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Oral steroids can cause liver damage; Liver Juice can support the liver

  1.  02-23-2010  08:53 PM
    Primordial Performance Rep Jimbo15's Avatar
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    Oral steroids can cause liver damage; Liver Juice can support the liver




    Dear AM,

    Liver Juice is now available.

    New research suggests that supplementing with Liver Juice before and during your cycle, can greatly reduce the liver toxic effect from 17aa methylated steroids. Its works by increasing bile production in the liver and reducing the chance of developing reversible cholestasis. (the primary condition developed from use of 17aa oral steroids)(1-18)

    Because Liver Juice delivers milk thistle so efficiently with the Liqua-Vade delivery system, it is one of the most cost effective milk thistle supplements on the market.

    Liver Juice -

    • Natural liver protector, rejuvenator and cleanser
    • Absorbs 8x better than other milk thistle extracts
    • Increases production of healthy bile salts
    • Natural milk thistle extract has zero side-effects
    • Protective against oral steroid induced toxicity


    Unmatched Delivery System

    To show the exceptional solubility accomplished with the milk thistle in our Liver Juice, we went ahead and took a 5mL dose (500mg) of Liver Juice and mixed it into a glass of water. We then took 500mg of the exact same milk thistle extract used in our Liver Juice, and vigorously shook it into a glass of water. Then they sat for 12 hours.


    As you can see, the milk thistle in Liver Juice remained completely stable and molecularly dispersed in the liquid. The milk thistle powder alone simply crashed to the bottom of glass. (“crash” means to crystallize, separate or no longer be in solution -- aka, not be absorbed into the body)







    Jim Benvie,
    Primordial Performance Marketing


    Questions?


    Phone – 1-800-568-2924
    Email - info@primordialperformance.com
    Visit - Primordial Performance



    References
    1. Silymarin: a review of its clincal properties in the managment of hepatic disorders
    Keri et al.
    Adis Drug Evaluation, Biodrugs 2001: 15 (7): 465-489

    2. Use of herbal supplements for chronic liver disease.
    Cynthia Levy et al.
    Clin. Gast. And Hepat. 2004;2:947-956

    3. Updated medicines and the liver.
    Fogden E et al.
    Liver International 2003, 23, 213-220

    4. An updated systemic review of the pharmacology of silymarin
    Reinhard Saller et al.
    Forsch Komplementarmed 2007;14:70-80

    5. Anabolic steroids and cholestasis
    Nusinovici V.
    Med Chir Dig. 1974;3(3):167-71.

    6. Cholestasis due to anabolic steroids
    Horký J, et al.
    Cesk Gastroenterol Vyz. 1973 Dec;27(8):548-50.

    7. Drug-induced cholestasis.
    Velayudham LS, et al.
    Expert Opin Drug Saf. 2003 May;2(3):287-304.

    8. Beneficial drugs for liver diseases.
    Muriel P, et al.
    J Appl Toxicol. 2008 Mar;28(2):93-103. Review.

    9. Silymarin as a new hepatoprotective agent in experimental cholestasis: new possibilities for an ancient medication.
    Crocenzi FA, Roma MG.
    Curr Med Chem. 2006;13(9):1055-74. Review.

    10. Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: possible involvement of cAMP.
    Crocenzi FA, et al.
    Biochem Pharmacol. 2005 Apr 1;69(7):1113-20.

    11. Beneficial effects of silymarin on estrogen-induced cholestasis in the rat: a study in vivo and in isolated hepatocyte couplets.
    Crocenzi FA, et al.
    Hepatology. 2001 Aug;34(2):329-39.

    12. Tauro alpha-muricholate is as effective as tauro beta-muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat.
    Kitani K, et al.
    Hepatology. 1994 Apr;19(4):1007-12.

    13. Tauro beta-muricholate is as effective as tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat.
    Kanai S, et al.
    Life Sci. 1990;47(26):2421-8.

    14. Cholestatic Jaundice and IgA Nephropathy Induced by OTC Muscle Building Agent Superdrol.
    Beata Jasiurkowski MD, et al.
    The American Journal of Gastroenterology (2006) 101, 2659-2662;

    15. Severe Cholestasis and Renal Failure Associated with the Use of the Designer Steroid Superdrol (Methasteron): A Case Report and Literature Review
    John Nasr and Jawad Ahmad
    Digestive Diseases and Sciences

    16. Improvement of estradiol-17b-d-glucoronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats.
    Kinbara S et al.
    Pharm. Research Laboratory, 1997, 947-952

    17. Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: Role in prevention of estrogen-induced cholestasis.
    Enrique J et al.
    The Journal of Pharmacology and experimental therapeutics, 2003 Vol. 306, No. 1 279-286

    18. Milk thistle (silybum marianum) for the therapy of liver disease
    Kenneth Flora et al.
    The American Journal of Gastroenterology. Vol. 93, No. 2, 1998



  2.  02-23-2010  08:56 PM
    Primordial Performance Rep Jimbo15's Avatar
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    •   


        
       

  3.  02-23-2010  10:08 PM
    Sponsor R1balla's Avatar
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    this company has the best products out IMO. how can i become a rep lol
    BioCor Nutrition - Please check out our line by clicking on the product below.
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  4.  02-23-2010  10:33 PM
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    Originally Posted by R1balla View Post
    this company has the best products out IMO. how can i become a rep lol
    You have to fly out to Portland OR and beat me in an arm wrestling competition. Then we talk.

    -Eric
    www.primordialperformance.com
    Please no PM's. I don't check them often. If you want a fast response please email me, or get in touch with one of the PP reps. I don't get on the forums often, so if I don't respond to your post, please don't be offended. -eric

  5.  02-24-2010  02:40 AM
    UKStrength
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    Originally Posted by Primordial Perf View Post
    You have to fly out to Portland OR and beat me in an arm wrestling competition. Then we talk.

    -Eric
    I gave Eric a slave to be a rep, it was the only way...the arm wrestling was too tough!

  6.  02-24-2010  09:51 AM
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    im on my way!
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  7.  02-24-2010  10:32 AM
    Registered User kingdong's Avatar
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    With regular Milk Thistle, I noticed my skin clear up for two weeks, and then I had a bad breakout at the end of those two weeks. Any chance of that on this product?

  8.  02-24-2010  06:29 PM
    Registered User JN230's Avatar
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    nice to see PP put out another quality Liqua vade product ill def have to grab some of this for my net methyl run.... im thinking maybe turinabol LV or something softer like that

  9.  02-24-2010  06:46 PM
    Primordial Performance Rep Jimbo15's Avatar
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    Originally Posted by UKStrength View Post
    I gave Eric a slave to be a rep, it was the only way...the arm wrestling was too tough!
    Thanks bro, she's a big help around the house

  10.  02-24-2010  06:50 PM
    Registered User Mase64's Avatar
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    Deff buying someeeeee!

  11.  02-24-2010  08:18 PM
    Registered User kingdong's Avatar
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    I thought liqua vade was supposed to get stuff PAST your liver. Isn't that how it works in Sustain Alpha?

  12.  02-25-2010  09:09 AM
    Registered User trojanman1016's Avatar
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    Originally Posted by UKStrength View Post
    I gave Eric a slave to be a rep, it was the only way...the arm wrestling was too tough!
    Hahaha, but i have to agree that PP makes the best products hands down, which makes it the best company. You guys are great keep it up. Oh and yea liver juice is the best milk thstle supplement and it has become a staple supplement for me!!!!!

  13.  02-25-2010  01:51 PM
    Board Sponsor Primordial Perf's Avatar
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    Originally Posted by kingdong View Post
    I thought liqua vade was supposed to get stuff PAST your liver. Isn't that how it works in Sustain Alpha?
    LV gets compounds past the intestinal walls. What happens from their is upto the compound.

    (although if you swoosh LV around in the mouth some of the active compounds will absorb directly into the blood and avoid the fist liver pass)

    -Eric
    www.primordialperformance.com
    Please no PM's. I don't check them often. If you want a fast response please email me, or get in touch with one of the PP reps. I don't get on the forums often, so if I don't respond to your post, please don't be offended. -eric

  14.  03-11-2010  03:38 PM
    Primordial Performance Rep Jimbo15's Avatar
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    anyone start a cycle with this yet?

  15.  04-28-2010  01:56 PM
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    Originally Posted by trojanman1016 View Post
    Hahaha, but i have to agree that PP makes the best products hands down, which makes it the best company. You guys are great keep it up. Oh and yea liver juice is the best milk thstle supplement and it has become a staple supplement for me!!!!!
    Glad to know.

    Ive got some interesting research here about milk thistle lowering cholesterol, presumably by increasing bile acid formation from cholesterol in the liver...

    I was going to make a write up soon.

    Silymarin as a potential hypocholesterolaemic drug.
    N. Scottova et al.
    Physiol. Res. 47; 1-7, 1998


    -Eric
    www.primordialperformance.com
    Please no PM's. I don't check them often. If you want a fast response please email me, or get in touch with one of the PP reps. I don't get on the forums often, so if I don't respond to your post, please don't be offended. -eric

  16.  04-28-2010  01:58 PM
    Registered User Heracles25's Avatar
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    How does this product compare to NAC or SAMe? From everything that I have read NAC or SAMe owns milk thistle on many levels. Not just as a liver protectant.

  17.  04-28-2010  06:14 PM
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    Originally Posted by Heracles25 View Post
    How does this product compare to NAC or SAMe? From everything that I have read NAC or SAMe owns milk thistle on many levels. Not just as a liver protectant.
    Their different products with different actions.

    Milk Thistle (and UDCA type bile acids) are the only compounds Im aware of that will really help prevent steroid induced choestasis, which is really want you want. SAMe can help with increase the sulfation pathway which can possibly protect against cholestasis but I wouldn't say its better than milk thistle -- it could be stacked though.

    -Eric
    www.primordialperformance.com
    Please no PM's. I don't check them often. If you want a fast response please email me, or get in touch with one of the PP reps. I don't get on the forums often, so if I don't respond to your post, please don't be offended. -eric

  18.  04-29-2010  10:07 AM
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    Originally Posted by Primordial Perf View Post
    Glad to know.

    Ive got some interesting research here about milk thistle lowering cholesterol, presumably by increasing bile acid formation from cholesterol in the liver...

    I was going to make a write up soon.

    Silymarin as a potential hypocholesterolaemic drug.
    N. Scottova et al.
    Physiol. Res. 47; 1-7, 1998


    -Eric
    That got my attention! Definatly looking forward to reading that.

  19.  06-18-2010  05:18 PM
    Primordial Performance Rep Jimbo15's Avatar
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  20.  06-18-2010  05:24 PM
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    might get some of that for my hdrol 6 week cycle
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