I've always had a kind of paradoxical reaction to Mucuna that leaves me in a kind of distracted mood and after a few days of taking it, my libido is in the dumps. It's possibly an indirect reaction more than a direct causation, but it's still there and it's so strong and happens so consistently that I don't even bother with any Mucuna containing supplements.
So yeah, even if the opposite happens with most people, what you describe still can happen. Anything that affects neurotransmitters & bodily hormones can cause any number of unpredictable effects in rare cases.
As another example -- even a tiny bit too much DAA can leave me feeling over-stimulated, unable to sleep, and stimulated in a way that makes it hard to focus. This is a rare reaction, but if you pay attention long enough on user reports, you do see it pop up now and again.