kill Fat Cells
- 12-20-2010, 10:45 AM
- 12-21-2010, 08:32 AM
A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
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- 12-22-2010, 12:28 PM
- 02-23-2011, 12:19 PM
- 02-23-2011, 02:03 PM
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- 02-23-2011, 02:17 PM
- 02-23-2011, 02:28 PM
i added yohimbine to the bottle of capsacian sold as arthritis relief. the 1st thing i noticed is the burn, then when i exercised i noticed increased sweat where i applied it. my abs are my weak spot so it took some time, but i definately could tell a difference. it is relatively cheap so i use it a couple of times a week. definately worth a shot.
btw-the capsacian works considerably better than the absorbine jr that i had added yohimbine to previously.ICONIC FORMULATIONS REPRESENTATIVE
use code THEBIGT for 25% off - 02-23-2011, 02:34 PM
5 caps of Free Test contains an effective dose of all three compounds- by effective dose- we tend to use the doses used in scientific literature, where applicable....
Quercetin is a great compound, but a huge pain in the ass to work with- that's why you don't see it in more products. It has a waxy texture that tends to jam automatic capsule machines, plus it is a strong die that tends to coat and stain just about everything (even the FRP inside our clean room, LOL). The only thing that removes it is Krud Kutter- alcohol and bleach are no match for it- it will stain SS
Tell you a funny story- we have a pneumatic ejection pin system on our automatic capsule machine, and the the system ejects capsules out into an enclosed bin. The bin has a special suction that clears associated dust that goes along with each ejection- unfortunately, it quit working one day when we were making Free Test- so basically the dust from an entire 300K capsule run got deposited all over the encapsulation area. Problem is, you don't really see it until it starts to accumulate- I have never seen a mess like that in my entire life- took us 2 days to clean up after that run.....
Can you re-send the PMDirk Tanis, BA, MSci
Chief Operating Officer, Applied Nutriceuticals - 02-23-2011, 02:47 PM
- 02-23-2011, 02:52 PM
LOL- it looked liked someone dropped a pollen bomb in there- went right through everyones' lab coats...
Dirk Tanis, BA, MSci
Chief Operating Officer, Applied Nutriceuticals - 02-23-2011, 11:52 PMGain Strength. Add Lean Mass. Recover Faster. : ERGONINE
- 02-24-2011, 12:31 AM
I've looked into that as well pgcl in a transdermal form. Never decided to do it though. Its easy to get and very cheap but I have also been debating between small very shallow frequent injections of lipodissolve.
I have now decided though, I am just getting ab/torso lipo when I get my gyno surgery in less than a year hopefully.Hi-Tech Pharmaceuticals Representative - 02-24-2011, 12:50 AM
I use Quercetin to rid my gout and it works just as well as the meds im perscribed. I started to use NAC regularly last year and found out its best to add extremely high doses of Vit. C, other wise NAC will interfere with insulin sensitivity or something like that. As for Resveratrol I wish I could take Sustain Alpha year round...Perhaps Primordial Performance will release a Liquavade Trans-Resvertrol solo.
Primordial Performance
( at heart ) - 02-24-2011, 06:19 AM
- 02-25-2011, 10:24 AM
It's important to note though that as these theoretical (or real) products would be killing fat cells, not just decreasing their volume, they should still be targetted for morbidly obese folks. It takes a lot to actually cause adipose hyperplasia, and a long time to develop it, too, so even if you were still say at 25% bf and looking to drop, if you have only had that for a few years I would be very wary of using such products since you don't have a lot of adipose cells (just really inflated ones).
- 02-25-2011, 10:47 AM
- 02-25-2011, 12:05 PM
- 02-25-2011, 03:39 PM
Cissus will get rid of gout as well
As far as NAC- the effects seem to be negligible on insulin sensitivity:
J Physiol. 2010 May 1;588(Pt 9):1623-34. Epub 2010 Mar 22.
N-Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans.
Merry TL, Wadley GD, Stathis CG, Garnham AP, Rattigan S, Hargreaves M, McConell GK.
Department of Physiology, The University of Melbourne, Parkville, Victoria, 3010, Australia. [email protected]
Abstract
There is evidence that reactive oxygen species (ROS) signalling is required for normal increases in glucose uptake during contraction of isolated mouse skeletal muscle, and that AMP-activated protein kinase (AMPK) is involved. The aim of this study was to determine whether ROS signalling is involved in the regulation of glucose disposal and AMPK activation during moderate-intensity exercise in humans. Nine healthy males completed 80 min of cycle ergometry at 62 +/- 1% of peak oxygen consumption ( V(O(2)peak).A 6,6-(2)H-glucose tracer was infused at rest and during exercise, and in a double-blind randomised cross-over design, N-acetylcysteine (NAC) or saline (CON) was co-infused. NAC was infused at 125 mg kg(1) h(1) for 15 min and then at 25 mg kg(1) h(1) for 20 min before and throughout exercise. NAC infusion elevated plasma NAC and cysteine, and muscle NAC and cysteine concentrations during exercise. Although neither NAC infusion nor exercise significantly affected muscle reduced or oxidised glutathione (GSH or GSSG) concentration (P > 0.05), S-glutathionylation (an indicator of oxidative stress) of a protein band of approximately 270 kDa was increased approximately 3-fold with contraction and this increase was prevented by NAC infusion. Despite this, exercised-induced increases in tracer determined glucose disposal, plasma lactate, plasma non-esterified fatty acids (NEFAs), and decreases in plasma insulin were not affected by NAC infusion. In addition, skeletal muscle AMPKalpha and acetyl-CoA carboxylase-beta (ACCbeta) phosphorylation increased during exercise by approximately 3- and approximately 6-fold (P < 0.05), respectively, and this was not affected by NAC infusion. Unlike findings in mouse muscle ex vivo, NAC does not attenuate skeletal muscle glucose disposal or AMPK activation during moderate-intensity exercise in humans.
J Endocrinol Invest. 2009 Apr;32(4):352-6.
N-acetylcysteine is able to reduce the oxidation status and the endothelial activation after a high-glucose content meal in patients with Type 2 diabetes mellitus.
Masha A, Brocato L, Dinatale S, Mascia C, Biasi F, Martina V.
Department of Internal Medicine, Division of Endocrinology, University of Turin, Corso A.M. Dogliotti 14, 10126 Turin, Italy.
Abstract
Post-prandial hyperglycemia seems to play a pivotal role in the pathogenesis of the cardiovascular complications of diabetes mellitus, as it leads to an oxidative stress which in turn causes a reduced NO bioavailability. These conditions produce an endothelial activation.
AIM OF THE STUDY: The aim of this study was to assure that the administration of N-acetylcysteine (NAC), thiolic antioxidant, is able to decrease the oxidation status and endothelial activation after a high-glucose content meal.
SUBJECTS AND METHODS: Ten patients with Type 2 diabetes mellitus (DMT2) (Group 1) and 10 normal subjects (Group 2) were studied. They assumed a high-glucose content meal without (phase A) or after (phase B) the administration of NAC. Glycemia, insulinemia, intercellular adhesion molecule 1, vascular adhesion molecule 1 (VCAM-1), E-selectin, malonaldehyde (MDA), and 4-hydroxynonenal (HNE) were assessed at -30, 0, +30, +60, +90, +120, and +180 min with respect to the meal consumption.
RESULTS: During the phase A in Group 1, only HNE and MDA levels increased after the meal assumption; all parameters remained unchanged in Group 2. During the phase B, in Group 1, HNE, MDA, VCAM-1, and E-selectin levels after the meal were lower than those in phase A, while no change for all variables were observed in Group 2.
CONCLUSIONS: A high-glucose meal produces an increase in oxidation parameters in patients with DMT2. The administration of NAC reduces the oxidative stress and, by doing so, reduces the endothelial activation. In conclusion, NAC could be efficacious in the slackening of the progression of vascular damage in DMT2.Dirk Tanis, BA, MSci
Chief Operating Officer, Applied Nutriceuticals - 02-27-2011, 03:21 AM
- 02-27-2011, 04:41 PM
- 02-27-2011, 10:02 PM
Yeah I can vouch for that, we never monitor blood glucose during APAP overdoses when giving mucomyst (NAC) and believe me some amazingly high doses are given.
Gain Strength. Add Lean Mass. Recover Faster. : ERGONINE - 02-27-2011, 10:19 PM
"PPAR-gamma" and CLA?
isnt the PPAR-gamma involved or influenced by TTA too?The difference between who you are and who you want to be is what you do.
- 02-28-2011, 07:46 AM
- 02-28-2011, 09:49 AM
- 02-28-2011, 09:57 AM
I know it's not a supplement but it does kill fat cells...
http://abcnews.go.com/Health/freezin...ry?****11641994
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