Coleus Forskholli in transdermal??

[dlucks]

Would it work better if I make the bulk powder into a transdermal?

 

[itzDodge]

The only advantage to making a transdermal for forskolin that I can think of is to avoid the runs at high doses(lower quality stuff as well), its generally just easier to take it orally and seeing as it works systemically making the delivery system and everything is just wasted effort. Also consider many things have poorer bio availability when absorbed through the skin.

I wouldn't, just dose it orally bro dawg

 

[mr.cooper69]

I wouldn't. Forskolin's effects are pretty systemic. A negative but irrelevant (due to dosage) effect is premature glycogen depletion, but it is nothing to worry about. On the flip side, testosterone is elevated by the increase in cAMP. IMO, the system benefits - costs outweigh the topical benefits - costs.

 

[criticalbench]

I would opt for it orally; some things are better transdermal, but forskholli is not one of them.

Mike

 

[cdiblasi]

The only advantage to making a transdermal for forskolin that I can think of is to avoid the runs at high doses(lower quality stuff as well), its generally just easier to take it orally and seeing as it works systemically making the delivery system and everything is just wasted effort. Also consider many things have poorer bio availability when absorbed through the skin.

I wouldn't, just dose it orally bro dawg

Say what? By that I'm hoping you mean that drugs are limited by their structure for transdermal administration (small and lipophilic will diffuse through the skin's membrane fairly easily). Being that it bypasses first-pass hepatic metabolism, drugs that fit the bill will have a higher availability than those drugs taken orally.

However, I do agree Forskolin should probably just be taken orally. I would never try to make my own transdermal patch and there's really not much of a reason to do so in the first place.

 

[dlucks]

Thanks for the info guys.

Ordered some c-bolic 95% forskolin. Ill post up a review after a month or so

 

[itzDodge]

Say what? By that I'm hoping you mean that drugs are limited by their structure for transdermal administration (small and lipophilic will diffuse through the skin's membrane fairly easily). Being that it bypasses first-pass hepatic metabolism, drugs that fit the bill will have a higher availability than those drugs taken orally.

However, I do agree Forskolin should probably just be taken orally. I would never try to make my own transdermal patch and there's really not much of a reason to do so in the first place.

Yah my point was based on the compound being able to permeate the skin, in the end its probably just easier to take Forskolin orally.

 

[oufinny]

Thanks for the info guys.

Ordered some c-bolic 95% forskolin. Ill post up a review after a month or so

I am planning on adding that to my PCT, curious what you think. Run an informal log man.

 

[itzDodge]

I am planning on adding that to my PCT, curious what you think. Run an informal log man.

Forskolin is something you could run solo on a recomp and see some results out of it, good stuff

 

[oufinny]

Forskolin is something you could run solo on a recomp and see some results out of it, good stuff

Yes that is why it is in BioForge, Drive, Recreate and many other products, it works as advertised. I like the test boosting aspect from a different MOA than what is in EndoSurge and of course a SERM.

 

[itzDodge]

Yes that is why it is in BioForge, Drive, Recreate and many other products, it works as advertised. I like the test boosting aspect from a different MOA than what is in EndoSurge and of course a SERM.

The test boosting effects are very minimal.