Androsta-3,5-Diene-7,17-Dione (PES Erase) blood work? - AnabolicMinds.com

Androsta-3,5-Diene-7,17-Dione (PES Erase) blood work?

  1. New Member
    reterded's Avatar
    Join Date
    Dec 2010
    Posts
    4
    Rep Power
    48

    Reputation

    Androsta-3,5-Diene-7,17-Dione (PES Erase) blood work?


    i couldn't find any blood test results anywhere on google. anecdotal reviews say it's very good, perhaps even too strong, and i have used it myself with noticable estrogen reduction. but before i invest further into the product to replace exemestane i'd really like to see some blood work, to see how much it lowers estrogen and how it affects testosterone.

  2. Senior Member
    uvawahoowa's Avatar
    Stats
    6'2"  190 lbs.
    Join Date
    May 2012
    Posts
    1,482
    Rep Power
    31240

    Reputation

    Quote Originally Posted by reterded
    i couldn't find any blood test results anywhere on google. anecdotal reviews say it's very good, perhaps even too strong, and i have used it myself with noticable estrogen reduction. but before i invest further into the product to replace exemestane i'd really like to see some blood work, to see how much it lowers estrogen and how it affects testosterone.
    Triazole has bloodwork to back it up if you want to go that route
  3. New Member
    zaire2d's Avatar
    Join Date
    Apr 2009
    Posts
    91
    Rep Power
    18919

    Reputation

    Erase to replace exemestane? I don't think we even know how exactly androsta-3,5-diene-7,17-dione works inhibiting aromatase to change a proven chemical for it, I mean if you are using exemestane you probably need a strong AI right?
    •   
       

  4. Elite Member
    TheSwanks's Avatar
    Stats
    5'10"  230 lbs.
    Join Date
    Feb 2012
    Age
    30
    Posts
    8,981
    Rep Power
    7167087

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    in for answers
    Formutech Nutrition Rep----------------Check out my CONQU3R log!:
    www.formutechnutrition.com------------- http://goo.gl/G8a4Ss
    www.facebook.com/fnutrition
  5. Advanced Member
    Daycrawler's Avatar
    Stats
    6'1"  200 lbs.
    Join Date
    Apr 2011
    Posts
    825
    Rep Power
    227806

    Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by reterded
    i couldn't find any blood test results anywhere on google. anecdotal reviews say it's very good, perhaps even too strong, and i have used it myself with noticable estrogen reduction. but before i invest further into the product to replace exemestane i'd really like to see some blood work, to see how much it lowers estrogen and how it affects testosterone.
    Later this year I'll be running Erase with pre and post bloodwork. It is by far my favorite compound and hopefully bloodwork will qualm some concerns.
  6. Elite Member
    andrew732's Avatar
    Join Date
    Jun 2008
    Posts
    5,458
    Rep Power
    489926

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Actually appnut did bloodwork for Freetest which uses the same Ai.
    doing my own thang!
  7. Senior Member
    Clemenza's Avatar
    Stats
    5'11"  205 lbs.
    Join Date
    Jan 2011
    Posts
    1,412
    Rep Power
    557664

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    I forgot if it was this forum or another but I saw recently someone post that they did bloods using Erase Pro and had a significant reduction is Estradiol.

    Either way the stuff works.
    PES ALPHAMINE Log
    h ttp://anabolicminds.com/forum/supplement-reviews-logs/213082-pes-alphamine-log.html
  8. Senior Member
    lboston's Avatar
    Stats
    5'7"  195 lbs.
    Join Date
    Oct 2011
    Age
    29
    Posts
    1,244
    Rep Power
    27136

    Reputation

    Quote Originally Posted by Clemenza
    I forgot if it was this forum or another but I saw recently someone post that they did bloods using Erase Pro and had a significant reduction is Estradiol.

    Either way the stuff works.
    I had t pellets put in for TRT and estrodial ship up to around 47 (maybe a tad more). Did erase at 2 caps a day for nearly 3 or so weeks and estrodiol was down to 11 ( don't recall the exact unit name; I think pg/nl.

    My have been that my T levels falling over the course of two months on the pellets/ but I certainly believe erase had something to do with it.
  9. Professional Member
    tnubs's Avatar
    Stats
    5'8"  220 lbs.
    Join Date
    Mar 2008
    Posts
    3,248
    Rep Power
    23617

    Reputation

    Quote Originally Posted by reterded View Post
    i couldn't find any blood test results anywhere on google. anecdotal reviews say it's very good, perhaps even too strong, and i have used it myself with noticable estrogen reduction. but before i invest further into the product to replace exemestane i'd really like to see some blood work, to see how much it lowers estrogen and how it affects testosterone.
    do you have exemestane on hand? i havnt gotten bloods on either but they both do the job very well for me
    CELTIC LABS REP
  10. New Member
    reterded's Avatar
    Join Date
    Dec 2010
    Posts
    4
    Rep Power
    48

    Reputation

    Quote Originally Posted by zaire2d View Post
    Erase to replace exemestane? I don't think we even know how exactly androsta-3,5-diene-7,17-dione works inhibiting aromatase to change a proven chemical for it, I mean if you are using exemestane you probably need a strong AI right?
    yes i need a strong AI. i'm looking into androsta-3,5-diene-7,17-dione mostly for legal reasons. with exemestane i risk getting into trouble if customs intercept my packages and/or if my house gets raided. i have to order it from overseas because exemestane from the black market within my country is too expensive. exemestane is the only illegal thing i own besides DNP, and having DNP is less serious of a crime.

    nattydisaster obviously has a vested interest, but if what he says is true then it sounds like androsta-3,5-diene-7,17-dione could be quite good:

    Quote Originally Posted by nattydisaster View Post
    People have gotten bloods...search for them. Would you rather us give out company released bloodwork? lol

    The reviews are so beyond this forum. They are on all the major forums, forums we dont sponsor, even forums we arent allowed to post on. There is reviews at the brick and mortar level, international level, languages i dont even speak, etc.

    It works...if you dont think it works then thats cool too.

    We didnt go find a study that referenced an aromatase inhibitor and then stick it in a pill. We researched the ingredient, we saw its extremely potent AI abilities, Ki of 0.22!

    But we knew this wasnt the end of the story...look at things like chrysin that have great data with horrible real world feedback.

    We started looking at the structure and saw that the androst-backbone is extremely popular for aromatase inhibitors (6-bromo, 6-oxo, ATD, aromasin, formestane) and that 3-enes and 3,5-dienes consistently showed strong AI abilities.

    Still not the end of the story....we knew we had to test it.

    We sourced it and started testing doses based on other similar compounds and theoretical bioavailability and Ki values. We started dosing low and worked up to 150mg.

    All of our testers had previous AI experience, including Rx AI's. Everyone noticed that after 100mg it was too strong. We scaled the doses back, cycled on and off, and discovered the best dose was 50-75mg which is why the capsules are 25mg each, and Erase Pro is 75mg.

    I have never believed in company released bloodwork. To me, it makes it look like the product is trying too hard. Erase sells itself...because it works. Thats what I stand by, products that work.
    i'm not great with chemistry but the IUPAC name for exemestane (6-Methylideneandrosta-1,4-diene-3,17-dione) does seem to have its resemblances to androsta-3,5-diene-7,17-dione.

    exemestane is brilliant for bodybuilding in that it lowers estrogen, raises testosterone and has an androgenic metabolite that boosts muscle growth and fat loss. but androsta-3,5-diene-7,17-dione is said to have a powerful cortisol-reducing effect so maybe it's not bad at all compared to exemestane.

    Quote Originally Posted by andrew732 View Post
    Actually appnut did bloodwork for Freetest which uses the same Ai.
    is 3,7-Keto DHEA just another name for androsta-3,5-diene-7,17-dione? i like those results, the product has more ingredients in it but a 49% increase in total test and a 78% increase in free test is pretty good. it doesn't seem to be quite as good at boosting testosterone as exemestane, but AppNut Free Test has 3,7-Keto listed in a proprietary blend so who knows what dose they used.

    The 25- and 50-mg doses of daily exemestane had comparable effects in suppressing circulating estrogen concentrations, with 38 24% (mean SD; P = 0.002 vs. baseline) and 32 29% (P = 0.008) decreases in estradiol concentrations, 71 12% (P < 0.0001) and 74 12% (P < 0.0001) decreases in estrone concentrations, and 45 27% (P = 0.004) and 51 20% (P = 0.02) decreases in estrone sulfate concentrations after doses of 25 and 50 mg, respectively. There was an increase in circulating testosterone concentrations after both 25 mg (60 58%; P = 0.001) and 50 mg (56 48%; P = 0.003) exemestane. Androstenedione concentrations were increased as well after 25 mg (32 36%; P = 0.004) and 50 mg (47 59%; P = 0.052) exemestane, respectively (Fig. 1⇓ and Table 2⇓). SHBG concentrations were decreased by 21 7% (P = 0.0003) and 19 39% (P = 0.18) at 25 and 50 mg exemestane, respectively. Free testosterone concentrations were increased by 117 74% (P = 0.0001) and 154 95% (P < 0.0001) at both doses, due to the decrease in SHBG and the increase in total testosterone.
    Quote Originally Posted by tnubs View Post
    do you have exemestane on hand? i havnt gotten bloods on either but they both do the job very well for me
    i have 100+ doses of 25 mg exemestane on hand. there is a domestic brand that has basically a cheaper PES Erase clone that sells out very quickly. when it comes back into stock next week i might buy 100 doses of 75 mg androsta-3,5-diene-7,17-dione for the equivalent of $100 to use when i run out of exemestane. it seems like 75 mg androsta-3,5-diene-7,17-dione could be at least as good as 25 mg exemestane, a fair amount of people complain about joint pains at 75 mg and i found a thread on here where Jasen was on a gram of test and his estrogen stayed within range.
  11. Professional Member
    kevinhy's Avatar
    Stats
    5'10"  210 lbs.
    Join Date
    Jul 2009
    Posts
    3,138
    Rep Power
    291860

    Reputation Reputation Reputation Reputation Reputation Reputation

    There are lots of forum users who have gotten bloods while on Erase and noted a significant reduction. lboston, your results sound very good!
    PES - PM me anytime for any questions
    "Like" us on Facebook
    Subscribe to the PES Newsletter for all Specials and Announcements
  12. Elite Member
    TheSwanks's Avatar
    Stats
    5'10"  230 lbs.
    Join Date
    Feb 2012
    Age
    30
    Posts
    8,981
    Rep Power
    7167087

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by kevinhy View Post
    There are lots of forum users who have gotten bloods while on Erase and noted a significant reduction. lboston, your results sound very good!
    You don't by any chance have any links do you, Kevin? I love Erase and EP, but I've very curious to see what the real physiological effect of the ingredient really is.
    Formutech Nutrition Rep----------------Check out my CONQU3R log!:
    www.formutechnutrition.com------------- http://goo.gl/G8a4Ss
    www.facebook.com/fnutrition
  13. Professional Member
    kevinhy's Avatar
    Stats
    5'10"  210 lbs.
    Join Date
    Jul 2009
    Posts
    3,138
    Rep Power
    291860

    Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by cswalczakny View Post
    You don't by any chance have any links do you, Kevin? I love Erase and EP, but I've very curious to see what the real physiological effect of the ingredient really is.
    The main one that comes to mind is an AM member running 1000mg testosterone, and using Erase at 3 caps solely for estrogen control. His Estradiol levels were at 31, which is ridiculous considering the amount of test he was on.

    Iron Liver is getting his bllods draws, interesting INFO INside, PLS COME ON IN.
    PES - PM me anytime for any questions
    "Like" us on Facebook
    Subscribe to the PES Newsletter for all Specials and Announcements
  14. Elite Member
    TheSwanks's Avatar
    Stats
    5'10"  230 lbs.
    Join Date
    Feb 2012
    Age
    30
    Posts
    8,981
    Rep Power
    7167087

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by kevinhy View Post
    The main one that comes to mind is an AM member running 1000mg testosterone, and using Erase at 3 caps solely for estrogen control. His Estradiol levels were at 31, which is ridiculous considering the amount of test he was on.

    Iron Liver is getting his bllods draws, interesting INFO INside, PLS COME ON IN.
    serum test @ 1500 and E2 @ 31, nice ratio
    Formutech Nutrition Rep----------------Check out my CONQU3R log!:
    www.formutechnutrition.com------------- http://goo.gl/G8a4Ss
    www.facebook.com/fnutrition
  15. Professional Member
    kevinhy's Avatar
    Stats
    5'10"  210 lbs.
    Join Date
    Jul 2009
    Posts
    3,138
    Rep Power
    291860

    Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by cswalczakny View Post
    serum test @ 1500 and E2 @ 31, nice ratio
    serum test >1500!
    PES - PM me anytime for any questions
    "Like" us on Facebook
    Subscribe to the PES Newsletter for all Specials and Announcements
  16. Elite Member
    TheSwanks's Avatar
    Stats
    5'10"  230 lbs.
    Join Date
    Feb 2012
    Age
    30
    Posts
    8,981
    Rep Power
    7167087

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by kevinhy View Post
    serum test >1500!
    oh sh*t you're right. lol, idk how I missed that. even better!
    Formutech Nutrition Rep----------------Check out my CONQU3R log!:
    www.formutechnutrition.com------------- http://goo.gl/G8a4Ss
    www.facebook.com/fnutrition
  17. Senior Member
    Clemenza's Avatar
    Stats
    5'11"  205 lbs.
    Join Date
    Jan 2011
    Posts
    1,412
    Rep Power
    557664

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by kevinhy View Post
    The main one that comes to mind is an AM member running 1000mg testosterone, and using Erase at 3 caps solely for estrogen control. His Estradiol levels were at 31, which is ridiculous considering the amount of test he was on.

    Iron Liver is getting his bllods draws, interesting INFO INside, PLS COME ON IN.
    WOW! Pretty legit!
    PES ALPHAMINE Log
    h ttp://anabolicminds.com/forum/supplement-reviews-logs/213082-pes-alphamine-log.html
  •   

      
     

Similar Forum Threads

  1. PES Erase blood works
    By Superpippo in forum PES
    Replies: 28
    Last Post: 05-12-2011, 09:34 AM
  2. T-Roid (19-Norandrosta-4,9-diene-3,17-dione)
    By GeneraSupps in forum Company Promotions
    Replies: 56
    Last Post: 05-03-2009, 01:14 AM
  3. Estra-4,9-diene-3,17-dione ?
    By lennoxchi in forum Anabolics
    Replies: 20
    Last Post: 12-11-2008, 05:27 PM
  4. Replies: 8
    Last Post: 04-07-2008, 01:33 AM
  5. Replies: 4
    Last Post: 04-06-2008, 05:30 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in