Higher ArA dosage, or ArA stack?
- 01-27-2014, 07:10 PM
- 01-27-2014, 11:25 PM
01-28-2014, 06:01 AM
01-28-2014, 09:33 AM
Here's the entire first post from Neuron on the aforementioned thread:
"I made a cursory glance into the X-Factor thread and I didn't see any suggestion on when to take X-Factor, or other Arachidonic acid products, so here is my suggestion.
After ingestion, fatty acids like arachidonic acid are emulsifed and taken up into enterocytes where they are esterfied on a glycerol backbone to form a triglyceride. Next, the triglycerides and cholesterol esters are bound together to form a chylomicron. This entity can now diffuse into the lymphatics and then into the blood. Once in the blood, the chylomicrons are free to interact with various tissue receptors depending on energy homeostasis. When needed, they can interact with an enzyme called Lipoprotein Lipase (LPL) that will hydrolyze the triglycerides back into fatty acids to be used as fuel or for storage purposes.
The point being...
In which tissue the fatty acids are deposited is a function of the energetic state of the organism overall. In a post-prandial, high fed, state, the dominant hormone is insulin. Similarly, the only isoform of LPL that is active with insulin is located on adipocytes. It should be obvious now that consuming fats when eating will direct them to adipose. This isn't necessarily a bad thing in the context of fish oil, as adipose is now recognized as a great contributer to endogenous hormone production like the prostanoids.
In the context of Arachidonic Acid, the final destination should be skeletal muscle. Luckily, there is an energetic state which favors fatty acid delievery to this tissue: Exercise (or acute starvation) . In an exercise-induced environment, LPL on skeletal muscle becomes active which serves as an adjunct to glycolysis for the TCA cycle via beta-oxidation. Similarly, the enzyme DGAT also becomes active in skeletal muscle which functions to store excess fatty acids as triglycerides. Since both of these enzymes are heavily active during exercise, it is clear that an excess of fatty acids are being removed from blood plasma into skeletal muscle as a reservoir (this also serves to decrease insulin insensitivity ).
Based on these observations
To maximize ArA supplemention it is advisable to supplement 30-40 minutes prior to exercise in order to ensure plasma delievery of ArA and also to reduce exercises effects on gastric motility."
01-28-2014, 10:18 AM
Happy to hear that the stack I'm starting in a couple of weeks should be pretty kick ass.
ArA + ABE + GMS + LCLT. (maybe Amino IV, too)
01-28-2014, 10:19 AM
01-28-2014, 10:37 AM
01-28-2014, 11:12 AM
Serious Nutrition Solutions Representative
01-28-2014, 11:43 AM
01-28-2014, 12:03 PM
01-28-2014, 12:12 PM
01-28-2014, 01:10 PM
What are the conclusion on the carbs with ARA?
I take 25g Glycofuse with my ARA + PWO + LCLT + GMS + AminoIV pre-workout and 25g Glycofuse + AminoIV intra-workout.
01-28-2014, 01:34 PM
01-28-2014, 03:51 PM
01-28-2014, 04:02 PM
Im running ArA with Glycergrow & hemoval and ABE, except ive been dosing ABE with my biggest meals... gotta start dosing PWO I suppose
01-28-2014, 04:45 PM
01-28-2014, 06:02 PM
Darren and NP are too awesome, still selling X-Factor and XFA for right around $30!
Molecular Nutrition - Unlevel The Field
X-Factor: THE Most Scientifically Valid Muscle Builder, Ever!
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02-03-2014, 06:46 PM
02-03-2014, 06:58 PM
02-03-2014, 08:18 PM
02-03-2014, 08:24 PM
02-03-2014, 08:36 PM
02-03-2014, 08:43 PM
02-04-2014, 03:25 AM
But for the last time (and I mean the last time, not to you EBF, but to people asking the Qs as I've probably said this 25+ times now in the past month), if you are exercising, carbs/amino acids consumed with ArA won't matter. So take them all preworkout if you want and get to it
02-04-2014, 03:35 AM
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