Do-Not-Mix supplement/ingredient list.

Driven2lift

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Been wanting a topic made for this for a while I would love to compile a list of ingredients/supplements that should not be mixed either for safety or efficiency reasons.

I will kick it off:

ARA with anti-inflammatories (cissus, fish oils, etc.)

Calcium inhibits the absorption of some minerals such as iron, reduces effectiveness of many sleep aids (ZMa), some antibiotics.

Phytic acid (common in foods like oatmeal) will block absorption of many minerals as well, save your multivitamins for later in the day if you enjoy an oatmeal breakfast.

Dendrobium alkaloids + beta alanine

Tyramine + yohimbe

Icariin + nitrates

Prohormones/androgens + blood thinners
 

alwaysfirst

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Phytic acid (common in foods like oatmeal) will block absorption of many minerals as well, save your multivitamins for later in the day if you enjoy an oatmeal breakfast.
First time I heard this, that kinda sucks..?
 
Driven2lift

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Knowledge is power, now you know to take it separate. I found out through the forum that I had been timing a few things wrong, for example taking cissus post workout.

Nothing worse than spending good money on supplements just to waste them or cause detrimental effects.
 

mr.cooper69

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The list of contraindications is too massive unfortunately
 
JudgementDay

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I always stay away from mixing is Icariin and Nitrates, also Viagra and Nitrates, it can lower blood pressure too much.

I remember with the old meso formula back in the day had icariin & nitrates, their was enough reports back about feeling dizzy after using the 2 ingredients together.
 
Driven2lift

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The list of contraindications is too massive unfortunately
If we can get the most common mistakes made with mixing I would be happy. I recall a recent post of yours regarding beta alanine but can't find it now
 
booneman77

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Subbed for savings and added efficiency... Good thread idea
 
bigflex0

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I have always dosed T2 products on an empty stomach as that is the way T3 and T4 needs to be dosed. Not sure if there is anything concrete to support this but it makes logical sense.
 
Iain1668

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Has anyone heard of agmatine + d-aspartic acid not to be mixed?

Pretty sure Neuron ( I think) dispelled it.
 
ddfox

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If we can get the most common mistakes made with mixing I would be happy. I recall a recent post of yours regarding beta alanine but can't find it now
Here it is: (From Coop)

"dendrobium alkaloids (namely dendrobine) should not be combined with beta-alanine due to antagonistic reactions/nausea"
 
schizm

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Would you mind enlightening as to why?
Crap, I may have meant tyramine/yohimbe...nattyd had a pretty in depth reason/post as to why, let me see if I can copy/pasta that....sorry guise..
 
alex2678

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Prohormones/Androgens and Coumadin/Bloodthinners. Apparently test increases the potency of the bloodthinners making your blood too thin. I was six days into a prohormone cycle last year when I pulled a hamstring. My blood had gotten so thin that the muscle wouldn't stop bleeding from the inside to the point where my entire leg from glute to ankle was black and blue. Hands down the most painful injury of my life. Required a blood transfusion and 10 days in the hospital. If you ever get prescribed bloodthinners get off your cycle immediately and inform your doc.
 
Diesel0022

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Cissus and Sulbutiamine

They taste too damn bad
 
booneman77

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GMS and water ha
 
mtinsideout

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Subbed for more info, wish I had more to contribute to this but I got nothing at the moment.
 
Synapsin

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Christurner14

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Been wanting a topic made for this for a while I would love to compile a list of ingredients/supplements that should not be mixed either for safety or efficiency reasons. I will kick it off: ARA with anti-inflammatories (cissus, fish oils, etc.) Calcium inhibits the absorption of some minerals such as iron, reduces effectiveness of many sleep aids (ZMa), some antibiotics. Phytic acid (common in foods like oatmeal) will block absorption of many minerals as well, save your multivitamins for later in the day if you enjoy an oatmeal breakfast.
So with the phytic acid, is it right it just blocks some copper, zinc, magnesium and calcium? Or vitamins and other minerals aswell??
 
Driven2lift

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Initial post updated with all additions so far. I will update when I can, I hope we can keep this list going
 
Diesel0022

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Dendrobium alkaloids should not be combined with your supplement consumption due to waste of money reactions.

FTFY

;)

If you happen to be a rat, one specific alkaloid may improve vision

jus saiyan
 
3clipseGT

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The first post should read tyramine and yohimbe as it has what they call a "cheesing effect", not tyrosine and yohimbe.
 
aaronuconn

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Awesome idea for a thread. Keep updating the first post.
 
RecompMan

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Curios to see how long you should wait before taking a Viagra cialis or any other pde5 inhibitor (icariin ect) when using nitrates. When I use Icariin late in the day I feel poor erection quality use to the combo but nothing if I use one or the other
 
tjbruno

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great topic. sub.
 
B5150

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Aside from anecdotal evidence a little substantive supporting data would be greatly appreciated IINTMTA :24:
 

mr.cooper69

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Aside from anecdotal evidence a little substantive supporting data would be greatly appreciated IINTMTA :24:
The FDA released a statement on combining tyrosine + yohimbine, and the dendrobine/BA thing was from a 50+ year old paper that took some major digging :D
 
PharmAnalyst

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I'm sure its common knowledge, but just in case someone missed it: Grapefruit juice, or the P450 enzyme inhibiting substituents of grapefruit, is generally best avoided when taking practically any medicine.
 
drewsicle3210

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I'm sure its common knowledge, but just in case someone missed it: Grapefruit juice, or the P450 enzyme inhibiting substituents of grapefruit, is generally best avoided when taking practically any medicine.
Nobody likes grapefruit anyways. You know?!?
;)
 
PharmAnalyst

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Nobody likes grapefruit anyways. You know?!?
;)
True enough, but it seems like a lot of energy supplements started adding naringin and/or bergamottin at some point to prolong their effects/enhance bio-availability.
 
Sprinterguy4

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I always stay away from mixing is Icariin and Nitrates, also Viagra and Nitrates, it can lower blood pressure too much.

I remember with the old meso formula back in the day had icariin & nitrates, their was enough reports back about feeling dizzy after using the 2 ingredients together.
So Appnut Drive and PES Enhanced is a bad idea?
 

mr.cooper69

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So Appnut Drive and PES Enhanced is a bad idea?
Icariin and nitrates should be fine. Icariin has 1/10th the potency of viagra. The issue with past icariin products is that the majority (yes, the majority, proven by studies) were spiked with clinical PDE5 inhibitors
 
JudgementDay

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So Appnut Drive and PES Enhanced is a bad idea?
I wouldn't myself, when I repped for APS Nutrition had Icariin and Nitrates in Mesomorph, they had enough complaints about customers feeling light headed, so they removed Icariin. That was one of the main reasons why it was taken out of the formula.
 
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51FTY

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I took yohimbe bark and a couple of hours then drank some grapefruit juice. Never threw up so much in my life and just overall felt llike ****.
 
Sprinterguy4

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What about an inhaler along with other beta2 agonists?
 

jamesm11

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Anything to avoid on quetiapine or lorazepam? And no, I'm not crazy.

I'm avoiding nootropics.
 

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