Do-Not-Mix supplement/ingredient list.

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    PharmAnalyst's Avatar
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    Quote Originally Posted by drewsicle3210 View Post
    Nobody likes grapefruit anyways. You know?!?
    True enough, but it seems like a lot of energy supplements started adding naringin and/or bergamottin at some point to prolong their effects/enhance bio-availability.

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    Quote Originally Posted by JudgementDay View Post
    I always stay away from mixing is Icariin and Nitrates, also Viagra and Nitrates, it can lower blood pressure too much.

    I remember with the old meso formula back in the day had icariin & nitrates, their was enough reports back about feeling dizzy after using the 2 ingredients together.
    So Appnut Drive and PES Enhanced is a bad idea?
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    Quote Originally Posted by Sprinterguy4 View Post
    So Appnut Drive and PES Enhanced is a bad idea?
    Icariin and nitrates should be fine. Icariin has 1/10th the potency of viagra. The issue with past icariin products is that the majority (yes, the majority, proven by studies) were spiked with clinical PDE5 inhibitors
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
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    Quote Originally Posted by Sprinterguy4 View Post
    So Appnut Drive and PES Enhanced is a bad idea?
    I wouldn't myself, when I repped for APS Nutrition had Icariin and Nitrates in Mesomorph, they had enough complaints about customers feeling light headed, so they removed Icariin. That was one of the main reasons why it was taken out of the formula.
    CORE NUTRITIONALS Representative

    If you have any questions feel free to email me at, tommy.day@corenutritionals.com
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    Quote Originally Posted by David Dunn View Post
    Aside from anecdotal evidence a little substantive supporting data would be greatly appreciated IINTMTA
    Quote Originally Posted by ricroc View Post
    What does this mean? A brand new supp? HAHA!
    If It's Not Too Much Trouble ---

    I have no idea what that 'A' is.
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    If It's Not Too Much To Ask
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    I took yohimbe bark and a couple of hours then drank some grapefruit juice. Never threw up so much in my life and just overall felt llike ****.
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    Quote Originally Posted by 51FTY View Post
    I took yohimbe bark and a couple of hours then drank some grapefruit juice. Never threw up so much in my life and just overall felt llike ****.
    Blame CYP2D6
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
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    What about an inhaler along with other beta2 agonists?
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    Anything to avoid on quetiapine or lorazepam? And no, I'm not crazy.

    I'm avoiding nootropics.
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    Look for drug interactions on drugs.com
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    So it must have happened on this board already... who has dabbled with viagra/cialis and potassium nitrate?
  13. Enhanced Body Formulations
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    Quote Originally Posted by them View Post
    So it must have happened on this board already... who has dabbled with viagra/cialis and potassium nitrate?
    If taking either or here's what I have done

    Kno3 3-4 hours prior. Seems half life of that is pretty short however what you will notice if you take them too close, atleast for me, you have a hard time maintaining or achieving desired outcome

    Cialis same deal however once taking cialis, remember it works for 36 hours. For me I was still able to take kno3 24 hours after taking a cialis

    Of course this isn't sound medical advice. But just telling you how I've played around with it
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    Quote Originally Posted by EBF Inc View Post
    If taking either or here's what I have done

    Kno3 3-4 hours prior. Seems half life of that is pretty short however what you will notice if you take them too close, atleast for me, you have a hard time maintaining or achieving desired outcome

    Cialis same deal however once taking cialis, remember it works for 36 hours. For me I was still able to take kno3 24 hours after taking a cialis

    Of course this isn't sound medical advice. But just telling you how I've played around with it
    I would not advise this...heavily contraindicated. Nitrates also have a much longer halflife than you think
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
  15. Enhanced Body Formulations
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    Didn't say it was right, was just giving my experience
    Enhanced Body Formulations Product Educator
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    Quote Originally Posted by EBF Inc View Post
    Didn't say it was right, was just giving my experience
    I'm not addressing other people, I'm addressing you. For your own safety, I encourage you to stop this protocol, even if nothing has happened as of yet
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
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    Yeh I am considering it as well. I only started K nitrate a few days ago. I had 4 caps spaced out 2 days ago (workout day), 4 spaced out yesterday, only one cap today around midday. Then I read PES message saying amino nitrates have a 8-9 half life.. DOH. I totally forgot I gotta be in banging mode tonight.

    I am tempted to have 5mg cialis tonight around 11pm. I just don't wanna die

    Relevant study:

    J Am Coll Cardiol. 2003 Nov 19;42(10):1855-60.
    Time course of the interaction between tadalafil and nitrates.
    Kloner RA, Hutter AM, Emmick JT, Mitchell MI, Denne J, Jackson G.
    Author information
    Abstract
    OBJECTIVES:
    This study was designed to determine the time course of nitrate interaction with tadalafil, a phosphodiesterase 5 (PDE5) inhibitor with a half-life (t(1/2)) of 17.5 h.
    BACKGROUND:
    The PDE5 inhibitors augment the blood pressure (BP)-lowering effects of nitrates, yet the time course of this interaction is unclear. Recent guidelines from the American College of Cardiology/American Heart Association recommend that nitrates be withheld for 24 h after taking sildenafil (t(1/2) = 4 h).
    METHODS:
    Male subjects (n = 150) received seven consecutive daily doses of placebo or tadalafil (20 mg). On day 7 and beyond, subjects received repeated doses of sublingual nitroglycerin (0.4 mg) after the last dose of placebo or tadalafil. After a 10- to 21-day washout period, subjects crossed over to either placebo or tadalafil, and nitrate dosing was repeated.
    RESULTS:
    In response to nitroglycerin at 4, 8, and 24 h, standing systolic BP fell below 85 mm Hg in more subjects on tadalafil compared with placebo (p < 0.05), with no difference in the response to nitroglycerin at 48, 72, and 96 h (p > 0.2). Similar observations were made for standing diastolic BP <45 mm Hg, decrease in systolic BP >30 mm Hg, and decrease in diastolic BP >20 mm Hg. Nitroglycerin also evoked greater mean maximal decreases in standing systolic BP at 8 and 24 h after taking tadalafil versus placebo (p < 0.02), with no significant difference at 48, 72, or 96 h (p > 0.49).
    CONCLUSIONS:
    The hemodynamic interaction between tadalafil and sublingual nitroglycerin lasted 24 h, but was not seen at 48 h and beyond. Similar to other PDE5 inhibitors, tadalafil should not be administered in combination with organic nitrates.
    Comment in
    Time course of the interaction between tadalafil and nitrates. [J Am Coll Cardiol. 2004]

    140mg of cialis in 7 days is pretty huge considering the looong half life, interesting that they applied nitroglycerin which is supposed to be potent in the nitrate world. But even so 0.4mg versus the probable 100mg of KNO3 still hanging around in my system.

    I reckon there are gonna be plenty of bros that will knock down a similar KNO3 dosing to me and hit the cialis in the evening... though do I wanna be one of the first to talk about it. Also on that Bioperine infused Vanillean which adds lovely CYP3A4 interactions, not to mention the BP lowering effects of forskolin today... I'll be fine but as they say safer than sorry.

    If anyone can get FT or has a more poignant study, please let me know.
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    I think I will tend to not having the cialis as I don't like the fogginess, light headacheyness and tired feeling the next day..

    If anyone can suggest any supps I can use to keep my Peter in fighting form tonight when I drink it would be appreciated
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    Agreed

    Quote Originally Posted by aaronuconn View Post
    Awesome idea for a thread. Keep updating the first post.
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    Recently i read too much flaxseed oil could hinder the absorption of long chained omega 3 fat acids from fish
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