3,3 diiodo-l-thyronine & 3,5 diiodo-l-thyronine

  1. Senior Member
    harbonah's Avatar
    Stats
    6'0"  230 lbs.
    Join Date
    Oct 2009
    Age
    37
    Posts
    1,792
    Rep Power
    283442
    Level
    39
    Lv. Percent
    6.2%
    Achievements Activity ProPosting Pro

    3,3 diiodo-l-thyronine & 3,5 diiodo-l-thyronine


    What is going on with these two supplements I cant seem to find them anywhere and im running low on my stash...did everyone discontinue using these or what? sorry if i missed a post on this already but.
    ForeRunner Labs
    The Future of Human Performance
    http://anabolicminds.com/forum/pics/229429-my-fat-mess.html

  2. Registered User
    swole210's Avatar
    Join Date
    Jul 2005
    Age
    37
    Posts
    1,088
    Rep Power
    660
    Level
    25
    Lv. Percent
    9.43%
    Achievements Posting Pro

    SNS Thyrocaps (3,3) and VPX Thyrovex (3,5)
  3. New Member
    ITW's Avatar
    Stats
    5'11"  185 lbs.
    Join Date
    Jun 2012
    Posts
    437
    Rep Power
    12512
    Level
    17
    Lv. Percent
    78.24%

    How effective are these anyway...?
    •   
       

  4. Diamond Member
    mr.cooper69's Avatar
    Join Date
    Feb 2011
    Posts
    10,539
    Rep Power
    6137603
    Level
    96
    Lv. Percent
    76.69%
    Achievements Activity ProActivity AuthorityActivity VeteranActivity RoyaltyPosting Pro

    If you want a thyrogenic supplement, the new Alpha-T2 has a compound which dramatically ramps up 3'/5'-deiodinase activity in vivo, resulting in more active thyroid hormone and an increased metabolic rate. It is much more effective than diiodothyronines
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
  5. Senior Member
    antihero's Avatar
    Join Date
    Jan 2006
    Posts
    1,357
    Rep Power
    253648
    Level
    33
    Lv. Percent
    72.25%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by harbonah View Post
    What is going on with these two supplements I cant seem to find them anywhere and im running low on my stash...did everyone discontinue using these or what? sorry if i missed a post on this already but.
    Thyrocaps are VERY affordable.
    Serious Nutrition Solutions
    Revolutionizing Sports Nutrition, One Product At A Time
    antihero [@] SeriousNutritionSolutions.com
  6. Advanced Member
    Bamski's Avatar
    Stats
    6'4"  222 lbs.
    Join Date
    Apr 2011
    Posts
    884
    Rep Power
    513835
    Level
    36
    Lv. Percent
    6.3%
    Achievements Activity Pro

    I still have couple of bottles of OG alpha T2 and OG dexaprine I'm sure if you look around you'll be able to find some!
  7. RickyBDragon's Avatar
    Stats
    6'3"  235 lbs.
    Join Date
    Sep 2012
    Age
    31
    Posts
    122
    Rep Power
    0
    Level
    18
    Lv. Percent
    35.95%

    iForce TT-33 is still available and nutraplanet has it at a great price.
  8. Senior Member
    harbonah's Avatar
    Stats
    6'0"  230 lbs.
    Join Date
    Oct 2009
    Age
    37
    Posts
    1,792
    Rep Power
    283442
    Level
    39
    Lv. Percent
    6.2%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by ITW View Post
    How effective are these anyway...?
    I can only say the synergy is there between these and other substances much like T3 maybe not as strong but they work.

    Sent from my A500 using Tapatalk HD
    ForeRunner Labs
    The Future of Human Performance
    http://anabolicminds.com/forum/pics/229429-my-fat-mess.html
  9. Senior Member
    harbonah's Avatar
    Stats
    6'0"  230 lbs.
    Join Date
    Oct 2009
    Age
    37
    Posts
    1,792
    Rep Power
    283442
    Level
    39
    Lv. Percent
    6.2%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by mr.cooper69 View Post
    If you want a thyrogenic supplement, the new Alpha-T2 has a compound which dramatically ramps up 3'/5'-deiodinase activity in vivo, resulting in more active thyroid hormone and an increased metabolic rate. It is much more effective than diiodothyronines
    Any chance you can put up some studies I would enjoy a good read.

    Sent from my A500 using Tapatalk HD
    ForeRunner Labs
    The Future of Human Performance
    http://anabolicminds.com/forum/pics/229429-my-fat-mess.html
  10. Advanced Member
    Bamski's Avatar
    Stats
    6'4"  222 lbs.
    Join Date
    Apr 2011
    Posts
    884
    Rep Power
    513835
    Level
    36
    Lv. Percent
    6.3%
    Achievements Activity Pro

    Quote Originally Posted by harbonah View Post
    Any chance you can put up some studies I would enjoy a good read.

    Sent from my A500 using Tapatalk HD
    use the search button, ive posted quite a few studies on rats as well as human studies but it was a while back!
  11. Senior Member
    harbonah's Avatar
    Stats
    6'0"  230 lbs.
    Join Date
    Oct 2009
    Age
    37
    Posts
    1,792
    Rep Power
    283442
    Level
    39
    Lv. Percent
    6.2%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by Bamski View Post
    use the search button, ive posted quite a few studies on rats as well as human studies but it was a while back!
    What am I searching for I honestly have not looked into the new alpha t-2 so I do not even know what is in it other then noticing a while back it did not have 3,3 diiodo-l-thyronine & 3,5 diiodo-l-thyronine.
    ForeRunner Labs
    The Future of Human Performance
    http://anabolicminds.com/forum/pics/229429-my-fat-mess.html
  12. New Member
    Wocheezy's Avatar
    Stats
    5'9"  230 lbs.
    Join Date
    Apr 2011
    Posts
    185
    Rep Power
    42090
    Level
    14
    Lv. Percent
    91.14%

    http anabolicminds.com/forum/supplements/221327-3-3-3-a(dot)html

    Can't believe I can't post Links yet lol
    Replace (dot)
  13. Senior Member
    harbonah's Avatar
    Stats
    6'0"  230 lbs.
    Join Date
    Oct 2009
    Age
    37
    Posts
    1,792
    Rep Power
    283442
    Level
    39
    Lv. Percent
    6.2%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by Wocheezy View Post
    http anabolicminds.com/forum/supplements/221327-3-3-3-a(dot)html

    Can't believe I can't post Links yet lol
    Replace (dot)
    There is a lot of panic in that thread about T2, I posted the below in response to something on another board but I feel it would also be relevant here.


    "I honestly would not worry about T2. T3 does not seem to even cause an issue I am doubting T2 would 3,3 or 3,5 the below quoted text has made its rounds on the boards and I have personally tested this with my own research up to a year of T3 with virtually no shutdown to my own T3.

    "In 1951, Greer reported the pattern of recovery of thyroid function after stopping suppressive treatment with thyroid hormone in euthyroid [normal] subjects based on sequential measurements of their thyroidal uptake of radioiodine. He observed that after withdrawal of exogenous thyroid therapy, thyroid function, in terms of radioiodine uptake, returned to normal in most subjects within two weeks. He further observed that thyroid function returned as rapidly in those subjects whose glands had been depressed by several years of thyroid medication as it did in those whose gland had been depressed for only a few days" (3) These results have been subsequently verified in several studies. (3)(4) So contrary to what has been stated in the bodybuilding literature, there is no evidence that long term thyroid supplementation will somehow damage your thyroid gland. Greer,M. N Engl J Med 244:385, 1951)"
    ForeRunner Labs
    The Future of Human Performance
    http://anabolicminds.com/forum/pics/229429-my-fat-mess.html
  14. Advanced Member
    Bamski's Avatar
    Stats
    6'4"  222 lbs.
    Join Date
    Apr 2011
    Posts
    884
    Rep Power
    513835
    Level
    36
    Lv. Percent
    6.3%
    Achievements Activity Pro

    Quote Originally Posted by harbonah View Post
    What am I searching for I honestly have not looked into the new alpha t-2 so I do not even know what is in it other then noticing a while back it did not have 3,3 diiodo-l-thyronine & 3,5 diiodo-l-thyronine.
    Oh, are you looking for studies for 3,3 and 3,5 or the new ingredients in the new T2?
  15. Senior Member
    harbonah's Avatar
    Stats
    6'0"  230 lbs.
    Join Date
    Oct 2009
    Age
    37
    Posts
    1,792
    Rep Power
    283442
    Level
    39
    Lv. Percent
    6.2%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by Bamski View Post
    Oh, are you looking for studies for 3,3 and 3,5 or the new ingredients in the new T2?
    The new ingredients for Alpha T2 is what i was referring to I have seen plenty supporting 3,3 and 3,5.
    I remember mr cooper from another board and he was very much study based there so I assume he would have them for the product and company he reps for.
    ForeRunner Labs
    The Future of Human Performance
    http://anabolicminds.com/forum/pics/229429-my-fat-mess.html
  16. Advanced Member
    Bamski's Avatar
    Stats
    6'4"  222 lbs.
    Join Date
    Apr 2011
    Posts
    884
    Rep Power
    513835
    Level
    36
    Lv. Percent
    6.3%
    Achievements Activity Pro

    Ahhhh that clears up the air haha.

    http://www.ergo-log.com/olive-leaf-e...d-hormone.html - Olive Leaf

    http://www.sciencedirect.com/science...7887410200048X - Bacopa

    Should know what ausinystalia Johimbe Bark Extract is... (Yohimbe)

    Norcoclaurine HCl (Higenamine HCl) is basically known as a beta-adrenergic receptor agonist, a mechanism shared by ephedrine and synephrine for their ability to reduce Fat Mass.
  17. Banned
    lronFist's Avatar
    Join Date
    Sep 2012
    Posts
    181
    Rep Power
    0
    Level
    22
    Lv. Percent
    13.12%

    Quote Originally Posted by Bamski View Post
    Norcoclaurine HCl (Higenamine HCl) is basically known as a beta-adrenergic receptor agonist, a mechanism shared by ephedrine and synephrine for their ability to reduce Fat Mass.
    Synephrine is not a beta-adrenergic receptor agonist.

    Higenamine has a 5 minute half life and terrible bioavailability and would have no effect on fat metabolism.
  18. Advanced Member
    Bamski's Avatar
    Stats
    6'4"  222 lbs.
    Join Date
    Apr 2011
    Posts
    884
    Rep Power
    513835
    Level
    36
    Lv. Percent
    6.3%
    Achievements Activity Pro

    Quote Originally Posted by lronFist View Post
    Synephrine is not a beta-adrenergic receptor agonist.

    Higenamine has a 5 minute half life and terrible bioavailability and would have no effect on fat metabolism.
    Thought it hits the beta-3 receptor? even though for humans i know is irrelevant compared to B1/B2 receptors.

    I am going off the list of ingredients on T2, so therefore thats why I included it.
  19. Diamond Member
    mr.cooper69's Avatar
    Join Date
    Feb 2011
    Posts
    10,539
    Rep Power
    6137603
    Level
    96
    Lv. Percent
    76.69%
    Achievements Activity ProActivity AuthorityActivity VeteranActivity RoyaltyPosting Pro

    The study is here: http://www.ncbi.nlm.nih.gov/pubmed/12164280.

    A mere 500 micrograms daily (the dose in Alpha-T2 crushes this) dose-dependently increased active T3 by nearly 300%. T4 also increased by about 25%. Evidently, 3'/5'-deidonase, which is responsible for peripheral conversion of T4 to T3, was upregulated with Olive Leaf Extract supplementation.

    Due to obvious differences between rats and humans, the dose of the extract has been titrated accordingly...but there is also quite a bit of data on the ability of various olive constituents to promote a healthy lipid profile and a mild uncoupling effect in humans.
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
  20. Registered User
    swole210's Avatar
    Join Date
    Jul 2005
    Age
    37
    Posts
    1,088
    Rep Power
    660
    Level
    25
    Lv. Percent
    9.43%
    Achievements Posting Pro

    Quote Originally Posted by mr.cooper69 View Post
    The study is here: http://www.ncbi.nlm.nih.gov/pubmed/12164280.

    A mere 500 micrograms daily (the dose in Alpha-T2 crushes this) dose-dependently increased active T3 by nearly 300%. T4 also increased by about 25%. Evidently, 3'/5'-deidonase, which is responsible for peripheral conversion of T4 to T3, was upregulated with Olive Leaf Extract supplementation.
    Due to obvious differences between rats and humans, the dose of the extract has been titrated accordingly...but there is also quite a bit of data on the ability of various olive constituents to promote a healthy lipid profile and a mild uncoupling effect in humans.
    I've had great success with 3,3 and 3,5 together in the past. I have really fallen out off track in the past few years due to life, lol, and have gotten very...plump. As such, I purchased VPX Thyrovex, SNS Thyrocaps, AND the new Aplpha T-2. I have just started these as a stack a few days ago. I am sweating like a fat man at a buffet so far, but now that I read your posts...should I be staking these products together?
  21. Elite Member
    Jiigzz's Avatar
    Stats
    5'10"  205 lbs.
    Join Date
    Mar 2012
    Posts
    5,385
    Rep Power
    4092216
    Level
    79
    Lv. Percent
    57.03%
    Achievements Activity ProActivity AuthorityActivity VeteranPosting ProPosting Authority

    Quote Originally Posted by harbonah View Post
    There is a lot of panic in that thread about T2, I posted the below in response to something on another board but I feel it would also be relevant here.


    "I honestly would not worry about T2. T3 does not seem to even cause an issue I am doubting T2 would 3,3 or 3,5 the below quoted text has made its rounds on the boards and I have personally tested this with my own research up to a year of T3 with virtually no shutdown to my own T3.

    "In 1951, Greer reported the pattern of recovery of thyroid function after stopping suppressive treatment with thyroid hormone in euthyroid [normal] subjects based on sequential measurements of their thyroidal uptake of radioiodine. He observed that after withdrawal of exogenous thyroid therapy, thyroid function, in terms of radioiodine uptake, returned to normal in most subjects within two weeks. He further observed that thyroid function returned as rapidly in those subjects whose glands had been depressed by several years of thyroid medication as it did in those whose gland had been depressed for only a few days" (3) These results have been subsequently verified in several studies. (3)(4) So contrary to what has been stated in the bodybuilding literature, there is no evidence that long term thyroid supplementation will somehow damage your thyroid gland. Greer,M. N Engl J Med 244:385, 1951)"
    T3 can have a tremendous effect on thyroid output if not dosed appropriately. As a lot of glands operate on a closed loop feedback system meaning that elevated levels of many hormones (including t3) have the capacity to inhibit the output of those very same hormones within the body; there is no point for the body to continually supply TSH if circulating levels of t3 are high already.

    I know this thread isn't about t3, but just clearing that up in case people misinterpret what you wrote.
  22. Diamond Member
    mr.cooper69's Avatar
    Join Date
    Feb 2011
    Posts
    10,539
    Rep Power
    6137603
    Level
    96
    Lv. Percent
    76.69%
    Achievements Activity ProActivity AuthorityActivity VeteranActivity RoyaltyPosting Pro

    Quote Originally Posted by swole210 View Post
    I've had great success with 3,3 and 3,5 together in the past. I have really fallen out off track in the past few years due to life, lol, and have gotten very...plump. As such, I purchased VPX Thyrovex, SNS Thyrocaps, AND the new Aplpha T-2. I have just started these as a stack a few days ago. I am sweating like a fat man at a buffet so far, but now that I read your posts...should I be staking these products together?
    These two may actually be beneficial to stack because the new Alpha-T2 promotes natural thyroid function, which is useful in the face of the slightly suppressive 3,5 diiodothyronine
    http://pescience.com/
    http://selectprotein.com/
    The above is my own opinion and does not reflect the opinion of PES
  23. Professional Member
    VaughnTrue's Avatar
    Join Date
    Jun 2007
    Posts
    3,914
    Rep Power
    1018911
    Level
    55
    Lv. Percent
    87.32%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by mr.cooper69 View Post
    These two may actually be beneficial to stack because the new Alpha-T2 promotes natural thyroid function, which is useful in the face of the slightly suppressive 3,5 diiodothyronine
    pretty awesome benefit of the new Alpha-T2. would go great with some TT-33
  24. New Member
    rtshizzle's Avatar
    Join Date
    Jun 2013
    Posts
    6
    Rep Power
    20
    Level
    2
    Lv. Percent
    29.33%

    so it could be possible to take i-force's tt-33 with alpha-t2
    cause if so that would be awesome
  25. Advanced Member
    thedarce's Avatar
    Stats
    5'7"  179 lbs.
    Join Date
    Nov 2011
    Age
    30
    Posts
    729
    Rep Power
    383098
    Level
    32
    Lv. Percent
    41.66%
    Achievements Activity Pro

    Quote Originally Posted by rtshizzle View Post
    so it could be possible to take i-force's tt-33 with alpha-t2
    cause if so that would be awesome
    looks that way, if only nutra had a stack alpha t2 + tt33 win win!
  26. New Member
    FireRescue's Avatar
    Join Date
    Sep 2008
    Posts
    416
    Rep Power
    29702
    Level
    18
    Lv. Percent
    11.32%

    What it an effective/proper dosing for 3,3 and 3,5?

    Thyrovex has 300mcg of 3,5 and a max of 900mcg/day.
    TT-33 is 100mcg of 3,3 and 50mcg of 3,5 with a max of 400mcg of 3,3/day and 200mcg of 3,5 per day.
    Thyrocaps is 150mcg of 3,3 and a max of 600mcg/day.

    VPX has a much more generous dosing of 3,5 than Iforce, but Im guessing the synergy between the two and potential risk of using both together is the reason Iforce is scaled back some. Same with SNS and the 3,3 as compared to Iforce.

    So looking at these three products what is the best stack of products to produce the most beneficial yield of 3,3 and 3,5?

    Thanks.
  27. Board Sponsor
    Urban Monk's Avatar
    Stats
    6'0"  180 lbs.
    Join Date
    Jul 2007
    Posts
    1,461
    Rep Power
    14385
    Level
    29
    Lv. Percent
    6.54%
    Achievements Posting Pro

    What would be the optimal way to stack the new Alpha T2 and tt-33 together?

    Dosage/cycle length, etc
  28. New Member
    iForce Dave's Avatar
    Stats
    5'10"  235 lbs.
    Join Date
    Nov 2008
    Posts
    477
    Rep Power
    908
    Level
    17
    Lv. Percent
    97.51%

    Quote Originally Posted by Urban Monk View Post
    What would be the optimal way to stack the new Alpha T2 and tt-33 together?

    Dosage/cycle length, etc
    i havent used T2 so I would follow the label for dosing, but as for cycle length, I would say 4-8 weeks tops. 6 weeks would probably be a good length

    TT33 I always ramp up, start at 2-3 and work up to 4-6 per day
    iForce Nutrition Sponsored Athlete
    www.iforcenutrition.com
    facebook.com/iforcedave
  29. Senior Member
    harbonah's Avatar
    Stats
    6'0"  230 lbs.
    Join Date
    Oct 2009
    Age
    37
    Posts
    1,792
    Rep Power
    283442
    Level
    39
    Lv. Percent
    6.2%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by iForce Dave View Post
    i havent used T2 so I would follow the label for dosing, but as for cycle length, I would say 4-8 weeks tops. 6 weeks would probably be a good length

    TT33 I always ramp up, start at 2-3 and work up to 4-6 per day
    I very much doubt if you ran it for 6 months that you would suffer any long term damage to your thyroid.. hell years on T3 is unlikely to cause permanent damage.
    ForeRunner Labs
    The Future of Human Performance
    http://anabolicminds.com/forum/pics/229429-my-fat-mess.html
  30. Elite Member
    fightbackhxc's Avatar
    Stats
    5'11"  200 lbs.
    Join Date
    May 2008
    Posts
    7,445
    Rep Power
    987689
    Level
    63
    Lv. Percent
    15%
    Achievements Activity ProActivity AuthorityPosting ProPosting Authority

    Quote Originally Posted by antihero View Post

    Thyrocaps are VERY affordable.
    And effective
    Serious Nutrition Solutions | Online Representative
    Growth Factor XT-GROW! Need Cycle Support? Check out Liver XT.
    Follow SNS on Facebook for more promos!
  31. Senior Member
    antihero's Avatar
    Join Date
    Jan 2006
    Posts
    1,357
    Rep Power
    253648
    Level
    33
    Lv. Percent
    72.25%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by FireRescue View Post
    What it an effective/proper dosing for 3,3 and 3,5?

    Thyrovex has 300mcg of 3,5 and a max of 900mcg/day.
    TT-33 is 100mcg of 3,3 and 50mcg of 3,5 with a max of 400mcg of 3,3/day and 200mcg of 3,5 per day.
    Thyrocaps is 150mcg of 3,3 and a max of 600mcg/day.

    VPX has a much more generous dosing of 3,5 than Iforce, but Im guessing the synergy between the two and potential risk of using both together is the reason Iforce is scaled back some. Same with SNS and the 3,3 as compared to Iforce.

    So looking at these three products what is the best stack of products to produce the most beneficial yield of 3,3 and 3,5?

    Thanks.
    I think I would go with the Thyrocaps and Thyrovex so that you can independently control the doses of each compound.
    Serious Nutrition Solutions
    Revolutionizing Sports Nutrition, One Product At A Time
    antihero [@] SeriousNutritionSolutions.com
  32. New Member
    FireRescue's Avatar
    Join Date
    Sep 2008
    Posts
    416
    Rep Power
    29702
    Level
    18
    Lv. Percent
    11.32%

    Quote Originally Posted by antihero View Post
    I think I would go with the Thyrocaps and Thyrovex so that you can independently control the doses of each compound.

    That what I'm thinking. However Im still not sure if 600mcg/day of 3,3 and 900mcg/day of 3,5 the proper and effective dosing protocol if running both compounds? I gues that is something I might have to play with.
  33. Senior Member
    antihero's Avatar
    Join Date
    Jan 2006
    Posts
    1,357
    Rep Power
    253648
    Level
    33
    Lv. Percent
    72.25%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by FireRescue View Post

    That what I'm thinking. However Im still not sure if 600mcg/day of 3,3 and 900mcg/day of 3,5 the proper and effective dosing protocol if running both compounds? I gues that is something I might have to play with.
    I recommend starting lower on dosing and working your way up as needed. I believe heavily in the "less is more"approach with these compounds.
    Serious Nutrition Solutions
    Revolutionizing Sports Nutrition, One Product At A Time
    antihero [@] SeriousNutritionSolutions.com
  

  
 

Similar Forum Threads

  1. 3,5-diiodo-l-thyronine presentation
    By holmes215 in forum Supplements
    Replies: 9
    Last Post: 08-24-2011, 03:47 PM
  2. 3,5'-Diiodo-L-Thyronine and aerobic fitness
    By Sevaldrud in forum Supplements
    Replies: 0
    Last Post: 08-17-2011, 02:05 PM
  3. 3,3 and 3,5 Diiodo-L-Thyronine
    By LJ57 in forum Supplements
    Replies: 21
    Last Post: 12-07-2010, 02:44 PM
  4. Bad Sides from Trx (3,5 diiodo-l-thyronine)
    By Brodus in forum Supplements
    Replies: 4
    Last Post: 06-14-2004, 06:20 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in