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    Im have bulk cissus powder that ive been using for an injury. Ive read that cissus is anabolic in bone. Im wondering if there is any possible way it would increase jaw size be it the bone mass or the muscles surrounding the jaw?

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    I don't know the answer, but I'm gonna go with a big no...
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    It's not human growth hormone.

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    Quote Originally Posted by oakmuscle View Post
    Im have bulk cissus powder that ive been using for an injury. Ive read that cissus is anabolic in bone. Im wondering if there is any possible way it would increase jaw size be it the bone mass or the muscles surrounding the jaw?
    Probably not. Some of the natural chemical components in Cissus quadrangularis are pentacyclic triterpenes; from what I have seen, they are related (at least structurally) to ursolic acid and bredemolic acid (bredemolic can be made from maslinic acid). Most of the SAR research I have looked at involves the ability of these components to suppresse NFK-β (stress pathway) and inhibit glycogen phosphorylase (allostearic inhibition). They may also work through NO/cGMP pathway (all triterpenes do this), and they may be anabolic through the suppression of bone loss via inhibiting NFK-β.....
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    Quote Originally Posted by rms80 View Post
    Probably not. Some of the natural chemical components in Cissus quadrangularis are pentacyclic triterpenes; from what I have seen, they are related (at least structurally) to ursolic acid and bredemolic acid (bredemolic can be made from maslinic acid). Most of the SAR research I have looked at involves the ability of these components to suppresse NFK-β (stress pathway) and inhibit glycogen phosphorylase (allostearic inhibition). They may also work through NO/cGMP pathway (all triterpenes do this), and they may be anabolic through the suppression of bone loss via inhibiting NFK-β.....
    Id be lying if I said I understood this lol.
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    This question was already asked and answer, both in this thread and on another forum: Cissus Help
    http://pescience.com/
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    The above is my own opinion and does not reflect the opinion of PES
  

  
 

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