does erase effect cortisol

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  1. does erase effect cortisol


    A few days ago i read a thread where a few people claimed that studies show the compound in ERASE has no effect on cortisol. Then a PES rep came in and said they never claimed it to lower cortisol, only that it "may". This seems kinda odd to me because if you read any websites write up on ERASE almost the entire thing talks about how bad cortisol is and how erase lowers it. Just trying to figure out if I need to run something like Reduce XT along side it or if erase actually does lower cortisol. Thanks guys. . .


  2. There is some thought on this that Erase seems to have an effect on lowering cortisol. Is it's primary purpose to lower cortisol? No, but there does seem to be some residual effect.

    I personally always take a little extra vitamin C while taking erase, as that as well seems to have an anti-cortisol impact
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  3. lame... I just bought Erase, I was contemplating going to the Triazole/LeanXtreme. But I liked that Erase was an all in one and it's AI mechanism was suicide inhibitor so no chance of rebound like you would have with an normal AI or SERM

  4. Quote Originally Posted by Machmood View Post
    A few days ago i read a thread where a few people claimed that studies show the compound in ERASE has no effect on cortisol. Then a PES rep came in and said they never claimed it to lower cortisol, only that it "may". This seems kinda odd to me because if you read any websites write up on ERASE almost the entire thing talks about how bad cortisol is and how erase lowers it. Just trying to figure out if I need to run something like Reduce XT along side it or if erase actually does lower cortisol. Thanks guys. . .
    Here is the whole deal. OTC AI's are going to be a thing of the past here quite soon. Erase has enough anecdotal evidence and supporting information from chemists like RussianStar that it is our information on the write. If something is being marketed as an AI, you will see it leave the market that much quicker, regardless of the DSHEA, anything that lowers E is not considered to be a dietary supp in big brothers eyes. We stated it at the beginning that it was only theory, but that theory has held anecdotal true, and saliva test true from my own doing.

    As I said earlier, take it for what you will. The masses says cort control, and gun to my head I vouch for just that.
    The Historic PES Legend

  5. Quote Originally Posted by Machmood View Post
    A few days ago i read a thread where a few people claimed that studies show the compound in ERASE has no effect on cortisol. Then a PES rep came in and said they never claimed it to lower cortisol, only that it "may". This seems kinda odd to me because if you read any websites write up on ERASE almost the entire thing talks about how bad cortisol is and how erase lowers it. Just trying to figure out if I need to run something like Reduce XT along side it or if erase actually does lower cortisol. Thanks guys. . .
    There is no study showing that Erase has no effect on cortisol.

    Those who have used both AIs and cortisol reducers extensively, and used Erase, will be the first to tell you it hits both pathways

    The last thing you'd want to do is take an additional cort blocker along side it. You would find out extremely fast that it was not needed and regret purchasing 2 things.
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  6. Waiting for my Erase Alpha T2 to come in. I got it primarily for the AI and thought the added bonus of lowering cortisol. Thanks for the vitamin c tidbit- definitely helpful.
    By believing passionately in something that still does not exist, we create it. The nonexistent is whatever we have not sufficiently desired.
    Franz Kafka

  7. You'll love it!
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  8. Many (including myself) have been reporting leaning out quite a bit while on Erase. I don't think cortisol is going to be an issue.
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  9. it does not effect it at all...

    it may AFFECT it...
    Log of EPIC by FRL - http://anabolicminds.com/forum/supplement-reviews-logs/202576-should-epic-frl.html

  10. i have never tried it but from what I have read it does not effect it at all

  11. Quote Originally Posted by Machmood View Post
    A few days ago i read a thread where a few people claimed that studies show the compound in ERASE has no effect on cortisol. Then a PES rep came in and said they never claimed it to lower cortisol, only that it "may". This seems kinda odd to me because if you read any websites write up on ERASE almost the entire thing talks about how bad cortisol is and how erase lowers it. Just trying to figure out if I need to run something like Reduce XT along side it or if erase actually does lower cortisol. Thanks guys. . .
    Erase has cortisol control effects, yes. There is no need to run another cortisol control product alongside it, unless you low-dosed it.

    ~Rosie~
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  12. Quote Originally Posted by StangBanger View Post
    it does not effect it at all...

    it may AFFECT it...
    Damn the english language!
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  13. why not take a product thats proven to have an impact on cort?
    BPS Representative

  14. That makes too much sense. lol
    By believing passionately in something that still does not exist, we create it. The nonexistent is whatever we have not sufficiently desired.
    Franz Kafka

  15. Quote Originally Posted by R1balla View Post
    why not take a product thats proven to have an impact on cort?
    True.... You still could throw that in there if you wanted.

    SNS Reduce XT is a very solid and cost effective option.
    I'm Back...

  16. Quote Originally Posted by R1balla View Post
    why not take a product thats proven to have an impact on cort?
    Because if you add another one on top of erase and you down right crush it to nothing... bad news.

    Everyone thinks cort is so bad when in fact it is a necessary functional hormone.
    The Historic PES Legend

  17. Quote Originally Posted by R1balla View Post
    why not take a product thats proven to have an impact on cort?
    Because other cortisol control products dont lower estrogen as well
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  18. but free test Contains a natural suicide inhibitor will improve the Testosterone : Estrogen profile while also increasing testosterone levels

    free test contains about 110mg of 3,7 Keto which has demonstrated strong ability to lower estrogen

    so yes, Free Test does do all three. boost test, lower estro, cort control
    BPS Representative

  19. Quote Originally Posted by DAdams91982 View Post
    Because if you add another one on top of erase and you down right crush it to nothing... bad news.

    Everyone thinks cort is so bad when in fact it is a necessary functional hormone.
    i never said add another one on top of erase. i said take one that boosts test, controls estro and cort all in ONE product, not TWO
    BPS Representative

  20. Quote Originally Posted by R1balla View Post
    but free test Contains a natural suicide inhibitor will improve the Testosterone : Estrogen profile while also increasing testosterone levels

    free test contains about 110mg of 3,7 Keto which has demonstrated strong ability to lower estrogen

    so yes, Free Test does do all three. boost test, lower estro, cort control
    What in free test is proven to reduce cortisol?

  21. The theory of Erase lowering cortisol stems from the fact that 7-oxos conversion to metabolites hogs the 11-b hsd enzyme, similar to dheas conversion to testosterone using the 3b and 17b hsd enzymes. 11b hsd is responsible for converting inactive cortisone into the active form cortisol. Since 7 oxo is competively reducing the total amount of conversion taking place, you're left with less active cortisol.

    Erase is a metabolite of 7-oxo, so we hypothesized the possibility of it being a competitive inhibitor of this enzyme as well. It was pretty much confirmed after all the anecdotal reports we have received, as well as some people that have taken saliva adrenal stress index tests while on erase.
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  22. Interesting. Thanks for that.
    By believing passionately in something that still does not exist, we create it. The nonexistent is whatever we have not sufficiently desired.
    Franz Kafka

  23. Quote Originally Posted by OrganicShadow View Post
    Interesting. Thanks for that.
    No problem!
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  24. Quote Originally Posted by EasyEJL View Post
    What in free test is proven to reduce cortisol?
    3,7 Keto DHEA and 7-Keto DHEA derivatives in general tend to curb cortisol - there is a pretty good explanation in the tech write-up
    BPS Representative

  25. Quote Originally Posted by R1balla View Post
    3,7 Keto DHEA and 7-Keto DHEA derivatives in general tend to curb cortisol - there is a pretty good explanation in the tech write-up
    Explanation of theory isn't proof...... and you understand that's the same ingredient as in erase?

  26. but at a higher dose
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  27. Quote Originally Posted by R1balla View Post
    but at a higher dose
    It's in a proprietary blend.
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  28. Quote Originally Posted by R1balla View Post
    but at a higher dose
    If this is true (not doubting you) what is the dosage? As khy said, it is a proprietary blend, which will make many wonder

  29. yes it is in a prop blend, but there are about 110mg in 4 caps according to Dirk, which, if im not mistaken, is a higher dose than Erase which i believe is 75mg


    http://www.appliednutriceuticals.com...-free_test.php

    Regulating Estrogen and Increasing Testosterone via Suicide Aromatase Inhibition: The Role of 3, 7-Keto DHEA:

    * 3, 7-Keto DHEA is a naturally-occurring metabolite of dehydroepiandosterone (DHEA), and is a potent aromatase inhibitor with some very unique qualities. Aromatase is an enzyme that transforms testosterone into estrogen, and the more active aromatase is, the more estrogen will ultimately be present. Therefore, aromatase inhibitors significantly decrease the level of estrogen in the body. This is important as increased estrogen in men can signal the hypothalamic pituitary testicular axis (HPTA) to shut down the release of gonadotropin-releasing hormone (GnRH). GnRH signals the production of luteinizing hormone (LH), which signals the production of testosterone. Therefore, increased estrogen levels can lower endogenous testosterone production (21,29,31).

    * 3, 7-Keto DHEA has demonstrated strong ability to lower estrogen, thus mitigating this effect. It has a high binding affinity (Ki value = 0.22 mM) to the aromatase enzyme, and binds in an irreversible manner, making it a suicide inhibitor of aromatase. Ki Values measure how efficiently a compound binds to its associated receptor. The lower the Ki value; the higher the binding affinity. This inhibition allows for the production of less estradiol (E2) and estrone (E1) and allows the user of the compound to maintain a higher level of testosterone; hence improving the Testosterone: Estrogen (T:E) ratio. The mechanism through which aromatase inhibitors raise testosterone is fairly simple; the HPTA senses low levels of estrogen, and because the body seeks to maintain homeostasis (it likes to maintain at least some estrogen, even in men), there is a concurrent increase in the amount of testosterone that is being produced, as a way to compensate for the low estrogen levels. The increased testosterone levels normally will result in increased estrogen since there is no estrogen being produced. Essentially, the brain is tricked into trying to produce more estrogen, so it releases more luteinizing hormone releasing hormone (LHRH) and subsequently more LH, leading to even higher testosterone levels (20,21-23).

    * All aromatase inhibitors share this characteristic of positively altering the T:E ratio, and all will raise serum testosterone levels in men, which has been referenced in numerous studies. 3,7-Keto DHEA is comparable in potency to several other commonly available aromatase inhibitors. As explained above, a lower Ki value means higher potency, making it more potent than both Formestane and Exemestane, and very similar to androstentrione (ATD) (31,55).

    * 3,7-Keto DHEA is unique from other commonly used aromatase inhibitors in sports supplements in that it is a natural metabolite of 7-Keto DHEA and it cannot directly bind to the androgen receptor. 3,7-Keto DHEA (like 7-Keto DHEA) also cannot convert to testosterone, estrogen, or progesterone via any type of enzymatic reaction, so by strict definition it cannot in any way be considered a prohormone. This clearly differentiates it from other recently banned products that allow for the direct conversion to a controlled substance in the body (in either in trace amounts or full-scale conversion). This can not occur with 3,7-Keto DHEA, as it is formed naturally in humans from 7-Keto DHEA and can be readily found in humans in the amount of 5-7 ug/day (23-24).
    BPS Representative

  30. I love the uncertain qualifier 'about' that you have to throw in there. Regardless of what "Dirk" might say, until that labels changed it's still a hidden blend in my eyes. I'm not trying to hate on Free Test, its just the way it is.
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