Do-Not-Mix supplement/ingredient list.

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    Been wanting a topic made for this for a while I would love to compile a list of ingredients/supplements that should not be mixed either for safety or efficiency reasons.

    I will kick it off:

    ARA with anti-inflammatories (cissus, fish oils, etc.)

    Calcium inhibits the absorption of some minerals such as iron, reduces effectiveness of many sleep aids (ZMa), some antibiotics.

    Phytic acid (common in foods like oatmeal) will block absorption of many minerals as well, save your multivitamins for later in the day if you enjoy an oatmeal breakfast.

    Dendrobium alkaloids + beta alanine

    Tyramine + yohimbe

    Icariin + nitrates

    Prohormones/androgens + blood thinners
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    Quote Originally Posted by Driven2lift;
    Phytic acid (common in foods like oatmeal) will block absorption of many minerals as well, save your multivitamins for later in the day if you enjoy an oatmeal breakfast.
    First time I heard this, that kinda sucks..?
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    Knowledge is power, now you know to take it separate. I found out through the forum that I had been timing a few things wrong, for example taking cissus post workout.

    Nothing worse than spending good money on supplements just to waste them or cause detrimental effects.
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    The list of contraindications is too massive unfortunately
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    I always stay away from mixing is Icariin and Nitrates, also Viagra and Nitrates, it can lower blood pressure too much.

    I remember with the old meso formula back in the day had icariin & nitrates, their was enough reports back about feeling dizzy after using the 2 ingredients together.
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    Quote Originally Posted by mr.cooper69 View Post
    The list of contraindications is too massive unfortunately
    If we can get the most common mistakes made with mixing I would be happy. I recall a recent post of yours regarding beta alanine but can't find it now
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    Subbed for savings and added efficiency... Good thread idea
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    Tyrosine & yohimbe is is no no.
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    I have always dosed T2 products on an empty stomach as that is the way T3 and T4 needs to be dosed. Not sure if there is anything concrete to support this but it makes logical sense.
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    Quote Originally Posted by schizm View Post
    Tyrosine & yohimbe is is no no.
    Would you mind enlightening as to why?
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    Has anyone heard of agmatine + d-aspartic acid not to be mixed?

    Pretty sure Neuron ( I think) dispelled it.
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    Quote Originally Posted by booneman77 View Post
    Would you mind enlightening as to why?
    I would also like to know, I do it all the time...
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    Quote Originally Posted by Driven2lift View Post
    If we can get the most common mistakes made with mixing I would be happy. I recall a recent post of yours regarding beta alanine but can't find it now
    Here it is: (From Coop)

    "dendrobium alkaloids (namely dendrobine) should not be combined with beta-alanine due to antagonistic reactions/nausea"
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    Quote Originally Posted by booneman77 View Post

    Would you mind enlightening as to why?
    Crap, I may have meant tyramine/yohimbe...nattyd had a pretty in depth reason/post as to why, let me see if I can copy/pasta that....sorry guise..
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    Prohormones/Androgens and Coumadin/Bloodthinners. Apparently test increases the potency of the bloodthinners making your blood too thin. I was six days into a prohormone cycle last year when I pulled a hamstring. My blood had gotten so thin that the muscle wouldn't stop bleeding from the inside to the point where my entire leg from glute to ankle was black and blue. Hands down the most painful injury of my life. Required a blood transfusion and 10 days in the hospital. If you ever get prescribed bloodthinners get off your cycle immediately and inform your doc.
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    Cissus and Sulbutiamine

    They taste too damn bad
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    GMS and water ha
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    Subbed for more info, wish I had more to contribute to this but I got nothing at the moment.
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    Quote Originally Posted by booneman77 View Post
    Would you mind enlightening as to why?
    Quote Originally Posted by alwaysfirst View Post
    I would also like to know, I do it all the time...
    Quote Originally Posted by schizm View Post
    Crap, I may have meant tyramine/yohimbe...nattyd had a pretty in depth reason/post as to why, let me see if I can copy/pasta that....sorry guise..
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    Quote Originally Posted by ddfox View Post
    Here it is: (From Coop)

    "dendrobium alkaloids (namely dendrobine) should not be combined with beta-alanine due to antagonistic reactions/nausea"
    Dendrobium alkaloids should not be combined with your supplement consumption due to waste of money reactions.

    FTFY

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    Quote Originally Posted by Driven2lift View Post
    Been wanting a topic made for this for a while I would love to compile a list of ingredients/supplements that should not be mixed either for safety or efficiency reasons. I will kick it off: ARA with anti-inflammatories (cissus, fish oils, etc.) Calcium inhibits the absorption of some minerals such as iron, reduces effectiveness of many sleep aids (ZMa), some antibiotics. Phytic acid (common in foods like oatmeal) will block absorption of many minerals as well, save your multivitamins for later in the day if you enjoy an oatmeal breakfast.
    So with the phytic acid, is it right it just blocks some copper, zinc, magnesium and calcium? Or vitamins and other minerals aswell??
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    Initial post updated with all additions so far. I will update when I can, I hope we can keep this list going
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    Quote Originally Posted by De__eB View Post
    Dendrobium alkaloids should not be combined with your supplement consumption due to waste of money reactions.

    FTFY


    If you happen to be a rat, one specific alkaloid may improve vision

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    The first post should read tyramine and yohimbe as it has what they call a "cheesing effect", not tyrosine and yohimbe.
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    Awesome idea for a thread. Keep updating the first post.

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    Curios to see how long you should wait before taking a Viagra cialis or any other pde5 inhibitor (icariin ect) when using nitrates. When I use Icariin late in the day I feel poor erection quality use to the combo but nothing if I use one or the other
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    Quote Originally Posted by 3clipseGT View Post
    The first post should read tyramine and yohimbe as it has what they call a "cheesing effect", not tyrosine and yohimbe.
    Both tyramine and tyrosine with yohimbine cause this effect
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    great topic. sub.
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    Definitely subbed
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    Quote Originally Posted by nattydisaster View Post
    Both tyramine and tyrosine with yohimbine cause this effect
    Aahh well i stand corrected. My apologies to the op for the misinformation.
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    Aside from anecdotal evidence a little substantive supporting data would be greatly appreciated IINTMTA
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    Definite Sub! great idea!!
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    Quote Originally Posted by David Dunn View Post
    Aside from anecdotal evidence a little substantive supporting data would be greatly appreciated IINTMTA
    The FDA released a statement on combining tyrosine + yohimbine, and the dendrobine/BA thing was from a 50+ year old paper that took some major digging
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    I'm sure its common knowledge, but just in case someone missed it: Grapefruit juice, or the P450 enzyme inhibiting substituents of grapefruit, is generally best avoided when taking practically any medicine.
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    Quote Originally Posted by David Dunn View Post
    IINTMTA
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    Quote Originally Posted by PharmAnalyst View Post
    I'm sure its common knowledge, but just in case someone missed it: Grapefruit juice, or the P450 enzyme inhibiting substituents of grapefruit, is generally best avoided when taking practically any medicine.
    Nobody likes grapefruit anyways. You know?!?
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