- 06-04-2012, 01:59 PM
- 06-04-2012, 02:03 PM
My doctoral dissertation is investigating the effects of betaine on strength, power, and body composition in trained men. I can tell you just about anything you'd like to know about betaine with the exception of the outcome of the study (its still going on) about betaine.
06-04-2012, 02:06 PM
06-04-2012, 02:12 PM
06-04-2012, 02:16 PM
06-04-2012, 02:19 PM
Results from animal studies, especially in pigs, shows fantastic results: increased lean mass, decreased fat mass, improved nutrient partitioning, down regulation in lipogenic enzymes/genes, upregulation of some anabolic enzymes, increased insulin and IGF1 signalling, and increased GH secretion.
There is also one human study that shows betaine increases GH...I'm not sure if it is published yet though.
06-04-2012, 02:32 PM
06-04-2012, 02:32 PM
06-04-2012, 02:44 PM
2.5 g per day for 6 weeks. Training is standardized, and is an NLP hypertrophy based program. Other sport supplements are prohibited. Diet isn't standardized, but all subjects have been given nutrition counseling based on 3 day dietary logs to ensure adequate protein and caloric intake.
06-04-2012, 02:51 PM
06-04-2012, 02:55 PM
"The only good is knowledge and the only evil is ignorance." - Socrates
06-04-2012, 03:29 PM
06-04-2012, 03:31 PM
06-04-2012, 03:35 PM
06-04-2012, 03:58 PM
"Jackie Treehorn treats objects like woman man."
06-04-2012, 04:25 PM
Ty.. Proper dosing is half the battle.. So 1grm morning and 1grams evening.? Would this be sufficient or 2 grms morning 1 gray evening to ensure proper quantity? In your opinion?
Droid razor maxx
06-04-2012, 04:37 PM
Good question. One that I really can't answer absolutely at this time.
All the research studies have been done at around 2 to 2.5 grams. In pigs, the equated amount was about 3g per day in a 50 kg animal...so, you could always go with 3g per day. The side effects, which at this time are known to be GI distress, really don't set in until around 10g per day, and none were reported in clinical subjects using around 5g per day. So, if cost is not an issue, I don't see a problem with it.
06-04-2012, 04:40 PM
Combo of Betaine/Agmatine/DAA and ERase Pro was killer andsurprised the hell out of me...
Add some creatine in the Mix, you have a very affordablestack that is surprisingly effective.
06-04-2012, 04:42 PM
I find it fairly cheap I use now sports tmg think ill start dosing 4 grms a day 2 morning and 2 evening.. See how that works thanks for all your help ill rep you when I get on my lap top! Cheers
Droid razor maxx
06-04-2012, 06:17 PM
Is tmg a specific form of betaine or would any betaine supp be the same?Originally Posted by texasfinest2
06-04-2012, 06:26 PM
n-n-n-methyl-glycine (TMG) is the chemical name for betaine. TMG was discovered in the late 1800's in sugar beets and named betaine.
06-04-2012, 08:04 PM
06-04-2012, 08:38 PM
Is it true that betaine helps your body produce its own source of creatineOriginally Posted by ZiR RED
06-05-2012, 08:49 AM
In simple terms, it goes like this:
Guanidinoacetate is formed in the kidneys form glycine and arginine. GAA is then transported to the liver, where it is methylated (a methyl group is removed from S-adenosylmethionine (SAM) )to form creatine. The creatine is then released into the blood and taken up by muscles.
Betaine contains 3 methyl groups (hence the n-n-n-glycine). In methylation metabolism, betaine donates a methyl group (becoming dimethylglycine: DMG) to methionine forming SAM.
So, by increasing SAM it was thought that betaine may improve creatine biosynthesis leading to additional creatine in the muscles. This was true in animals; however, in a recent study it was found not to happen in humans. Now, these humans were untrained and not given an exercise program, so additional creatine synthesis may not have been needed. It would be interesting to see if betaine improves creatine in athletes who train using the CP system (i.e.: heavy weight training, short sprints with full recovery).
That said, increasing methylation potential may improve hypertrophy and strength in a number of other ways that I mentioned as benefits to betaine.
EDIT: I just emailed the author of the study cited above to ask his thoughts on the hypothesis that because creatine demand and storage capacities are increased in resistance training athletes, if the results would be different with a trained population.
06-05-2012, 09:51 AM
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