aldosterone or cortisol. The effect of glycyrrhetinic acid on the thickness of subcutaneous fat was likely related to a block of 11beta-hydroxysteroid dehydrogenase type 1 at the level of fat cells; therefore, glycyrrhetinic acid could be effectively used in the reduction of unwanted local fat accumulation.

    Publication Types:

    * Clinical Trial
    * Randomized Controlled Trial

    PMID: 15894038 [PubMed - indexed for MEDLINE]

    The results are not systemic. They are strictly local. Pretty cool if you ask me. I want to pick some up this summer. It's mostly for when your allready under 10% and want to get rid of the trouble spots.

    Anyway back to thinking about chic in Goes4ever's avatar. Ahhhhh..... Thats better..........JK........but not really.

  12. Uni - COME ON!

    Goes4 has only had that Av since I first joined.

    Dude. I mean really. Get with the hot chick avatars!

  13. What is targex1?

  14. I got mine yesterday and used it before bed and again this morning, it has a very pleasant citrus smell, rubs on smooth although a bit oily, takes awhile to dry, I will report back my results

  15. What concentration is manufactured to?

  16. Quote Originally Posted by bbuck
    What concentration is manufactured to?
    not sure what your asking bro?


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