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    Quote Originally Posted by bdcc View Post

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    You are his boss, right? That Doctor's office must get awfully busy...
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    Quote Originally Posted by bdcc View Post
    You are his boss, right? That Doctor's office must get awfully busy...
    Incredibly busy!
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    Quote Originally Posted by LiveToLift View Post
    Guaranteed! He will be the guy using 3 scoops just for a good buzz before work!
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    For anyone thats interested(like me) here is a good write-up on swertia and its xanthones describing some very brief pharmacological activities, citing very old papers from the 70s and 80s. Turns out this stuff is not very popular outside east Asia.

    scialert(dot)net/fulltext/?doi=crc.2011.1.15&org=12

    I dont have 150 posts so i cannot post references.

    Some highlights:

    For sweroside and gentiopicroside hepatoprotective activities have been reported and both compounds are being used as antihepatitis drugs.
    Xanthones (especially mangiferin) are reported to give CNS stimulation . They should also have anti-inflammatory activity.
    Mangiferin was the first xanthone to be investigated pharmacologically and has been found to exhibit a broad spectrum of biological activities. It shows monoamine oxidase inhibition, cardiotonic, convulsant and choleretic activities.
    Possibly insulin-mimetic or beta adrenergic
    1,8-Dihydroxy-3,5-dimethoxyxanthone (swerchirin), isolated from the hexane fraction of Swertia chirayita, has a very significant blood sugar lowering effect in fasted, fed, glucose loaded and tolbutamide pre-treated albino rats.
    Some xanthones are inhibitory.
    Xanthones of S. chirayita are reported to produce CNS depression.
    And ofc:
    The extract of most of Swertia species showed mutagenic activities.
    I actually read this paper, it was an old japanese study from the 80s testing the mutagenic potential of Swertia xanthones using Ames test. Long story short all xanthones showed mutagenic potential on rat? liver cells. Not to be alarmed though, quercetin is one of the most potent mutagens using the same test. Results have not been replicated in vivo. Besides, several xanthones and quercetin aswell have shown anti-carcinogenic potential.

    Summary:
    The genus Swertia exhibit variety of biological activity such as hepatoprotective, antihepatotoxic, antimicrobial, anti-inflammatory, anticarcinogenic, antileprosy, hypoglycemic, antimalarial, antioxidant, anticholinergic, CNS depressant and mutagenicity.
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