As for EPA, the amount I posted was only my opinion. I can cite references for why I believe this but dont want to derail the thread too much. Overall nothing is really too conclusive but it is pretty clear there is a relationship between EPA/DHA supplementation and the HPA
As for
curcumin, admittedly the majority of studies are either in vitro or in rats with only a handful of human studies but in my opinion
curcumin still shows a great deal of potential. As far as its effects on cancer, yes that is one of the benefits but there is also evidence on its effects on numerous physiological systems with very little evidence pointing to side effects. Again I can cite references but dont wish to derail the thread, only expressing my opinion.
Now I do agree that curcumin's bioavailability is quite low, but large doses may circumvent any problems with absorption and yes piperine has been shown to also increase absorption. Lastly, it has also available encapsulated in lipid solvents (LEF) which would also possibly improve absorption.
Again, these are only my opinions and I only wanted to add to your thread, not challenge or debate you.