I feel almost silly asking this question, considering that people normally use this supplement as a daily antioxidant. However, since there is some evidence that it significantly increases thyroid hormones, I'm wondering if this product should be cycled like any other product that works on the thyroid (ie. 3,3 and 3,5 based products). I am currently taking a 500mg of a 20% Olereupin(sp?) extract three times per day.