50 day break from ArA necessary?

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    Or would 3-4 weeks be okay? I think I understand the point of cycling off ArA supplementation, but it seems that once you came off of it, after a couple weeks of exercise, that you'd simply revert back to normal levels. So why the 50 day recommendation? Does it have to do with the inflammation that ArA causes

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    The 50 day brake is to keep the platelet aggregation at a minimum.
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    4 weeks seems to be plenty for everyone I know that has used it. I have not tried it yet so cannot give a personal testimony, but that is what I have seen.
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    Quote Originally Posted by Type O Hero View Post
    Or would 3-4 weeks be okay? I think I understand the point of cycling off ArA supplementation, but it seems that once you came off of it, after a couple weeks of exercise, that you'd simply revert back to normal levels. So why the 50 day recommendation? Does it have to do with the inflammation that ArA causes
    The 50 days recommendation is because that's the longest they've ran it for in the study. I would guess that it would make very little sense to run it much longer than that because there's going to be a point where your muscle cell membranes would simply not be able to make use of the ArA and most likely this fatty acid will get used in the body for other purposes. In other words, there's either very little benefit or not benefits after a certain point.
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    How significant is the platelet aggregation?
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    Quote Originally Posted by nattydisaster View Post
    How significant is the platelet aggregation?
    The data I believe suggests that even up to 1.5 grams a day of ArA for the 50 day length actually doesn't show to have any effect on platelet aggregation (Nelson, GJ; Schmidt, PC; Bartolini, G; Kelley, DS; Kyle, D 1997).

    It's also been shown in another study that up to 2 grams a day of ArA for 50 days doesn't cause out of the norm systemic inflammation.
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    This has been discussed in other threads as well, I believe...fwiw, last couple of ArA runs I've done, I've just stuck to 1.5g preWO, 4-5x's week for a total of 3 bottles of X-gels...and not worried about 50 days only...plus I hate storing opened, half full/empty bottles of anything...
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    As others have mentioned, due to ArA being extremely safe you wont be in any sort of danger. The reason for the label recommendation to cycle 50 days on and 50 days off is that it will take some time to deplete the ArA from your skeletal muscle after ending your cycle. You dont just go off and a week or two later you have depleted most of it, it takes time and many workouts.
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    Think of it in terms of cost:benefit, and it will make a lot more sense to you. It's not due to some sort of health or safety reasoning.
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    Quote Originally Posted by Synapsin View Post
    Think of it in terms of cost:benefit, and it will make a lot more sense to you. It's not due to some sort of health or safety reasoning.
    Well said.
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    I just take plavix and stay on year round..


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    Quote Originally Posted by criticalbench View Post
    I just take plavix and stay on year round..


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