This is true, I just am very cautious of medications, my mom has been on countless medications for anxiety now for years, always saying they about to start cutting back, but it never happening. Now, her symptoms are much much more severe than mine are. But, still.
I haven't noticed any differences in mood or anything since starting the Glycopyrrolate, so I don't think that is the cause. It may have gradually started increasing my symptoms but that is difficult to tell.
I have used GABA a few times, mostly mixed into other products. I don't think I have supplemented with it alone though.
The Acetylcholine issue may or may not be an actual issue and it is hard to tell.. I don't notice any brain fog or headaches ever since starting the Glycopyrrolate that would suggest too low of Acetylcholine levels.
I don't smoke, I drink 2-4 cups of coffee a day, maybe add in a preworkout once or twice a week. No other major stimulants though.
My diet is decent, I have been intermittent fasting for a while, only eating from around 5:00pm-11:30pm. Sometimes I will eat a snack mid day, but I am about to start eating breakfast and a lunch again so we will see if that helps energy levels. I notice if I fast during the day, I'm not as hungry at night, but if I eat one meal or a small snack during the day, I end up much hungrier earlier than I normally would.
All interesting info - the Glycopyrrolate does not cross the BBB so it may not have any effect on mood and may be targeted toward your peripheral system, which would actually be desired for the hyperhidrosis. Why mess with your brain if you can solve the chemical action in the body without messing with it.
2-4 cups of coffee isn't a lot for most people, I drink way more and take a ton of caffeine, but I have a high tolerance. But caffeine does block adenosine receptors; which maybe you don't clear that so well and it keeps you awake? A day or two without caffeine may have a huge impact on your sleep.
Another thing that helps me a lot, not so much with falling asleep, but with staying asleep is ZMA.
Restful sleep can have a huge impact, which might be most of what you are feeling with the happiness/energy the next day.
Have you had blood work done? How are your red blood counts?
I am curious to see how you feel if you eat more breakfast. I've been on hard diets off and on for a couple years, including a PSMF. I've noticed the opposite - sometimes I can go all day without eating and this usually triggers over-eating at night. I'm currently thinking a lot about the circadian rhythm and how sleep/wake may effect appetite more than we realize. We know that too little sleep can effect grehlin levels and increase hunger; I wonder if even more goes into it. I'm trying to eat more like a farmer - a bigger breakfast for a big work day, nothing or maybe some small amounts of protein through the day/afternoon if I get hungry, and a more reasonable dinner - which means about 50% of my calories for breakfast and 50% for dinner, or maybe 45/45 if I have a snack. I'd like to shift that more toward eating early in the day and see how that goes. It will be interesting if eating earlier instead of IF will have an effect on you that is unexpected.
Bulk gaba is super cheap.
Odorless, colorless, and tasteless. If u take it, let's say 2 nights after your benzo dose, you would be trying a cheap and safe experiment.
HIT4ME do you know of the general consensus on sleep cycles w benzos? I remember reading about how lousy they were with the dedicated sleep aides (ambien, lunesta, etc), significant negative impact with benzos, but surprisingly almost normal w off label trazodone use... my subjective experience is in agreement, so my confirmation bias is in full force LOL
I honestly don't know much about benzo's directly - I would have to research and I have no experience with it. I will say that the more I look at this stuff, and I am far from a trained medical professional, the less I realize we actually know. My grandmother is a major factor behind most of my recent research - she is 91 and can't walk on her own anymore. She is on opioids for pain and has a ton of sides from it that even the doctors seem to ignore. Researching opioids has shown me how much doctors prescribe things that are only partially understood and think they work one way without realizing the consequences. For instance, long-term opioid use may actually cause INCREASES in pain; which is contradictory to the reason you are prescribing them to begin with. This is different than tolerance - it is an issue where the patient becomes sensitive to pain because of the opiates and increasing the dose actually creates more pain. Whether this actually happens is debated but it has been observed as far back as 1870 by doctors using morphine. It just goes to show that sometimes things work one way for a while, but then it goes to far and you get contradictory effects.