possible role of NMDA receptors in muscle nerve transmission?
Muscle Nerve. 2011 Dec;44(6):987-9. doi: 10.1002/mus.22250.
NMDA receptors at the endplate of rat skeletal muscles: Precise postsynaptic localization.
Malomouzh AI, Nurullin LF, Arkhipova SS, Nikolsky EE.
Kazan Institute of Biochemistry and Biophysics, Russian Academy of Sciences, P.O. Box 30, Kazan 420111, Russia. firstname.lastname@example.org.
In this study we demonstrate expression of the N-methyl-D-aspartate receptor NR1 subunit in the rat neuromuscular junction of skeletal muscles of different functional types (extensor digitorum longus, soleus, and diaphragm muscles) using fluorescence immunocytochemistry. Electron microscopic immunocytochemistry has shown that the NR1 subunit is localized solely on the sarcolemma in the depths of the postsynaptic folds. These findings suggest participation of the glutamatergic signaling system in functioning of the adult mammalian neuromuscular junction.Muscle Nerve, 2011.
Copyright © 2011 Wiley Periodicals, Inc.
PMID: 22102472 [PubMed - in process]
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I tried taking DAA twice, both times I couldn't sleep a wink a couple of days after I started. Worst insomnia ever. Sucks because I bought 3 tubs, so had to give them away
This is all so very confusing and the consensus is, there is no consensus.What I've been able to gather so far regarding NMDA, is that it does more harm than good.
Any of the supposed "harm" that NMDA causes it when it's applied directly directly to brain matter. You plan on removing your skull and applying liberally? LOL nope
Everyone had concerns when DAA came out, and then everyone realized they were wayyyy overblown.
Same is here.
iForce's new INTIMIDATE is pure NMDA and is going to make quite a few people happy with some impressive results.
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the bad part is that despite the fact the stuff is gonna work, since we already know big brother will work just as good and probably better than little brother.....but again, no way we will know long term sides....and the short term sides will be similar to DAA of course. So I doubt we learn much new info other than I am certain the loggers results should be superior to DAA.