DAA-effects on the brain?

  1. sizematters10
    sizematters10's Avatar

    DAA-effects on the brain?


    wow my title is dumb, let me clarify. ive been away for about 6months from the forum and was just wondering if anybody or any general consensus on the effects of DAA and cognitive functioning/mood stabilization (understand probably two entirely different aspects) has been arrived upon. anyways anybody speeding me up on the debate would be awesome. From the recent posts I've checked out today seems like its not a bad idea to pair up with ERASE even though the possibility is small, and might work well with L-dopa 5on 2 off, something like that. in any case ive been itching to do DAA, and make it a staple. results seem kind of congruent with creatine, beta alanine, that solid so would love to hear what the communitys' position is...with some past recreational things ive taken i want to be very careful, thats in the past and im doing things with a purpose now and not wanting to diminish or inhibit my future potential. any new info would be cool!


  2. I was taking DAA with Endosurge and no Erase for my first Endo cycle in the fall and I liked part of it. I noticed an edge that I didn't have without it, and it was focused. It didn't consume me, but it was a controlled aggression. The only thing that I did notice was that I would get a slight headache about 30 min after taking it and I wasn't 100% comfortable with that. I read all about the effects on the brain and getting a headache didn't seem right, so I stopped taking it. The headaches never came back.

  3. it also gave me headaches at 3 grams but 1.5 grams did not.
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  4. I had headaches the first couple nights. NBD. Went away and felt like a shmillion bucks after!
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  5. sizematters10
    sizematters10's Avatar

    thanks for the feedback, anybody have links to the threads in which this is studied at length? mr. cooper any personal thoughts on this?
  6. sizematters10
    sizematters10's Avatar

    bumping only once...sorry if its annoying was just hoping to hear some feedback. if nobody replies i will let it die haha take it easy all of you AM'ers.

  7. DAA is a toxic aminoacid in high doses (+3 grs)

  8. I've heard that it can improve cognitive function and mood, and people have cited studies on it, although I'm not familiar with them. I noticed a slight difference in mood while I was running it, but can honestly say I've never had the headaches a few people here mentioned.
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  9. neurotransmitters toxicity

  10. Quote Originally Posted by DaveMcNaul
    DAA is a toxic aminoacid in high doses (+3 grs)
    Ooh? Would appreciate if you could present some evidence

  11. Quote Originally Posted by DaveMcNaul View Post
    DAA is a toxic aminoacid in high doses (+3 grs)
    so then test force-2 recommending 6g ed is a bad idea?

  12. Here are a couple that show NMDA(N-methyl-D-aspartatic acid) causing cell death and a search on Google will pull up several list that put it in excitotoxin category.
    Acute NMDA toxicity in cultured rat cerebellar gra... [BMC Neurosci. 2010] - PubMed result
    NMDA But Not Non-NMDA Excitotoxicity is Mediated by Poly(ADP-Ribose) Polymerase -- Mandir et al. 20 (21): 8005 -- Journal of Neuroscience
    What is NMDA?
    N-methyl-D-aspartic acid - Wikipedia, the free encyclopedia
    or just D aspartic acid
    Aspartic acid - Wikipedia, the free encyclopedia
    Muscle Warfare and several others are offering NMDA which is a more soluble form of D-aa.

  13. Quote Originally Posted by DaveMcNaul View Post
    Here are a couple that show NMDA(N-methyl-D-aspartatic acid) causing cell death and a search on Google will pull up several list that put it in excitotoxin category.
    Acute NMDA toxicity in cultured rat cerebellar gra... [BMC Neurosci. 2010] - PubMed result
    NMDA But Not Non-NMDA Excitotoxicity is Mediated by Poly(ADP-Ribose) Polymerase -- Mandir et al. 20 (21): 8005 -- Journal of Neuroscience
    What is NMDA?
    N-methyl-D-aspartic acid - Wikipedia, the free encyclopedia
    or just D aspartic acid
    Aspartic acid - Wikipedia, the free encyclopedia
    Muscle Warfare and several others are offering NMDA which is a more soluble form of D-aa.
    Those studies have limited value when trying to make human en vivo correlations.

  14. but ... studies in humans? how many time ?

  15. Also if the studies are the ones in thinking of that was n methyl daa injected straight into rats brain not takin orally

  16. We are freaking out a little too much about DAA in this thread.
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  17. ...goes and makes a DAA snowman and eats hime alive...muahuahuahuah!
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  18. NMDA only has a toxic effect if applied directly to brain tissue. Oral supplementation with NMDA or just regular DAA has never been shown to cause cell death, toxicity, etc.
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  19. sizematters10
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    Quote Originally Posted by allnatural923 View Post
    NMDA only has a toxic effect if applied directly to brain tissue. Oral supplementation with NMDA or just regular DAA has never been shown to cause cell death, toxicity, etc.

    thats very interesting...I wonder if its because of a lack of testing or because the difference in interaction between direct contact and ingesting truly is different.
  20. "The only good is knowledge and the only evil is ignorance." - Socrates
  21. sizematters10
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    Quote Originally Posted by JudoJosh View Post

    link is helpful, thanks!

  22. is very risky to say that it is not toxic
    in my personal experience, +3 grs, headache..

  23. Quote Originally Posted by DaveMcNaul View Post
    is very risky to say that it is not toxic
    in my personal experience, +3 grs, headache..
    Meh...

    I dont know how one would "feel" the toxicity but I was taking as high as 9g a day before and never "felt" any toxicity but again as I said I dont know how one would really "feel" neuro toxicity
    "The only good is knowledge and the only evil is ignorance." - Socrates
  

  
 

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