That is a big stretch to say that leucine increases insulin same as carbs. Absolutely not. The insulin spike is significant but not near as much as an equal carb dose. Additionally, carbohydrate induced insulin response is biphasic, with the stored insulin in the pancreas being released immediately and sometime after that, insulin is produced by the pancreas and keeps being produced until the glucose clears. This secondary release of insulin is actually the comparatively larger release. Amino acids like Leucine only cause the initial release of stored insulin, but there is no biphasic response, no sustained release. So in all actuality, insulin release in response to leucine is very different from carbohydrate. As far as glutamine & glycine restoring glycogen; they can through gluconeogenesisâ?¦ but not as well as carbohydrate. Carbohydrates from diet can get into the bloodstream at a rate of about 50g/hour I believe whereas the maxed out rate of gluconeogenesis is about 5g/hour. So noâ?¦ they donâ??t restore glycogen as fast