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reduce xt ingredients

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    reduce xt ingredients


    7-alpha-hydroxy-dehydoepiandrosterone **
    7-beta-hydroxy-dehydoepiandrosterone

    thinking of trying these two

    how are these different from 7-keto-dhea?

    I know what 7 keto dhea 300 mgs treats me well. Would I need 300 mgs of this stuff since its only 50 mgs a capsule or is this stuff more potent than 7-keto dhea?

    I have to give credit where credit is due I did my first transdermal of protcolnutritions 7 -spray for a month in pct and that is by far my favorite cortisol product to date. I have tried lean xtreme as well so i am guessing this will the same?
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    Quote Originally Posted by John Smeton
    7-alpha-hydroxy-dehydoepiandrosterone **
    7-beta-hydroxy-dehydoepiandrosterone

    thinking of trying these two

    how are these different from 7-keto-dhea?

    I know what 7 keto dhea 300 mgs treats me well. Would I need 300 mgs of this stuff since its only 50 mgs a capsule or is this stuff more potent than 7-keto dhea?

    I have to give credit where credit is due I did my first transdermal of protcolnutritions 7 -spray for a month in pct and that is by far my favorite cortisol product to date. I have tried lean xtreme as well so i am guessing this will the same?
    Reduce xt is the same as the OG Lean xtreme. I suggest dosing at 3 caps per day(150 mgs)
    Do you have any issues with sore joints from lowering cortisol levels?

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    Quote Originally Posted by mw1 View Post
    Reduce xt is the same as the OG Lean xtreme. I suggest dosing at 3 caps per day(150 mgs)
    Do you have any issues with sore joints from lowering cortisol levels?
    that whole cortisol and sore joints is a myth and totally incorrect. In fact these ingredients help with your joints
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    Quote Originally Posted by John Smeton

    that whole cortisol and sore joints is a myth and totally incorrect. In fact these ingredients help with your joints
    Huh? Then you havent used a truly "effective" cortisol product because a (sudden) drop in cortisol levels will cause sore joints

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    I like 2 caps in the AM, one at mid day and one before bed. Very effective.
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    Quote Originally Posted by John Smeton View Post
    7-alpha-hydroxy-dehydoepiandrosterone **
    7-beta-hydroxy-dehydoepiandrosterone

    thinking of trying these two

    how are these different from 7-keto-dhea?

    I know what 7 keto dhea 300 mgs treats me well. Would I need 300 mgs of this stuff since its only 50 mgs a capsule or is this stuff more potent than 7-keto dhea?

    I have to give credit where credit is due I did my first transdermal of protcolnutritions 7 -spray for a month in pct and that is by far my favorite cortisol product to date. I have tried lean xtreme as well so i am guessing this will the same?



    7-oxo is the precursor to 7-OH so this up a step in the conversion and require a smaller dose.
    plus Cissus Quadrangularis do not suppress Cortisol, but rather block cortisol receptors.

    if you wish can try it Cissus XT too
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    Quote Originally Posted by mw1 View Post
    Huh? Then you havent used a truly "effective" cortisol product because a (sudden) drop in cortisol levels will cause sore joints
    i find myself having to take something like cissus and fish oil with cortisol control.
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    Quote Originally Posted by mw1 View Post
    Reduce xt is the same as the OG Lean xtreme. I suggest dosing at 3 caps per day(150 mgs)
    Do you have any issues with sore joints from lowering cortisol levels?
    And the OG was the best!
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    Quote Originally Posted by mw1 View Post
    Huh? Then you havent used a truly "effective" cortisol product because a (sudden) drop in cortisol levels will cause sore joints
    I have used plenty as I have been using bodybuilding supplements for over ten years and studied them(and been large and in charge ten years now, there is some healthy ego =) ). If you read my posts above you see that I have use cortisol controlsupplements

    Its all a big myth and I dont know how that rumor got started, Im supecting someone that misunderstood something. I used to believe it myself until Patrick Arnold convinced me that it actually good for joints. and I know of anyone that is not goodfas Patrick at his work and specifically at 7 keto and 7 keto derivatives

    maybe I need to ask him to come in here and give his opinion on this. I agree with Pat that a truly effective cortisol product is good for the joints

    now ps is neutral because it prevents cortisol from going high and does nothing to reduce it, something that reduces cortisol most likely helps the joints out
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    Quote Originally Posted by John Smeton View Post
    I have used plenty as I have been using bodybuilding supplements for over ten years and studied them(and been large and in charge ten years now, there is some healthy ego =) ). If you read my posts above you see that I have use cortisol controlsupplementsIts all a big myth and I dont know how that rumor got started, Im supecting someone that misunderstood something. I used to believe it myself until Patrick Arnold convinced me that it actually good for joints. and I know of anyone that is not goodfas Patrick at his work and specifically at 7 keto and 7 keto derivativesmaybe I need to ask him to come in here and give his opinion on this. I agree with Pat that a truly effective cortisol product is good for the jointsnow ps is neutral because it prevents cortisol from going high and does nothing to reduce it, something that reduces cortisol most likely helps the joints out
    This is a pretty broad spectrum statement. I don't think that's how PA put it initially. Perhaps he was referring to the MOA of 7-keto, rather than glucocorticoids?
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    Ill ask him to give his opinion on these two, in this thread
    7-alpha-hydroxy-dehydoepiandrosterone **
    7-beta-hydroxy-dehydoepiandrosterone
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    Quote Originally Posted by John Smeton View Post
    I have used plenty as I have been using bodybuilding supplements for over ten years and studied them(and been large and in charge ten years now, there is some healthy ego =) ). If you read my posts above you see that I have use cortisol control supplements
    10 years???? you could have fooled me.
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    Quote Originally Posted by John Smeton View Post
    I have used plenty as I have been using bodybuilding supplements for over ten years and studied them(and been large and in charge ten years now, there is some healthy ego =) ). If you read my posts above you see that I have use cortisol controlsupplements
    And you've been sh!tting your whole life, but can you explain the progression of nervous system activity leading to defecation? Experience means nothing in the context of this discussion. PA knows very well how cortisol behaves in the body. His statement was most likely in regards to 7-keto, which doesn't quite work in the manner that many people assume.
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    Are you sure he wasn't talking about 7 spray not lowering cortisol systemically?
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    Quote Originally Posted by mw1 View Post
    Reduce xt is the same as the OG Lean xtreme. I suggest dosing at 3 caps per day(150 mgs)
    Do you have any issues with sore joints from lowering cortisol levels?

    that compound will not affect circulating cortisol. in fact it will act as an anti-inflammatory itself,

    the whole thing about 7-oxygenated dhea derivatives is misinformation.
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    Quote Originally Posted by mw1 View Post
    Huh? Then you havent used a truly "effective" cortisol product because a (sudden) drop in cortisol levels will cause sore joints

    what ingredient out there will cause a sudden drop in cortisol levels?
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    Quote Originally Posted by MAxximal View Post
    7-oxo is the precursor to 7-OH so this up a step in the conversion and require a smaller dose.
    plus Cissus Quadrangularis do not suppress Cortisol, but rather block cortisol receptors.
    where is the evidence that cissus blocks cortisol receptors?

    maybe there is evidence that it can be antagonist to some of the effects of cortisol (such as in bone) but that does not mean it has any influence on cortisol levels and/or cortisol receptor binding
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    Quote Originally Posted by mr.cooper69 View Post
    PA knows very well how cortisol behaves in the body. His statement was most likely in regards to 7-keto, which doesn't quite work in the manner that many people assume.
    Quote Originally Posted by Patrick Arnold View Post
    the whole thing about 7-oxygenated dhea derivatives is misinformation.
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    The above is my own opinion and does not reflect the opinion of PES
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    Quote Originally Posted by Patrick Arnold View Post
    where is the evidence that cissus blocks cortisol receptors?

    maybe there is evidence that it can be antagonist to some of the effects of cortisol (such as in bone) but that does not mean it has any influence on cortisol levels and/or cortisol receptor binding
    It is indeed a glucocorticoid receptor antagonist in bone tissue.
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    Brb getting some popcorn. And some reduce xt cuz this is gonna get stressful.
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    Quote Originally Posted by mr.cooper69 View Post
    It is indeed a glucocorticoid receptor antagonist in bone tissue.

    since cissus is a plant i find this very interesting (considering no one even knows what the active compounds in cissus actually are).

    Is this something validated by an actual experiment or some mechanism proposed by some Indian scientists to explain the effect on bone but never actually validated
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    Quote Originally Posted by Patrick Arnold

    what ingredient out there will cause a sudden drop in cortisol levels?
    The current version of Lean xtreme. Now your interpretation of sudden drop may differ from mine. I was speaking in regards to a 7-9 time frame...not a 24 hr if you thiught thats what i meant

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    Quote Originally Posted by Patrick Arnold View Post
    since cissus is a plant i find this very interesting (considering no one even knows what the active compounds in cissus actually are). Is this something validated by an actual experiment or some mechanism proposed by some Indian scientists to explain the effect on bone but never actually validated
    The indian scientists told me so . Unfortunately, I read this paper a few years ago and can no longer access it:"Effect of Cissus Quadrangularis on the healing of cortisone treated fractures"No, there are no in vitro assays done.
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    Quote Originally Posted by mr.cooper69 View Post
    The indian scientists told me so . Unfortunately, I read this paper a few years ago and can no longer access it:"Effect of Cissus Quadrangularis on the healing of cortisone treated fractures"No, there are no in vitro assays done.

    I wouldnt quote that paper as any sort of proof for cortisol receptor antagonism
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    Quote Originally Posted by mw1 View Post
    The current version of Lean xtreme. Now your interpretation of sudden drop may differ from mine. I was speaking in regards to a 7-9 time frame...not a 24 hr if you thiught thats what i meant
    Green Tea Extract (50% EGCG), Coleus Forskohlii (40% Forskolin), Phosphatidylserine 45%, 5-AT (5-Etioallocholen-3b,7b,17b-tiol), 7OH (3b,7b-dihydroxy-5-Etioallocholen-17-one)


    The only thing in here that i can see affecting cortisol levels is the PS, and that would simply be to blunt the stress induced increase in cortisol

    green tea - no

    coleus foreskin - no

    the two dhea metabolites - no
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    the two dhea metabolites may be able to lower cortisol levels in target tissues expressing 11b-hsd1 reductase, but that is not the same as in the blood. And connective tissue would not be one of those target tissues. So any sore joints from a product like that would be in your head or due to something other than those ingredients
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    Quote Originally Posted by Patrick Arnold View Post
    since cissus is a plant i find this very interesting (considering no one even knows what the active compounds in cissus actually are).

    Is this something validated by an actual experiment or some mechanism proposed by some Indian scientists to explain the effect on bone but never actually validated
    Bio-activity guided isolation of the methanolic extract of the stems of Cissus quadrangularis Linn., resulted three known compounds

    1. lupeol
    2. freidalin
    3. b-sitosterol
    Attached Images Attached Images
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    Quote Originally Posted by Uziel View Post
    Bio-activity guided isolation of the methanolic extract of the stems of Cissus quadrangularis Linn., resulted three known compounds

    1. lupeol
    2. freidalin
    3. b-sitosterol

    there is no suggestion or indication that any of these compounds are responsible for the anti-inflammatory or other traditionally reported benefits of cissus.

    cissus undoubtedly contains dozens if not hundreds of other compounds in concentrations high enough to be detected using current technology
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    Quote Originally Posted by Patrick Arnold View Post
    there is no suggestion or indication that any of these compounds are responsible for the anti-inflammatory or other traditionally reported benefits of cissus. cissus undoubtedly contains dozens if not hundreds of other compounds in concentrations high enough to be detected using current technology
    Some of its beneficial effects on bones have been elucidated with confidence (i.e. osteogenic stimulation).
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    Quote Originally Posted by Patrick Arnold

    Green Tea Extract (50% EGCG), Coleus Forskohlii (40% Forskolin), Phosphatidylserine 45%, 5-AT (5-Etioallocholen-3b,7b,17b-tiol), 7OH (3b,7b-dihydroxy-5-Etioallocholen-17-one)

    The only thing in here that i can see affecting cortisol levels is the PS, and that would simply be to blunt the stress induced increase in cortisol

    green tea - no

    coleus foreskin - no

    the two dhea metabolites - no
    Perhaps it was the original formula i had used because I'm sure it did not have forskolin in it at the time...either that or myself and the MANY other people that have experienced sore joints from LX just imagined the sore joints i guess . Yea right..i guess now is the time you come in a promote your own product PA

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    Quote Originally Posted by mw1 View Post
    Perhaps it was the original formula i had used because I'm sure it did not have forskolin in it at the time...either that or myself and the MANY other people that have experienced sore joints from LX just imagined the sore joints i guess . Yea right..i guess now is the time you come in a promote your own product PA

    No one is here to promote a product , since you brought it up though the 7 spray was the best I have used thus far, I recommend you try it.

    I am thinking of trying reduce xt.

    Someone brought up that reduce xt lowers cortisol and effects joints,earlier in the thread and I had no idea they would and I am glad you did! Hope this changes your perspective on this topic I see get thrown around all the time , people blindly believing stuff that is just false

    good day everyone
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    Quote Originally Posted by mr.cooper69 View Post
    Some of its beneficial effects on bones have been elucidated with confidence (i.e. osteogenic stimulation).
    Yes that much appears to be true.
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    Quote Originally Posted by mw1 View Post
    Perhaps it was the original formula i had used because I'm sure it did not have forskolin in it at the time...either that or myself and the MANY other people that have experienced sore joints from LX just imagined the sore joints i guess . Yea right..i guess now is the time you come in a promote your own product PA
    I was called in here to discuss science. It is not my intention, let alone my style, to interject in threads to promote my products. People know me and my products as is anyway
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    I thoroughly enjoyed Reduce XT while cutting.

    Didn't experience any joint pain really while on it, but then again I only experienced mild joint pain @ 100mg of Erase so go figure.
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