Higher doses of betaine (TMG) in the 6-8g/day range

[Justlooking5]

I've been taking betaine anhydrous (TMG) at about 1.5g twice per day for about 8 weeks or so. While the effect may be subtle, I don't think I have noticed anything substantial from it at this dose.

Therefore, I decided to try taking between ~5-8g day. This morning I took a dose of 4g, and noticed a mild increase in energy, and a pretty big pump for a few hours afterwards.
Any thoughts on taking betaine anhydrous at around 8g per day instead of 2-3g? In other words, any reasons not to see if more has a more significant effect?

Studies I've read so far seem to suggest it is safe at doses quite a bit higher than 8g:

A 1-y pilot study (150) showed that betaine (20 g/d) is safe and well tolerated and leads to significant biochemical and histologic improvement in patients with NASH.

http://ajcn.nutrition.org/content/80/3/539.long

 

[Adizzle1]

TMG can cause GI upset or diarehea if dosed to high in some individuals so I probablly wouldnt take 8g all at once. Splitting the doses may be a plausible solution.

 

[Justlooking5]

That's my plan, to do about 3-4g twice per day. Any thoughts or has anyone tried this?

 

[Justlooking5]

I'm also three weeks in with PA from Fearn's, and I think I'm getting strength increases from PA for sure, but today I hit PRs (not all time but since I've been bulking again) in literally every exercise I did except one. Great pump and weights felt lighter. Some mild stomach bloating but nothing significant.

 

[cobri66]

There's a study done on horses..( I know..Horses) but there was an amplifying effect when Betaine was taken in conjuction with CLA..pretty good fat burning took place..FWIW

 

[muscleupcrohn]

There's a study done on horses..( I know..Horses) but there was an amplifying effect when Betaine was taken in conjuction with CLA..pretty good fat burning took place..FWIW

Link to said study?

 

[criticalbench]

I've read of doses in upwards of 10g..

GI side effects are always possible though.

 

[cobri66]

Link to said study?

my bad..done on pigs

Synergistic_effects_of_betaine_and_conjugated_linoleic_acid_on_growth_and_carcass_composition_of_growing_Iberian_pigs

google that..I can't post links yet cuz of post count

 

[muscleupcrohn]

my bad..done on pigs

Synergistic_effects_of_betaine_and_conjugated_linoleic_acid_on_growth_and_carcass_composition_of_growing_Iberian_pigs

google that..I can't post links yet cuz of post count

Thanks. I was hoping it was on horses; I've been doing a lot of research on supplements for horses lately (not to extrapolate to humans, but to use for horses).

 

[cobri66]

Thanks. I was hoping it was on horses; I've been doing a lot of research on supplements for horses lately (not to extrapolate to humans, but to use for horses).

sorry for my bad memory

 

[Dfin0490]

Do you have to take it everyday to get the maximum effect from it whereas every other day or just on workout days do not get a benefit?

 

[Justlooking5]

I read the same study. I like betaine at dosages over 5g/day (up to 8-10g so far), but for some reason I think it makes me feel headache-y and kind of run down... not sure why exactly, but it does seem to increase muscle fullness, growth and strength a bit more when you increase the dose.

 

[Dfin0490]

Gets kinda spendy at that dose?

 

[Justlooking5]

Actually not in comparison to most other supps. I've been getting betaine powder from bulk supplements on Amazon, like 11 dollars for 250g.

 

[Dfin0490]

Nice gonna look into that for sure. Good call

 

[heavylifter33]

TMG can cause GI upset or diarehea if dosed to high in some individuals so I probablly wouldnt take 8g all at once. Splitting the doses may be a plausible solution.

I accidentally took around 6g of Betaine and got really nauseous and then had some serious GI distress. Was not fun. I add SNS betaine to certain pre workouts and wasn't paying attention and added it to a pre that already had like 3g in it. Won't be making that mistake again.

 

[JudoJosh]

Do you have to take it everyday to get the maximum effect from it whereas every other day or just on workout days do not get a benefit?

My guess is, possibly. It is a saturation type compound so taking a higher dose every other day could lead to similar results as daily dosages

 

[JudoJosh]

I accidentally took around 6g of Betaine and got really nauseous and then had some serious GI distress. Was not fun. I add SNS betaine to certain pre workouts and wasn't paying attention and added it to a pre that already had like 3g in it. Won't be making that mistake again.

It's an osmotic compound, hence the intestinal distress when dosed too high

 

[VaughnTrue]

I'm a big fan of TMG. If you combine Hemavo2 with our upcoming Finish Line, you get a full 5,000mg/day in total.