Grapefuit juice drug interactions Ketoconazole?

  1. Grapefuit juice drug interactions Ketoconazole?


    any info, not listed in PP list of interactions but the wiki page says some science stuff I don't understand about Ketoconazole and a interaction. Just want to make sure I'm not wasting my shampoo lol.


  2. Quote Originally Posted by tilldeath
    any info, not listed in PP list of interactions but the wiki page says some science stuff I don't understand about Ketoconazole and a interaction. Just want to make sure I'm not wasting my shampoo lol.
    I don't think it's a grapefruit drug. But I'm reading to avoid caffeine

  3. here's an excerpt form wiki

    Grapefruit juice has also been reported to increase both the bioavailability of some benzodiazepines, (such as diazepam) and greatly slow the rate of metabolisation.[12] An easy way to tell if a medication may be affected by grapefruit juice is by researching whether another known CYP3A4 inhibitor drug is already contraindicated with the active drug of the medication in question. Examples of such known CYP3A4 inhibitors include cisapride (Propulsid), erythromycin, itraconazole (Sporanox), ketoconazole (Nizoral), and mibefradil (Posicor)
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