For long term anti-inflammatory I would have to go to proteolytic (systemic) enzymes hands down. No LD-50, they can tell the difference between good and bad CIC's (Circulating Immune Complex) unlike certain products-COX inhibitors, and under 27 are your first line of defense against inflammation naturally. I also do use curcumin here and there and ginger standardized for 5% gingerols, but not on a daily basis anymore. I've done the whole fish oil, krill oil, tart cherry juice, etc. thing and it never had as a profound effect. The negative is that systemic enzymes are expensive and there are not a lot of good products out there so it is easy to get burned. As far as antioxidant goes, I just use good ol' fashion ascorbic acid. It is dirt cheap and I can combine it with my magnesium oxide (also dirt cheap) for absorption to create a magnesium ascorbate. I have also used astaxanthin and many other things that just happen to be an antioxidant as well, but always go back to ascorbic acid if we are talking long term.