Trying to decide what to run... I have never ran thyroid hormone before and I’m concerned about the T3 rebound.... also from what I have heard if you don’t do it rite diet and such, you end up just looking the same just smaller Because of muscle wasting...
I’ll run Mk2866 and Mk677 as well
So I’ve been bouncing back and forth between t3 and t4
I'm gonna go against the grain here. Here's the thing. I'm usually the type of guy to tell you that if something works, it works and too often in the supplement world we give products the pass with, "Well, everyone is different." This is typically bullsh!t and if it works in someone, it should work in everyone, at least to some degree.
Having given that caveat, well, with T3 - it's the one compound I think stands out the most as to different people responding differently to it. Some people SWEAR they lose muscle fast on it. I think this is somewhat blown out of proportion and here's why.
1. Most people assume they carry more muscle than they do. Fat over your muscles can make your muscles look bigger. If you are on T3 and lose fat quickly, you will look much smaller. But you didn't lose muscle, you just lost fat. But it's hard for us to accept this because we all think we should look bigger than we are naturally capable of. Steroids are required to get the look you see on a lot of movie stars even - it's not natural. And if you respond well to T3, this "muscle wasting" fallacy will be more pronounced as you will be burning fat more quickly.
2. You will deplete glycogen while taking T3 and this will, at first, create a rapid drop in strength. When I started taking T3, this was the most pronounced effect I saw - especially at upper doses. I lost a lot of glycogen and the strength and size that went with it. But it wasn't "muscle loss" - it is a temporary effect from depletion. And it was rapid. It is similar to going on an extreme diet, except instead of happening over 1-2 weeks it happens over 2-4 days. Of course most people will freak when this happens, but then it stops and your strength stabilizes and you can actually start to see strength gains again at this lower point, and then once you stop and/or carb up, it comes back fast.
In other words, I think that the need for anabolics on T3 is more perception than reality. If you can mentally get past the fact you are gonna lose some strength for a while and will need to be working at a lower output while on it, you will be fine.
For me, I've taken large doses and barely notice anything. I notice glycogen depletion the most. Fat loss is minimal for me, even at 200 mcg a day - which I would NOT recommend you do without patience and experience. Some people will be hyper responders and won't be able to take 50 mcg without having a rapid heart rate, and I am at the other end of the spectrum where I barely respond.
at 150-200 mcg I noticed my resting heart rate on my fitbit went from 49-52 up to about 62 BPM. I also had a much improved mood and less "depression" - not saying I even have depression, just that I was better able to deal with things and less overwhelmed, improved mood, less moodiness when under stress, etc. I can be pretty dark at times when I'm under stress and I'm not as bad.
As for T3 and T4 - if you're looking for fat loss, just go to T3. Both will shut you down, T3 will have a stronger impact on fat loss. Plus, IMO, the shut down can actually have some benefits as sometimes, during a diet, we don't get proper nutrition 100% and the conversion of T4 to T3 doesn't always go so well...at least in theory, although I don't 100% believe the reverse T3 stuff either.
