HarryManback
Member
- Awards
- 0
Got this in my email today from the FRS people. Could be old but figured I would post it:
J. Mark Davis, Catherine J. Carlstedt, Stephen Chen, Martin D. Carmichael, and E.
Angela Murphy1
Quercetin, a natural polyphenolic flavonoid substance present in a variety of food
plants, has been shown in vitro and in animal studies to have widespread health and
performance benefits resulting from a combination of biological properties, including
antioxidant and anti-inflammatory activity, as well as the ability to increase
mitochondrial biogenesis. Little is known about these effects in humans, however,
especially with respect to exercise performance. The authors determined whether
quercetin ingestion would enhance maximal aerobic capacity and delay fatigue during
prolonged exercise in healthy but untrained participants. Twelve volunteers were
randomly assigned to 1 of 2 treatments: (a) 500 mg of quercetin twice daily dissolved in
vitamin-enriched Tang or (b) a nondistinguishable placebo (Tang). Baseline VO2max and
bike-ride times to fatigue were established. Treatments were administered for a period
of 7 days using a randomized, double-blind, placebo-controlled, crossover study
design. After treatment both VO2max and ride time to fatigue were determined. Seven
days of quercetin feedings were associated with a modest increase in VO2max (3.9% vs.
placebo; p < .05) along with a substantial (13.2%) increase in ride time to fatigue (p <
.05). These data suggest that as little as 7 days of quercetin supplementation can
increase endurance without exercise training in untrained participants. These benefits
of quercetin may have important implications for enhancement of athletic and military
performance. This apparent increase in fitness without exercise training may have
implications beyond that of performance enhancement to health promotion and
disease prevention.
1The authors
J. Mark Davis, Catherine J. Carlstedt, Stephen Chen, Martin D. Carmichael, and E.
Angela Murphy1
Quercetin, a natural polyphenolic flavonoid substance present in a variety of food
plants, has been shown in vitro and in animal studies to have widespread health and
performance benefits resulting from a combination of biological properties, including
antioxidant and anti-inflammatory activity, as well as the ability to increase
mitochondrial biogenesis. Little is known about these effects in humans, however,
especially with respect to exercise performance. The authors determined whether
quercetin ingestion would enhance maximal aerobic capacity and delay fatigue during
prolonged exercise in healthy but untrained participants. Twelve volunteers were
randomly assigned to 1 of 2 treatments: (a) 500 mg of quercetin twice daily dissolved in
vitamin-enriched Tang or (b) a nondistinguishable placebo (Tang). Baseline VO2max and
bike-ride times to fatigue were established. Treatments were administered for a period
of 7 days using a randomized, double-blind, placebo-controlled, crossover study
design. After treatment both VO2max and ride time to fatigue were determined. Seven
days of quercetin feedings were associated with a modest increase in VO2max (3.9% vs.
placebo; p < .05) along with a substantial (13.2%) increase in ride time to fatigue (p <
.05). These data suggest that as little as 7 days of quercetin supplementation can
increase endurance without exercise training in untrained participants. These benefits
of quercetin may have important implications for enhancement of athletic and military
performance. This apparent increase in fitness without exercise training may have
implications beyond that of performance enhancement to health promotion and
disease prevention.
1The authors
